THE ROLE OF CYTOKINE GENE POLYMORPHISMS IN BACTERIAL INFECTIONS, INCLUDING BRUCELLOSIS. LITERATURE REVIEW
Relevance. Studies conducted to date have shown the presence of associations of gene polymorphisms of a number of cytokines with a predisposition or resistance to the development of many infectious diseases.
Aim. This review is devoted to the analysis of literature on the association of cytokine gene polymorphisms in infectious diseases of bacterial origin, in particular, with brucellosis.
Search strategy. Search of scientific publications in the search engines Pub Med, Google Scholar, Google Academia, in the electronic scientific library eLibrary.ru, CyberLeninka 10 years deep. Criteria for search information: years of search included one decade (2008-2018); publications were in Russian, Kazakh and English; full-textured epidemiological and clinical studies. Exclusion criteria: publications with animal studies, recurring publications, conference proceedings, and clinical cases.
Results. An analysis of literature showed that bacterial infections such as tuberculosis, erysipelas and brucellosis are most often associated with polymorphisms of genes of the following cytokines: TNF-α, IL-10, IL-1β, IL-17A, IL-6.The results of the analysis also showed that the same polymorphisms in different ethnic groups can be associated with both predisposition and resistance. Polymorphisms of the IL-6, IL-10, and IL-17 genes were more often associated with brucellosis.
Conclusion. Thus, such studies must be carried out in a certain population of people of the same nationality.
Lidia A. Mukovozova1,
Nazira B. Bekenova1, http://orcid.org/0000-0002-3312-3299
Alma Z. Tokaeva1, Yerbol M. Smail1
1 NJSC «Semey Medical University», Semey, Republic of Kazakhstan.
1. Бекенова Н. Б., Гржибовский А.М., Муковозова Л.А., Полиморфизм гена ИЛ10 в положении -1082G/A у больных рожей // Наука и здравоохранение. 2016. № 3. С. 55-66.
2. Бекенова Н. Б., Гржибовский А.М., Муковозова Л.А., Смаил Е. М., Токаева А.З. Полиморфизм rs8193036 гена ИЛ-17А в казахской популяции и его связь с продукцией ИЛ-17А у больных рожей // Экология человека. 2016. №. 4. С.50-55.
3. Бекенова Н.Б., Муковозова Л.А., Гржибовский А.М. Ассоциация полиморфизма rs 2275913 гена ИЛ-17 А с уровнем ИЛ-17 А при роже у лиц казахской национальности // Вестник КазНМУ. 2016. № 1. С.119-122.
4. Емельянова А.Н., Витковский Ю.А., Кижло Л.Б., Калинина Э.Н. Прогностическое значение генетического полиморфизма молекул Il-2 (Т330G), Il-10 (С819Т),Il-10 (G1082A) у больных рожей в Забайкальском крае // Дальневосточный журнал инфекционной патологии. 2012. № 21. С. 159-163.
5. Ризванова Ф.Ф., Пикуза О.И., Файзуллина Р.А., Гайфуллина Р.Ф., Ризванов А.А., Кравцова О.А. Генетическая диагностика: полиморфизм генов цитокинов // Практическая медицина. 2010. №. 6. С.41-43.
6. Симбирцев А.С., Громова А.Ю. Функциональный полиморфизм генов регуляторных молекул воспаления // Цитокины и воспаление. 2005. №. 1. С.1-10.
7. Akgunes A., Coban A.Y., Durupinar B. Human leucocyte antigens and cytokine gene polymorphisms and tuberculosis // Indian journal of medical microbiology. 2011. N29(1). 28-32.
8. Areeshi M.Y., Mandal R.K., Dar S.A., Jawed A., Wahid M., Lohani M., Haque S. IL-10-1082 A>G (rs1800896) polymorphism confers susceptibility to pulmonary tuberculosis in Caucasians but not in Asians and Africans: a meta-analysis // Bioscience reports.2017. N37(5). Р. 1-17.
9. Asgharzadeh M., Ghorghanlu S., Rashedi J., Poor B.M., Khaki-Khatibi F., Moaddab S.R., Pourostadi M.Association of promoter polymorphisms of interleukin-10 and interferon-gamma genes with tuberculosis in azeri population of iran // Iranian Journal of Allergy, Asthma and Immunology. 2016. N15(3). Р.167-173.
10. Ates Ö., Musellim B., Ongen G., Topal-Sarıkaya A. Interleukin-10 and tumor necrosis factor-α gene polymorphisms in tuberculosis // Journal of clinical immunology. 2008. N28(3). Р. 232-236.
11. Bazzi M.D., Sultan M.A., Al Tassan N., Alanazi M., Al-Amri A., Al-Hajjaj M.S., Warsy A. 9 Interleukin 17A and F and Asthma in Saudi Arabia: Gene Polymorphisms and Protein Levels // Journal of Investigational Allergology and Clinical Immunology.2011.N 7.Р. 551-555.
12. Bogunia-Kubik K., Świerkot J., Malak A., Wysoczańska B., Nowak B., Białowąs K., Wiland P. IL-17A, IL-17F and IL-23R gene polymorphisms in Polish patients with rheumatoid arthritis // Archiv umimmunologi et therapi experimentalis. 2015. N3. Р. 215-221.
13. Bravo M.J., de Dios Colmenero J., Alonso A., Caballero A. Polymorphisms of the interferon gamma and interleukin 10 genes in human brucellosis // European journal of immunogenetics. 2008. N30 (6). Р. 433-435.
14. Brooks D.G., Trifilo M., Edelmann K., Teyton L., Mc. Gavern D.B., Oldstone M.B. Interleukin-10 determines viral clearance or persistence in vivo // Nature medicine. 2006. N12(11). Р. 1301-1309.
15. Budak F., Göral G., Heper Y., Yılmaz E., Aymak F., Baştürk B., Oral H. B. IL-10 and IL-6 gene polymorphisms as potential host susceptibility factors in Brucellosis // Cytokine. 2008. N38(1). Р. 32-36.
16. Ceylan E., Karkucak M., Coban H., Karadag M., Yakut T. Evaluation of TNF-alpha gene (G308A) and MBL2 gene codon 54 polymorphisms in Turkish patients with tuberculosis // Journal of infection and public health. N10(6). Р. 774-777.
17. Eskandari‐Nasab E., Moghadampour M., Sepanji-Nia A.TNF-α -238, -308, -863 Polymorphisms, and Brucellosis Infection // Human Immunology. 2016. N77(1). P.121-125.
18. Eskandari‐Nasab E., Moghadampour M., Asadi‐Saghandi A., Kharazi‐Nejad E., Rezaeifar A., Pourmasoumi H. Levels of interleukin‐(IL)‐12p40 are markedly increased in brucellosis among patients with specific IL‐12B genotypes // Scandinavian journal of immunology. 2013. N78(1). Р. 85-91.
19. Gunal O., Yigit S., Yalcın A. D., Celik B., Barut S., Demir O., Sezer O.The IL4-VNTR P1 allele, IL4-VNTR P2P2 genotype and IL4-VNTR_IL6-174CG P2P1-GG genotype are susceptable with a increased risk in Brucelosis // Japanese journal of infectious diseases.2017. N 70 (1).Р. 61-64.
20. Haukim N., Bidwell J.L., Smith A.J., Keen L.J., Gallagher G., Kimberly R., Huizinga T., McDermott M.F., Oksenberg J., McNicholl J., Pociot F., Hardt C., DAlfonso S. Cytokine gene polymorphism in human disease: on-line databases, supplement 2 // Genes and immunity. 2002. N 6. Р. 313-330.
21. Hu Y., Wu L., Li D., Zhao Q., Zhang W., Xu B. Association between cytokine gene polymorphisms and tuberculosis in a Chinese population in Shanghai: a case–control study // BMC immunology. 2015. N 16(1). P. 1-10.
22. Joshi L., Ponnana M., Sivangala R., Chelluri L.K., Nallari P., Penmetsa S., Valluri V., Gaddam S. Evaluation of TNF-α, IL-10 and IL-6 cytokine production and their correlation with genotype variants amongst tuberculosis patients and their household contacts // PloS one. 2015. N10(9). P.1-15.
23. Karaoglan I., Pehlivan S., Namiduru M., Pehlivan M., Kilinçarslan C., Balkan Y., BaydarI. TNF-alpha, TGF-beta, IL-10, IL-6 and IFN-gamma gene polymorphisms as risk factors for brucellosis // New Microbiology. 2009. N32 (2). Р. 173-8.
24. Karaoglan I., Pehlivan S., Namiduru M., Pehlivan M., Kilinçarslan C., Balkan Y., Baydar I. TNF-alpha, TGF-beta, IL-10, IL-6 and IFN-gamma gene polymorphisms as risk factors for brucellosis // New Microbiology. 2009. N32 (2). Р. 173-8.
25. Kazemi S., Saidijam M., Hashemi S. H., Karami M., Vaisi-Raygani A., Alikhani M. Y. Analysis of IL-10 and IL-6 gene polymorphisms and their serum levels in patients with brucellosis: a case control study // Immunological investigations. 2016. N45(2). P. 107-115.
26. McGuire W., Hill A.V., Allsopp C.E., Greenwood B.M, Kwiatkowski D. Variation in the TNF-α promoter region associated with susceptibility to cerebral malaria // Nature. 1994. N 371(6497). P. 508-511.
27. Meenakshi P., Ramya S., Shruthi T., Lavanya J., Mohammed H.H., Vijayalakshmi V., Sumanlatha G. Association of IL‐1β+ 3954 C/T and IL‐10‐1082 G/A Cytokine Gene Polymorphisms with Susceptibility to Tuberculosis // Scandinavian journal of immunology. 2013. N 78(1). Р. 92-97.
28. Mira J.P, Cariou A., Grall F., Delclaux C., Losser M.R., Heshmati F., Cheval C., Monchi M., Teboul J.L., Riché F., Leleu G., Arbibe L., Mignon A., Delpech M., Dhainaut J.F. Association of TNF2, a TNF-α promoter polymorphism, with septic shock susceptibility and mortality: a multicenter study // Jama. 1999. N 282(6). Р. 561-568.
29. Mosaad Y.M., Soliman O.E., Tawhid Z.E., Sherif D.M. Interferon‐gamma+ 874 T/A and Interleukin‐10‐1082 A/G Single nucleotide Polymorphism in Egyptian Children with Tuberculosis // Scandinavian journal of immunology. 2010. N 72(4). P. 358-364.
30. Nadel S., Newport M.J., Booy R., Levin M. Variation in the tumor necrosis factor-α gene promoter region may be associated with death from meningococcal disease // Journal of Infectious Diseases. 1996. N 174(4). Р. 878-880.
31. Ocejo-Vinyals J., de Mateo E., Hoz M. The IL-17 G-152A single nucleotide polymorphism is associated with pulmonary tuberculosis in northern Spain // Cytokine. 2013. N 1. Р.58–61.
32. Pacheco A.G., Moraes M.O. Genetic polymorphisms of infectious diseases in case-control studies // Disease markers. 2009. N 27. N3-4. Р. 173-186.
33. Prieto-Pérez R., Cabaleiro T., Dauden E., Abad-Santos F. Gene polymorphisms that can predict response to anti-TNF therapy in patients with psoriasis and related autoimmune diseases // The pharmacogenomics journal. 2013. N13(4). 297-305.
34. Rasouli M., Kalani M., Moravej A., Kiany S.Interleukin-18 single nucleotide polymorphisms contribute to the susceptibility to brucellosis in Iranian patients // Cytokine.2011. N. 54 (3). Р. 272-276.
35. RasouliM., Kiany S., Behbin M. Interleukin-10 gene polymorphisms and susceptibility to brucellosis in Iranian patients // Iranian journal of immunology. 2008. N5 (2). Р. 131-135.
36. Rasouli M., Kiany S. Association of interferon-gamma and interleukin-4 gene polymorphisms with susceptibility to brucellosis in Iranian patients // Cytokine. 2008. N38 (1). Р. 49-53.
37. Rasouli M., Asaei S., Kalani M., Kiany S., Moravej A. Interleukin-17A genetic variants can confer resistance to brucellosis in Iranian population // Cytokine. 2013. N61(1). Р. 297-303.
38. Shen L., Zhang H., Yan T., Zhou G., Liu R. Association between interleukin 17A polymorphisms and susceptibility to rheumatoid arthritis in a Chinese population // Gene.2015. N1. Р.18-22.
39. Stappers M., Thys Y., Oosting M., Plantinga T., Ioana M., Reimnitz P., Mouton J., Netea M., Joosten L.. Polymorphisms in cytokine genes IL6, TNF, IL10, IL17A and IFNG influence susceptibility to complicated skin and skin structure infections // European Journal of Clinical Microbiology & Infectious Diseases. 2014. N 33(12). P 2267-2274.
40. Tarhuni A., GuyotE., Rufat P., Sutton A., Bourcier V., Grando V., Moreau R. Impact of cytokine gene variants on the prediction and prognosis of hepatocellular carcinoma in patients with cirrhosis // Journal of hepatology. 2014. N 2. Р. 342-350.
41. Tunçbilek S. Relationship between cytokine gene polymorphisms and chronic hepatitis B virus infection // World journal of gastroenterology: WJG. 2014. N 20. Р. 6226-6235.
42. Wu S., Wang Y., Zhang M., Shrestha S.S., Wang M., He J.Q. Genetic Polymorphisms of IL1B, IL6, and TNFα in a Chinese Han Population with Pulmonary Tuberculosis // BioMed research international. 2018. N33(12). Р. 1-10.
43. Xavier M.N., Winter M.G., Spees A.M., Nguyen K., Atluri V.L., Silva T.M., Tsolis R.M. CD4+ T cell-derived IL-10 promotes Brucellaabortus persistence via modulation of macrophage function // PLoS pathogens. 2013. N. 9 (6). Р. 1-17.
44. Yee L.J., Tang J., Herrera J., Kaslow R.A., van Leeuwen D.J. Tumor necrosis factor gene polymorphisms in patients with cirrhosis from chronic hepatitis C virus infection // Genes and immunity. 2000. N 1(6). Р. 386-390.
45. Zhang G., Zhou B., Li S., Yue J., Yang H., Wen Y., Zeng G. Allele-specific induction of IL-1β expression by C/EBPβ and PU. 1 contributes to increased tuberculosis susceptibility //PLoSPathog. 2014. N 10. Р.1-15.
46. Zhao J., Wen C., Li M. Association analysis of Interleukin-17 gene polymorphisms with the risk susceptibility to tuberculosis // Lung.2016. N 194(3). Р. 459-467.
References:
1. Bekenova N.B., Grzhibovskij A.M., Mukovozova L.A. Polimorfizm gen aIL10 v polozhenii - 1082G/A u bol'nykh rozhei [Polymorphism of IL10 gene at-1082G/A position in patients with erysipelas]. Nauka I zdravookhranenie [Science & Healthcare]. 2016. No. 3. pp. 55-66. [in Russian]
2. Bekenova N.B., Grjibovski A.M., Mukovozova L.A., Smail E.M., Tokaeva A.Z. Polimorfizm rs8193036 gen aIL-17A v kazakhskoi populyatsiii ego svyaz' s produktsiei IL-17A u bol'nykh rozhei [rs8193036 polymorphism of IL-17A gene in a Kazakh population and its association with plasma IL-17A among erysipelas patients]. Ekologiya cheloveka [Human Ecology]. 2016. No. 4. pp.50-55. [in Russian]
3. Bekenova N.B., Mukovozova L.A., Grzhibovskij A.M. Assotsiatsiya polimorfizma rs 2275913 gena IL-17 A s urovnem IL-17 A pri rozhe u lits kazakhskoi natsional'nosti [Associations of gene polymorphism of IL-17 A rs2275913 with its level in patients with erysipelas kazakh population]. Vestnik Kaz NMU [Bulletin of KazNMU]. 2016. No 1. pp.119-122.
4. Emel'yanova A.N., VitkovskiiYu.A., Kizhlo L.B., Kalinina E.N. Prognosticheskoe znachenie geneticheskogo polimorfizma molekul Il-2 (T330G), Il-10 (S819T), Il-10 (G1082A) u bol'nykh rozhei v Zabaikal'skom krae [Prognostic significance of geneticpolymorphismofIL-2 (T330G), IL-10 (C819T), IL-10 (G1082A) in patients with erysipelas in Transbaikal region] Dal'nevostochnyi zhurnal infektsionnoi patologii [Far Eastern Journal of Infectious Pathology]. 2012. No 21. pp. 159-163. [in Russian]
5. Rizvanova F.F., Pikuza O.I., Faizullina R.A., Gaifullina R.F., Rizvanov A.A., Kravtsova O.A. Geneticheskaya diagnostika: polimorfizm genov tsitokinov [Genetic diagnosis: polymorphism of cytokine genes]. Prakticheskaya meditsina [Practical medicine]. 2010. No.6. pp.41-43.
6. Simbirtsev A.S., Gromova A.Yu. Funktsional'nyi polimorfizmgenovregulyatornykhmolekulvospaleniya [Functional gene polymorphisms of the molecules regulating inflammation] Tsitokiny I vospalenie. [Cytokines and inflammation] 2005. No 1. PP. 3-10. [in Russian]
7. Akgunes A., Coban A.Y., Durupinar B. Human leucocyte antigens and cytokine gene polymorphisms and tuberculosis. Indian journal of medical microbiology. 2011. 29(1). pp. 28-32.
8. Areeshi M.Y., Mandal R.K., Dar S.A., Jawed A., Wahid M., Lohani M., Haque S. IL-10-1082 A> G (rs1800896) polymorphism confers susceptibility to pulmonary tuberculosis in Caucasians but not in Asians and Africans: a meta-analysis. Bioscience reports. 2017. 37(5). pp. 1-17.
9. Asgharzadeh M., Ghorghanlu S., Rashedi J., Poor B.M., Khaki-Khatibi F., Moaddab S.R., Pourostadi M. Association of promoter polymorphisms of interleukin-10 and interferon-gamma genes with tuberculosis in azeri population of iran. Iranian Journal of Allergy, Asthma and Immunology. 2016. 15(3). pp.167-173.
10. Ates Ö., Musellim B., Ongen G., Topal-Sarıkaya A. Interleukin-10 and tumor necrosis factor-α gene polymorphisms in tuberculosis. Journal of clinical immunology. 2008. 28(3). pp. 232-236.
11. Bazzi M.D., Sultan M.A., Al Tassan N., Alanazi M., Al-Amri A., Al-Hajjaj M.S., Warsy A. 9 Interleukin 17A and F and Asthma in Saudi Arabia: Gene Polymorphisms and Protein Levels. Journal of Investigational Allergology and Clinical Immunology. 2011. 7. pp. 551-555.
12. Bogunia-Kubik K., Świerkot J., Malak A., Wysoczańska B., Nowak B., Białowąs K., Wiland P. IL-17A, IL-17F and IL-23R gene polymorphisms in Polish patients with rheumatoid arthritis. Archiv umimmunologi et therapy experimentalis. 2015. 3. pp.215-221.
13. Bravo M.J., de Dios Colmenero J., Alonso A., Caballero A. Polymorphisms of the interferon gamma and interleukin 10 genes in human brucellosis. European journal of immunogenetics. 2008.30 (6). pp. 433-435.
14. Brooks D.G., Trifilo M., Edelmann K., Teyton L., Mc. Gavern D.B., Oldstone M.B.Interleukin-10 determines viral clearance or persistence in vivo. Nature medicine. 2006. 12(11). pp. 1301-1309.
15. Budak F., Göral G., Heper Y., Yılmaz E., Aymak F., Baştürk B., Oral H. B. IL-10 and IL-6 gene polymorphisms as potential host susceptibility factors in Brucellosis. Cytokine. 2008. 38(1). pp. 32-36.
16. Ceylan E., Karkucak M., Coban H., Karadag M., Yakut T. Evaluation of TNF-alpha gene (G308A) and MBL2 gene codon 54 polymorphisms in Turkish patients with tuberculosis. Journal of infection and public health. 10(6). pp. 774-777.
17. Eskandari‐Nasab E., Moghadampour M., Sepanji-Nia A. TNF-α -238, -308, -863 Polymorphisms and Brucellosis Infection. Human Immunology. 2016. 77(1). pp.121-125.
18. Eskandari‐Nasab E., Moghadampour M., Asadi‐Saghandi A., Kharazi‐Nejad E., Rezaeifar A., Pourmasoumi H. Levels of interleukin‐(IL)‐12p40 are markedly increased in brucellosis among patients with specific IL‐12B genotypes. Scandinavian journal of immunology. 2013. 78(1). pp. 85-91.
19. Gunal O., Yigit S., Yalcın A.D., Celik B., Barut S., Demir O., Sezer O.The IL4-VNTR P1 allele, IL4-VNTR P2P2 genotype and IL4-VNTR_IL6-174CG P2P1-GG genotype are susceptable with a increased risk in Brucelosis. Japanese journal of infectious diseases. 2017. 70 (1).pp. 61-64.
20. Haukim N., Bidwell J.L., Smith A.J., Keen L.J., Gallagher G., Kimberly R., Huizinga T., McDermott M.F., Oksenberg J., McNicholl J., Pociot F., Hardt C., DAlfonso S. Cytokine gene polymorphism in human disease: on-line databases, supplement 2. Genes and immunity. 2002. 6. pp. 313-330.
21. Hu Y., Wu L., Li D., Zhao Q., Zhang W., Xu B. Association between cytokine gene polymorphisms and tuberculosis in a Chinese population in Shanghai: a case–control study. BMC immunology. 2015. 16(1). pp. 1-10.
22. Joshi L., Ponnana M., Sivangala R., Chelluri L.K., Nallari P., Penmetsa S., Valluri V., Gaddam S. Evaluation of TNF-α, IL-10 and IL-6 cytokine production and their correlation with genotype variants amongst tuberculosis patients and their household contacts. PloS one. 2015. 10(9). pp.1-15.
23. Karaoglan I., Pehlivan S., Namiduru M., Pehlivan M., Kilinçarslan C., Balkan Y., Baydar I. TNF-alpha, TGF-beta, IL-10, IL-6 and IFN-gamma gene polymorphisms as risk factors for brucellosis. New Microbiology. 2009. 32 (2). pp. 173-8.
24. Karaoglan I., Pehlivan S., Namiduru M., Pehlivan M., Kilinçarslan C., Balkan Y., Baydar I.TNF-alpha, TGF-beta, IL-10, IL-6 and IFN-gamma gene polymorphisms as risk factors for brucellosis. New Microbiology. 2009.32 (2). pp. 173-8.
25. Kazemi S., Saidijam M., Hashemi S. H., Karami M., Vaisi-Raygani A., Alikhani M.Y. Analysis of IL-10 and IL-6 gene polymorphisms and their serum levels in patients with brucellosis: a case control study. Immunological investigations. 2016. 45(2). pp. 107-115.
26. McGuire W., Hill A.V., Allsopp C.E., Greenwood B.M., Kwiatkowski D. Variation in the TNF-α promoter region associated with susceptibility to cerebral malaria. Nature. 1994.371(6497). pp. 508-511.
27. Meenakshi P., Ramya S, Shruthi T, Lavanya J, Mohammed H.H., Vijayalakshmi V, Sumanlatha G. Association of IL‐1β+ 3954 C/T and IL‐10‐1082 G/A Cytokine Gene Polymorphisms with Susceptibility to Tuberculosis. Scandinavian journal of immunology. 2013. 78(1). pp. 92-97.
28. Mira J.P., Cariou A., Grall F., Delclaux C., Losser M.R., Heshmati F., Cheval C., Monchi M., Teboul J.L., Riché F., Leleu G., Arbibe L., Mignon A., Delpech M., Dhainaut J.F. Association of TNF2, a TNF-α promoter polymorphism, with septic shock susceptibility and mortality: a multicenter study. Jama. 1999. 282(6). pp. 561-568.
29. Mosaad Y.M., Soliman O.E., Tawhid Z.E., Sherif D.M. Interferon‐gamma+ 874 T/A and Interleukin‐10‐1082 A/G Single nucleotide Polymorphism in Egyptian Children with Tuberculosis. Scandinavian journal of immunology. 2010. 72(4). pp. 358-364.
30. Nadel S., Newport M.J., Booy R., Levin M. Variation in the tumor necrosis factor-α gene promoter region may be associated with death from meningococcal disease. Journal of Infectious Diseases. 1996. 174(4). pp. 878-880.
31. Ocejo-Vinyals J., de Mateo E., Hoz M. The IL-17 G-152A single nucleotide polymorphism is associated with pulmonary tuberculosis in northern Spain. Cytokine. 2013.1. pp.58–61.
32. Pacheco A.G., Moraes M.O. Genetic polymorphisms of infectious diseases in case-control studies. Disease markers. 2009. 27. pp. 173-186.
33. Prieto-Pérez R., Cabaleiro T., Dauden E., Abad-Santos F. Gene polymorphisms that can predict response to anti-TNF therapy in patients with psoriasis and related autoimmune diseases. The pharmacogenomics journal. 2013. 13(4). pp. 297-305.
34. Rasouli M., Kalani M., Moravej A., Kiany S. Interleukin-18 single nucleotide polymorphisms contribute to the susceptibility to brucellosis in Iranian patients. Cytokine. 2011. 54 (3). pp. 272-276.
35. Rasouli M., Kiany S., Behbin M. Interleukin-10 gene polymorphisms and susceptibility to brucellosis in Iranian patients. Iranian journal of immunology. 2008. 5 (2). pp. 131-135.
36. Rasouli M., Kiany S. Association of interferon-gamma and interleukin-4 gene polymorphisms with susceptibility to brucellosis in Iranian patients. Cytokine. 2008. 38 (1). pp. 49-53.
37. Rasouli M., Asaei S., Kalani M., Kiany S., Moravej A. Interleukin-17A genetic variants can confer resistance to brucellosis in Iranian population. Cytokine. 2013. 61(1). pp. 297-303.
38. Shen L., Zhang H., Yan T., Zhou G., Liu R. Association between interleukin 17A polymorphisms and susceptibility to rheumatoid arthritis in a Chinese population. Gene. 2015. 1. pp.18-22.
39. Stappers M., Thys Y., Oosting M., Plantinga T., Ioana M., Reimnitz P., Mouton J., Netea M., Joosten L. Polymorphisms in cytokine genes IL6, TNF, IL10, IL17A and IFNG influence susceptibility to complicated skin and skin structure infections. European Journal of Clinical Microbiology & Infectious Diseases. 2014. 33(12). pp. 2267-2274.
40. Tarhuni A., Guyot E., Rufat P., Sutton A., Bourcier V., Grando V., Moreau R.Impact of cytokine gene variants on the prediction and prognosis of hepatocellular carcinoma in patients with cirrhosis. Journal of hepatology. 2014. 2. pp. 342-350.
41. Tunçbilek S. Relationship between cytokine gene polymorphisms and chronic hepatitis B virus infection. World journal of gastroenterology: WJG. 2014. 20. pp. 6226-6235.
42. Wu S., Wang Y., Zhang M., Shrestha S.S., Wang M., He J.Q. Genetic Polymorphisms of IL1B, IL6, and TNFα in a Chinese Han Population with Pulmonary Tuberculosis. BioMed research international.2018. 33(12).pp. 1-10.
43. Xavier M.N., Winter M.G., Spees A.M., Nguyen K., Atluri V.L., Silva T.M., Tsolis R.M. CD4+ T cell-derived IL-10 promotes Brucellaabortus persistence via modulation of macrophage function. PLoS pathogens. 2013.9 (6). рр. 1-17.
44. Yee L.J., Tang J., Herrera J., Kaslow R.A., van Leeuwen D.J. Tumor necrosis factor gene polymorphisms in patients with cirrhosis from chronic hepatitis C virus infection. Genes and immunity. 2000.1(6). рр. 386-390.
45. Zhang G., Zhou B., Li S., Yue J., Yang H., Wen Y., Zeng G. Allele-specific induction of IL-1β expression by C/EBPβ and PU. 1 contributes to increased tuberculosis susceptibility. PLoSPathog. 2014.10. рр.1-15.
46. Zhao J., Wen C., Li M. Association analysis of Interleukin-17 gene polymorphisms with the risk susceptibility to tuberculosis. Lung. 2016. 194(3). рр. 459-467.
Number of Views: 224
Category of articles:
Reviews
Bibliography link
Mukovozova L.A., Bekenova N.B., Tokaeva A.Z., SmailYe.M. The role of cytokine gene polymorphisms in bacterial infections, including brucellosis. Literature review // Nauka i Zdravookhranenie [Science & Healthcare]. 2020, 5 (Vol.22), pp. 47-56. doi:10.34689/SH.2020.22.5.004Related publications:
INTERRELATION OF INTRAABDOMINAL HYPERTENSION AND MARKERS OF GASTROINTESTINAL TRACT INJURY IN PATIENTS WITH MULTIORGAN DYSFUNCTION
DRUG-INDUCED LIVER INJURY AND GENDER DIFFERENCES
QUALITY OF LIFE IN PRIMARY BILIARY CHOLANGITIS AND ITS ASSESSMENT
DIAGNOSTIC AND THERAPEUTIC LAPAROSCOPY FOR ABDOMINAL INJURIES. REVIEW
METHODS FOR SCHOOL-AGE CHILDREN NUTRITIONAL STATUS ASSESSMENT: FOCUS ON ANTHROPOMETRIC PARAMETERS. A REVIEW.