RISK FACTORS OF PREECLAMPSIA IN WOMEN OF SEMEY CITY, EAST-KAZAKHSTAN REGION
Background. Preeclampsia and eclampsia is a generalized, multi-factorial and long-term process that can develop during all periods of pregnancy.
The objective of the study was to define the predictors of preeclampsia in women living in Semey city.
Materials and Methods. This is observational cohort study. Included patients were those having a burdened obstetric history. Data are presented as absolute data and percentage, and also the means, standard deviation 95% CI. Pearson's Chi-square (2) test was used to check a statistical relationship between variables.
Results. The average gestation period was 38.3 (±3.61) weeks. Preeclampsia was diagnosed in 3.2% (n=6) of the study participants. The average age of women with preeclampsia was 34.3 (±3.72) years. The study revealed a statistically significant relationship with age (p=0.015), nationality (p=0.046), the presence of chronic hypertension (p=0.001), presence of interval between pregnancy (p=0.034), a history of Dopegit intake (p=0.014), and the development of preeclampsia.
Conclusion. In this study age, nationality, preeclampsia, gestational hypertension or eclampsia in history, the presence of interval between previous pregnancy, and a history of Dopegit intake were the risk factors for Semey city population.
Alima S. Nurgazina1, https://orcid.org/0000-0003-1023-8496
Nadira S. Slyamkhanova1, https://orcid.org/0000-0003-3874-1309
Gulnar M.Shalgumbayeva1, http://orcid.org/0000-0003-3310-4490
1 NPJSC "Semey Medical University",
Semey, Republic of Kazakhstan
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22. Carolan M. Maternal age ≥45 years and maternal and perinatal outcomes: a review of the evidence. // Midwifery. 2013; 29:479–89.
23. Chen X.K., Wen S.W., Fleming N., Demissie K., Rhoads G.G., Walker M. Teenage pregnancy and adverse birth outcomes: a large population based retrospective cohort study. Int J Epidemiol. 2007; 36:368–73.
24. Clivaz Mariotti L., Saudan P., Landau Cahana R., Pechere–Bertschi A. Hypertension in pregnancy. Rev. Med. Suisse. 2007; 3(124): P. 2015–2016
25. Curiel-Balsera E., Prieto-Palomino M.A., Mu'noz-Bono J, Ruiz de Elvira MJ, Galeas JL, Quesada García G. Analysis of maternal morbidity and mortality among patients admitted to obstetric intensive care with severe preeclampsia, eclampsia or HELLP syndrome. Med Intensiva. 2011; 35(8): 478483. PubMed |Google Scholar
26. Dietl A., Cupisti S., Beckmann M.W., Schwab M, Zollner U. Pregnancy and obstetrical outcomes in women over 40 years of age. Geburtshilfe Frauenheilkd. 2015;75:827–32.
27. Gibbs C.M., Wendt A., Peters S. The impact of early age at first childbirth on maternal and infant health. Paediatr Perinat Epidemiol. 2012; 26 (Suppl 1):259-84.
28. Goffinet F. Epidemiology. Ann Fr Anesth Reanim. 2010; 29(3): 7-12. [PubMed.]
29. Hamilton B.E., Martin J.A., Osterman M.J., Curtin S.C., Matthews T.J. Births: final data for 2014. Natl Vital Stat Rep. 2015; 64:1–64
30. Harioly N., Rasolonjatovo T.Y., Randriambololona A.M., Ranoaritiana D.B., Andrianjatovo J.J., Randriamiarana J.M. Profil épidémiologique des pré-éclampsies et des éclampsies admises à la réanimation des adultes de la maternité de Befelatanana. Rev Anest Réa Méd Urg. 2009; 1(3): 22-24.
31. Huang L., Sauve R., Birkett N., Fergusson D., van Walraven C. Maternal age and risk of stillbirth: a systematic review. CMAJ. 2008;178:165-72
32. Jolly M., Sebire N., Harris J., Robinson S., Regan L. The risks associated with pregnancy in women aged 35 years or older. Hum Reprod. 2000; 15:2433-7.
33. Kanungo J., James A., McMillan D., Lodha A., Faucher D., Lee S.K., et al. Advanced maternal age and the outcomes of preterm neonates: a social paradox? Obstet Gynecol. 2011; 118:872-7.
34. Kenny L.C., Lavender T., McNamee R.. O’Neill S.M., Mills T., Khashan A.S. Advanced maternal age and adverse pregnancy outcome: evidence from a large contemporary cohort. PLoS One. 2013;8:e56583.
35. Khalil A., Syngelaki A., Maiz N., Zinevich Y., Maternal age and adverse pregnancy outcome: a cohort study. Ultrasound Obstet Gynecol. 2013; 42:634–43.
36. Laopaiboon M., Lumbiganon P., Intarut N., Mori R., Ganchimeg T., Vogel J.P., et al. Advanced maternal age and pregnancy outcomes: a multicountry assessment. BJOG. 2014;121 (Suppl 1):49–56
37. Loghi M., Crialesi R. La salute riproduttiva della donna. Roma: Istituto Nazionale di Statistica. 2017. 115p.
38. Londero A.P., Bertozzi S., Fruscalzo A., Driul L., Marchesoni D. Ultrasonographic assessment of cervix size and its correlation with female characteristics, pregnancy, bmi, and other anthropometric features. Arch Gynecol Obstet. 2011; 283:545-50.
39. Londero A.P., Rossetti E, Pittini C., Cagnacci A., Driul L. Maternal age and the risk of adverse pregnancy outcomes: a retrospective cohort study. BMC Pregnancy and Childbirth. 2019; 19:261 https://doi.org/10.1186/s12884-019-2400-x
40. Magee L.A., Ornstein M.P., von Dadelszen P. Fortnightly review: management of hypertension in pregnancy. BMJ. 1999; 318 (7194):1332-6
41. Malabarey O.T., Balayla J., Klam S.L., Shrim A., Abenhaim H.A. Pregnancies in young adolescent mothers: a population-based study on 37 million births. J Pediatr Adolesc Gynecol. 2012;25:98–102
42. .Mulla Z. D., Nuwayhid B. S., Garcia K. M. et al. Risk factors for a prolonged length of stay in women hospitalized for preeclampsia in Texas. Hypertens Pregnancy. 2010; 29 (1): 54–68.
43. Muntner P., Bowling C.B., Shimbo D. Systolic blood pressure goals to reduce cardiovascular disease among older adults. Am J Med Sci. 2014;348 (2):129-34
44. Poon LC, Shennan A, Hyett JA, et al. The International Federation of Gynecology and Obstetrics (FIGO) initiative on pre-eclampsia: a pragmatic guide for first-trimester screening and prevention. Int J Gynaecol Obstet. 2019; 145 (suppl 1): 1–33.
45. Ramakrishnan A, Lee L.J., Mitchell L.E., Agopian A.J. Maternal hypertension during pregnancy and the risk of congenital heart defects in offspring: a systematic review and meta-analysis. Pediatr Cardiol. 2015;36 (7):1442-51
46. Shan D., Qiu P.Y., Wu Y.X., Chen Q., Li A.L., Ramadoss S., et al. Pregnancy outcomes in women of advanced maternal age: a retrospective cohort study from China. Sci Rep. 2018; 8:12239
47. Sibai B.M. Chronic hypertension in pregnancy. Obstet Gynecol. 2002; 100 (2):369-77.
48. Sibai BM. Treatment of hypertension in pregnant women. N Engl J Med. 1996; 335 (4):257-65
49. Sibai B.M., Caritas S.N., Hauth J.C., MacPherson C., VanDorsten J.P., Klebanoff M., et al. Preterm delivery in women with pregestational diabetes mellitus or chronic hypertension relative to women with uncomplicated pregnancies. The National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. Am J Obstet Gynecol. 2000; 183 (6):1520-4.
50. Sobotka T. Post-transitional fertility: childbearing postponement and the shift to low and unstable fertility levels. Vienna: Vienna Institute of Demography Working Papers 01. 2017.
51. Wang Y., Tanbo T., Abyholm T., Henriksen T. The impact of advanced maternal age and parity on obstetric and perinatal outcomes in singleton gestations. Arch Gynecol Obstet. 2011; 284:31–7.
52. Waters E.G., Wager H.P. Pregnancy and labour experiences of elderly primigravidas. J Mich State Med Soc. 1950; 49:435–9.
53. Winer N., Tsasaris V. État des connaissances: prise en charge thérapeutique de la pré-éclampsie. J Gynecol Obstet Biol Reprod. 2008; 37 (1): 5-15
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Bibliography link
Nurgazina A.S., Slyamkhanova N.S., Shalgumbayeva G.M. Risk factors of preeclampsia in women of Semey city, East-Kazakhstan region // Nauka i Zdravookhranenie [Science & Healthcare]. 2020, (Vol.22) 2, pp. 109-117. doi 10.34689/SH.2020.22.2.013Related publications:
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