RESTRUCTURING REGULARITIES OF AXILLARY AREA LIMPHATIC VESSELS IN BREAST CANCER
The aim is identify patterns of macroscopic changes in the structure of the axillary lymphatic system in breast cancer.
Material and methods. The objects of this study were the complex tissue taken from 100 females, during surgery for breast cancer and treated by sonolipodestruction.
Results. Analysis of lymph maps allowed to develop a combined functional state graduation scheme of the lymph nodes and highlight the types of axillary lymph collector restructured “Successive”, “Magistral”, “Uniform”, “Radial”, “Reticulated”. It was calculated incidence of a particular type of axillary lymphatic system.
Conclusion. The proposed classification is conditional, not be excluded that the transition of one type of axillary lymph collector to another, that is, maybe it's the same process steps in various fixed points in time.
Sh. Kh. Gantsev, Sh. R. Kzyrgalin, A. N. Kayumova
Scientific Research Institute of Oncology at Bashkortostan State Medical University, Ufa, Russian Federation
1. Бородин Ю. И., Сапин М. Р., Этинген Л. Е., Григорьев В. Н. Общая анатомия лимфатической системы. Новосибирск: Наука СО, 1990. 243 с.
2. Ганцев Ш. Х., Галеев М. Г., Ишмуратова Р. Ш., Хуснутдинов Ш. М., Ганцев К. Ш., Султанбаев А. В. и др. Аксилярный лимфатический аппарат при раке молочной железы. М.: МИА, 2011. 194 с.
3. Дычарский Л. Ю. Проблемы профилактики и лечения рака молочной железы. Организация противораковой борьбы, профилактика злокачественных опухолей: сб. науч. Трудов. Л.: Медицина, 1976. C. 90-100.
4. Есенкулов А. Е., Молдахметов С. К. Патологический подход к выявлению ранних стадий рака молочной железы // Актуальные проблемы профилактики и лечения рака молочной железы: матариалы науч.-прак. конф. СПб., 1993. С. 39–40.
5. Заридзе Д. Г. Эпидемиология и профилактика рака // Вестник РАМН, 2001. №9. С. 6–14.
6. Каприн А. Д., Старинский В. В., Петрова Г. В. Злокачественные новообразо-вания в России в 2013 году (заболеваемость и смертность). М.: МНИОИ им. П.А. Герцена филиал ФГБУ «НМИРЦ» Минздрава России, 2015. 250 с.
7. Каприн А. Д., Старинский В. В., Петрова Г. В. Злокачественные новообразо-вания в России в 2014 году (заболеваемость и смертность). М.: МНИОИ им. П.А. Герцена - филиал ФГБУ «НМИРЦ» Минздрава России, 2016. 250 с.
8. Напалков Н. П., Мерабишвили В. М., Церковный Г. Ф. Заболеваемость населения СССР злокачественными новообразованиями // Злокачественные новообразования в СССР: сб. науч. трудов. Л., 1980. C. 22-103.
9. Семиглазов В. Ф. Нургазиев К. Ш., Арзуманов A. C. Опухоли молочной железы: лечение и профилактика. Алма-Ата, 2001. 344 с.
10. Семиглазов В. Ф. Проблема рака молочной железы на пороге XXI века. СПб., 1997. 117 с.
11. Семиглазов В. Ф. Пути повышения эффективности лечения рака молочной железы // Вопросы онкологии. 2003. Т. 49. № 7. С.467–469.
12. Старинский В. В., Петрова Г. В., Чиссов В. И. и др. Заболеваемость населения России злокачественными заболеваниями в 2000 г. // Российский онкологический журнал. 2002. № 3. С. 39–44.
13. Dvorak H. F. Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumour angiogenesis and a potential target for diagnosis and therapy // J. Clin. Oncol. 2002. 20. P. 4368 – 4380.
14. Fidler I. J., Balch C. M. The biology of cancer metastasis and implications for therapy // Curr Probl Surg. 1987. № 24. P. 129-209.
15. Gomes F. G., Nedel F., Alves A. M., Nor J. E., Tarquinio S. B. Tumor angiogenesis and lymphangiogenesis: tumor endothelial crosstalk and cellular microenvironmental signaling mechanisms // Life Sci. 2013. №2. P. 101 – 107.
16. Lauria R., Perrone F., Carlomagno C., De Laurentiis M. et al. The prognostic value of lymphatic and blood vessel invasion in operable breast cancer // Cancer. 1995. № 76. P. 1772-1778.
17. Schoppmann S. F., Horvat R., Birner P. Lymphatic vessels and lymphangiogenesis in female cancer: mechanisms, clinical impact and possible implications for anti-lymphangiogenic therapies (Review) // Oncol.Rep. 2002. № 9. P.455–460.
18. Sporn M. B. The war on cancer // Lancet. 1996. № 347. P.1377-1381.
19. Swartz M., Lund A. Lymphatic and interstitial flow in the tumour microenvironment: linking mechanobiology with immunity // Nature. 2012. №12. Р. 210 – 219.
20. Weitman E., Cuzzone D., Mehrara B. J. Tissue engineering and regeneration of lymphatic structures // Future Oncol. 2013. №9: Р.1365–1374.
References:
1. Borodin J. I., Sapin M. R., Etingen L. E. i dr. Obshchaya anatomiya limfaticheskoi sistemy [General anatomy of the lymphatic system]. Novosibirsk: Nauka SO, 1990, 243 p.
2. Gantsev Sh. H., Galeev M. G., Ishmuratova R. Sh. i dr. Aksilyarnyi limfaticheskii apparat pri rake molochnoi zhelezy [Axillary lymphatic apparatus in breast cancer]. M.: MIA; 2011, 194 p.
3. Dycharskii L. Y. Problemy profilaktiki i lecheniya raka molochnoi zhelezy. Organizatsiya protivorakovoi bor'by, profilaktika zlokachestvennykh opukholei: sb. nauch. trudov. [Problems prevention and treatment of breast cancer. The organization of cancer control, prevention of malignant tumors: a collection of scientific papers. L.: Meditsina, 1976, pp 90-100.
4. Esenkulov А. E., Moldakhmetov S. K. Patologicheskii podkhod k vyyavleniyu rannikh stadii raka molochnoi zhelezy [The pathological approach to the identification of the early stages of breast cancer]. Аktual'nye problemy profilaktiki i lecheniya raka molochnoi zhelezy: matarialy nauch. prak. konf. [Actual problems of prevention and treatment of breast cancer: materials of scient. pract. conf.]. SPb., 1993, pp. 39–40.
5. Zaridze D. G. Epidemiologiya i profilaktika raka [Epidemiology and prevention of cancer]. Vestnik RАMN [Herald RAMS]. 2001. 9. pp. 6–14.
6. Kaprin А. D. Zlokachestvennye novoobrazovaniya v Rossii v 2013 godu (zabolevaemost' i smertnost') [Malignancies in Russia in 2013 (morbidity and mortality)]. M.: MNIOI im. P.А. Gertsena filial FGBU «NMIRTS» Minzdrava Rossii. 2015. 250 p.
7. Kaprin А. D. Zlokachestvennye novoobrazovaniya v Rossii v 2014 godu (zabolevaemost' i smertnost') [Malignancies in Russia in 2013 (morbidity and mortality)]. M.: MNIOI im. P.А. Gertsena filial FGBU «NMIRTS» Minzdrava Rossii. 2015. 250 p.
8. Napalkov N. P., Merabishvili V. M., Tserkovnyi G. F. Zabolevaemost' naseleniya SSSR zlokachestvennymi novoobrazovaniyami [Incidence of malignant neoplasms in the USSR]. Zlokachestvennye novoobrazovaniya v SSSR: sb. nauch. trudov [Malignancies in the Soviet Union: collection of scientific papers]. L., 1980. pp. 22–103.
9. Semiglazov V. F., Nurgaziev K. SH., Аrzumanov A. C. Opukholi molochnoi zhelezy: lechenie i profilaktika [Breast tumors: treatment and prevention]. Аlma-Аta, 2001, 344 p.
10. Semiglazov V. F. Problema raka molochnoi zhelezy na poroge XXI veka [The problem of breast cancer at the XXI century]. SPb., 1997, 117 p.
11. Semiglazov V. F. Puti povysheniya effektivnosti lecheniya raka molochnoi zhelezy [Ways to improve the effectiveness of breast cancer treatment] Voprosy onkologii [Issues of Oncology]. 2003, T. 49, 7. pp. 467–469.
12. Starinskii V. V., Petrova G. V., Chissov V. I. et al. Zabolevaemost' naseleniya Rossii zlokachestvennymi zabolevaniyami v 2000 g. [The incidence of malignant diseases of the Russian population in 2000]. Rossiiskii onkologicheskii zhurnal [Russian Journal of Oncology], 2002, 3. pp. 39–44.
13. Dvorak H. F. Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumour angiogenesis and a potential target for diagnosis and therapy. J. Clin. Oncol. 2002, 20, pp. 4368–4380.
14. Fidler I. J. The biology of cancer metastasis and implications for therapy // Curr Probl Surg, 1987, 24. pp. 129-209.
15. Gomes F. G., Nedel F., Alves A. M., Nor J. E., Tarquinio S. B. Tumor angiogenesis and lymphangiogenesis: tumor endothelial crosstalk and cellular microenvironmental signaling mechanisms. Life Sci. 2013, 2, pp. 101–107.
16. Lauria R., Perrone F., Carlomagno C., De Laurentiis M. et al. The prognostic value of lymphatic and blood vessel invasion in operable breast cancer. Cancer. 1995, 76, pp. 1772-1778.
17. Schoppmann S. F., Horvat R., Birner P. Lymphatic vessels and lymphangiogenesis in female cancer: mechanisms, clinical impact and possible implications for anti-lymphangiogenic therapies (Review). Oncol. Rep. 2002, 9. pp. 455–460.
18. Sporn M. B. The war on cancer. Lancet. 1996, 347. pp. 1377-1381.
19. Swartz M., Lund A. Lymphatic and interstitial flow in the tumour microenvironment: linking mechanobiology with immunity. Nature. 2012, 12, pp. 210–219.
20. Weitman E., Cuzzone D., Mehrara B.J. Tissue engineering and regeneration of lymphatic structures. Future Oncol. 2013, 9, pp.1365-1374.
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Gantsev Sh. Kh., Kzyrgalin Sh. R., Kayumova A. N. Restructuring regularities of axillary area limphatic vessels in breast cancer. Nauka i Zdravoohranenie [Science & Healthcare]. 2015, 6, pp. 92-100.Related publications:
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