COMPREHENSIVE CHROMOSOMAL ABERRATION TEST IN THE POPULATION OF SEMEY REGION OF KAZAKHSTAN

The objects of the study was a population of Abay and Beskaragai regions of the East Kazakhstan region, living in the area covered by the former Semipalatinsk nuclear test site.

Purpose - a comprehensive cytogenetic analysis of the population living in radiation-contaminated areas.

In the process, were selected group of persons who are descendants (second, third generation) of the population living in the period of atmospheric, surface and underground explosions at designated areas. They held the fence biological material (peripheral blood) and cytogenetic studies performed to identify chromosomal aberrations routine and FISH (in situ hybridization) methods.

As a result of our work, we defined and studied the frequency and types of chromosomal aberrations in generations of descendants of persons living in radiation-contaminated areas. A comprehensive analysis and the evaluation of the identified chromosomal abnormalities in peripheral blood lymphocytes and calculated dose irradiation incorporated in the descendants living in the study area.

M. R. Madiyeva, N. Zh. Chaizhunussova,

A. Zh. Saimova, A. Zh. Abylgazinova

Semey State Medical University, Kazakhstan

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Bibliography link

Madiyeva M. R., Chaizhunussova N. ZH., Saimova A. ZH., Abylgazinova A. ZH. Comprehensive chromosomal aberration test in the population of Semey region of Kazakhstan Nauka i Zdravoohranenie [Science & Healthcare]. 2015, 3, pp. 57-63.


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