A CLINICAL CASE OF PULMONARY SARCOIDOSIS IN A PATIENT WITH CANCER
The planned fluorographic examination of the chest organs was starting point of the diagnostic process. The complexity of this clinical case is due to the fact that the results of PET combined with CT of the lungs in combination with anamnestic data were interpreted as a cancer process in the lungs with metastasis. However, the absence of a clinical picture of the oncological process, such as a “с alm” laboratory parameter initiated an in-depth examination with morphological verification of the diagnosis (the method of obtaining the material was transbronchial biopsy of the lungs and intrathoracic lymph nodes). In addition, the prescribed therapy with systemic glucocorticoids improved the patient's condition and previous radiological changes. This case demonstrates the significance of individual (personalized) approach in the diagnosis and treatment of sarcoidosis.
Madina A. Yessengeldinova 1,2, https://orcid.org/0000-0002-7348-4400
Roza A. Bakenova 2, https://orcid.org/0000-0002-5024-9096
Telman Z. Seisembekov1, https://orcid.org/0000-0002-2129-7128
1 Astana Medical University, Nur-Sultan, The Republic of Kazakhstan;
2 Hospital of the Presidential Administration Medical Center, Nur-Sultan, The Republic of Kazakhstan
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11. Fidler L.M. et al. Epidemiology and health outcomes of sarcoidosis in a universal healthcare population: a cohort study. Eur. Respir. J. 2019. Т. 54. № 4. С. 1–9.
12. Goyal Abhishek; Gupta Dheeraj; Ritesh Aggarwal Bal Amanjit; Raje Nijhawan, Aggarwal A.N. Value of Different Bronchoscopic Sampling Techniques in Diagnosis of Sarcoidosis. J. Bronchology Interv. Pulmonol. 2014. Т. 21. № 3. С. 220–226.
13. Grunewald J. et al. Sarcoidosis. Nat. Rev. Dis. Prim. 2019. Т. 5. № 1. С. 45.
14. James D.G. Sarcoidosis 2001. Postgrad. Med. J. 2001. Т. 77. № 905. С. 177–180.
15. Judson M. The diagnosis of sarcoidosis. Clin. Chest. Med. 2008. Т. V.29. С. Р.415-427.
16. Keijsers R.G.M., Grutters J.C. In Which Patients with Sarcoidosis Is FDG PET/CT Indicated? J. Clin. Med. 2020. Т. 9. № 3. С. 890.
17. Newman L.S. et al. A case control etiologic study of sarcoidosis: Environmental and occupational risk factors. Am. J. Respir. Crit. Care Med. 2004. Т. 170. № 12. С. 1324–1330.
18. Roszkiewicz J., Smolewska E. Kaleidoscope of autoimmune diseases in HIV infection. Rheumatol. Int. 2016. Т. 36. № 11. С. 1481–1491.
19. Salah S., Abad S., Monnet D., Brézin A.P. Sarcoidosis. J. Fr. Ophtalmol. 2018. Т. 41. № 10. С. 451–467.
20. Soto-Gomez N., Peters J.I., Nambiar A.M. Diagnosis and Management of Sarcoidosis, 2016. pp. 1–11.
21. Ungprasert P. et al. Epidemiology of Sarcoidosis 1946-2013: A Population-Based Study. Mayo Clin. Proc. 2016. Т. 91. № 2. С. 183–188.
22. Ungprasert P., Ryu J.H., Matteson E.L. Clinical Manifestations, Diagnosis, and Treatment of Sarcoidosis. Mayo Clin. Proc. Innov. Qual. Outcomes. 2019. Т. 3. № 3. С. 358–375.
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Bibliography link
Yessengeldinova M.A., Bakenova R.A., Seisembekov T.Z. A clinical case of pulmonary sarcoidosis in a patient with cancer // Nauka i Zdravookhranenie [Science & Healthcare]. 2021, (Vol.23) 2, pp. 162-169. doi 10.34689/SH.2021.23.2.018Related publications:
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