STRATIFYING THE RISK OF ADVERSE CARDIOVASCULAR EVENTS IN ACUTE MYOCARDIAL INFARCTION WITH ST-SEGMENT ELEVATION
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Objective: The aim of our study was to evaluate the prognostic role of β-APM in patients for myocardial infarction with segment elevation ST (STEMI). Materials and Methods: In the present research, carried out the study of β-adrenoreception erythrocyte membranes (β-APM) in 81 patients with myocardial infarction with ST-segment elevation with a different course of the disease. β-adrenoreactivity of organism was determined by the value of β-APM using the diagnostic reagent kit "ARM-agate" (LLC "Agat-Med", Moscow). All patients were divided into 2 groups. 1st group consisted of 49 patients who did not have complications, both in hospital period and post it. In the 2nd group consisted of the 32 patients with different complications of the cardiovascular system. Results: In patients with STEMI average value of β-APM in the 2 groups was 29,9 ±1,24 The average value of β-APM in the first group was significantly 34,07 ±1,6 (p<0.05). In the 2 nd group, the mean value of β-APM was 23,5 ±1,31 (p<0.05), against 19,2 ±2,3 (p<0.05) in the control group, respectively. The findings led to the conclusion that the initial value of β-APM with STEMI may have prognostic value, within a year of onset. In patients with STEMI at a low β-APM were highly probability to develop complications. With high rates of β-APM in contrast, it is a favorable prognostic sign. Conclusions: Thus, we suggest that in patients of myocardial infarction with ST-segment elevation at the β-APM is less than 20 is a poor prognostic indicator in the development of cardiovascular complications.
Alfiya О. Aimagambetova 1*, http://orcid.org/0000-0003-1496-3281 Lyudmila K.Karazhanova 1, http://orcid.org/0000-0002-4719-6034 Arkady-Avi Kotlyar 2-3, http://orcid.org/0000-0002-5070-0000 Meiramgul O. Tokbulatova 1, http://orcid.org/0000-0003-3859-4812 1 Semey State Medical University, Department of therapy internship, Semey, Kazakhstan; 2 Hospital «Kaplan», Rehovot, Israel; 3 Hospital «Integrative medicine», Rishon Le Zion, Israel
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