PROGNOSTIC VALUE OF THE RATIO OF NEUTROPHILS TO LYMPHOCYTES IN ELDERLY PATIENTS WITH ACUTE CORONARY SYNDROME WITHOUT ST ELEVATION
coronary heart disease and left ventricular systolic dysfunction of any degree in the group of elderly patients admitted to the emergency department with acute coronary syndrome (ACS) without raising the ST segment.
Objective: to assess the predictive role of NLR in relation to the severity of ACS without ST elevation in case of single or multiple damage of coronary vessels and LV dysfunction in elderly patients.
Methods: we included 106 patients aged ≥60 years with ACS without ST segment elevation who underwent coronary angiography from January to June 2019. The main study group included 56 patients with severe [> 50%] lesions of one or more epicardial arteries or branches; the comparison group included 50 patients with coronary artery disease in the absence of serious coronary artery lesions. A comparison of key clinical parameters in the study groups was carried out, while the NLR indicator predicted the severity of coronary heart disease and left ventricular systolic dysfunction of any degree. Study design is transverse. Statistical processing: IBM SPSS Statistics 20, with the determination of the normality of the distribution of the studied characteristics and the assessment of descriptive statistics of numerical variables. Qualitative variables are presented as absolute numbers and their percentages.
Results. An analysis of the results of laboratory and instrumental examination of patients with ACS without ST elevation, included in the study groups, indicates that in the main group with more pronounced ischemic damage to myocardial tissues, which was confirmed by echocardiography, a study of the level of troponin, the NLR rate was also significantly higher. than in the comparison group. This indicates a more pronounced inflammation in the heart muscle of the individuals of the main group.
Conclusion: NLR is a simple, fast, and low-cost parameter that can predict the severity of IHD and left ventricular systolic dysfunction in elderly patients with ACS without ST segment elevation.
Diana G. Igieva1,
Lyudmila M. Pivina1, https://orcid.org/0000-0002-8035-4866
Gulnara B. Batenova1,
Meiramgyl O. Tokbulatova1
1 NPJSC "Semey Medical University",
Semey, Republic of Kazakhstan
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Igieva D.G., Pivina L.M., Batenova G.B., Tokbulatova M.O. Prognostic value of the ratio of neutrophils to lymphocytes in elderly patients with acute coronary syndrome without ST elevation // Nauka i Zdravookhranenie [Science & Healthcare]. 2020, (Vol.22) 2, pp. 79-85. DOI 10.34689/SH.2020.22.2.009Related publications:
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