MORBIDITY AND MORTALITY RATE OF BREAST CANCER IN KAZAKHSTAN, 2015-2019
Introduction. Female breast cancer has now surpassed lung cancer as the leading cause of global cancer incidence in 2020, with an estimated 2.3 million new cases, representing 11.7% of all cancer cases. It is the fifth leading cause of cancer mortality worldwide, with 685,000 deaths.
Aim of our study was to define the morbidity and mortality from breast cancer in the Republic of Kazakhstan for the period 2015-2019.
Materials and Methods: The analysis of the incidence and mortality of breast cancer in the in the Republic of Kazakhstan for the period 2015-2019 has been carried out. The data for the analysis were extracted from official statistical sources: Forms No. 35 Annual "Report on patients with malignant neoplasms». The incidence rates were calculated as the number of cases per 100000 person-years of follow-up. The number of population is obtained from the Bureau of National Statistics of the Agency for Strategic Planning and Reform of the Republic of Kazakhstan. A direct standardization method was used for calculation of the standardized morbidity and mortality rate [11].
Results. The incidence rate of breast cancer increased in 2016, decreased in 2017, then tended to increase and in 2019 the incidence rate was equal to 52,3 per 100 thousand women. The mortality rate of breast cancer during the study period decreased from 15,3 per 100 thousand women population in 2015 to 12,0 per 100 thousand women population in 2019. «Crude» rates of morbidity were high in the 65-74 year-old age group, in the second place 55-64 year-old age group, in the third place 75-84 year-old age group. Standardized incidence rates were high in the 55-64-year-old age group, followed by the 45-54-year-old age group and the 65-74-year-old age group. «Crude» mortality rates of breast cancer were high in the 65-74 year-old age group, in second place was the 75-84 year-old age group, in third place was the age group over 85 years. Standardized mortality rates were highest in the 55-64-year-old age group. In second place was the age group of 45-54 years, in third place the age group of 65-74 years.
Conclusion. The incidence of breast cancer tends to increase. The mortality rates from breast cancer during the study period tended to decrease. The «crude» incidence rates were highest in the 65-74-year-old age group. After standardization, the highest incidence rates were in the age group of 55-64 years. The «crude» mortality rates of breast cancer were high in the 65-74-year-old age group. After standardization, high mortality rates were found in the 55-64-year-old age group.
Inna L. Chertischeva1, Vera Ye. Li2, Aiym B. Bekezhan4,
Adylzhan S. Masadykov3, http://orcid.org/0000-0003-3319-4908
Gulnar M. Shalgumbayeva 4, http://orcid.org/0000-0003-3310-4490
Dastan N. Sajdualiev4, http://orcid.org/0000-0002-8920-3730
1 East Kazakhstan region multi-profile “Center of Oncology and surgery”,
Ust Kamenogorsk city, Republic of Kazakhstan;
2 University Hospital NСJSC «Semey Medical University»,Semey, Republic of Kazakhstan;
3 RPA «National Center for Independent Examination», Ust Kamenogorsk city, Republic of Kazakhstan;
4 NCJSC Semey medical university, Semey city, Republic of Kazakhstan.
1. Абитова А.Ж., Бекмухамбетов Е.Ж., Назарбаева Р.К., Баспақова А.М., Аймагамбетова М.А., Жексенова А.Н. Ақтөбе облысы бойынша сүт безі қатерлі ісігінің эпидемиологиясы // Батыс Қазақстан медицина журналы. 2018. 59(3). С. 84–88
2. Антоненкова Н.Н., Курьян Л.М., Якимович Г.В., Скалыженко А.П. Эпидемиологические особенности рака молочной железы у женщин репродуктивного возраста и пути совершенствования диагностики фоновых и предраковых заболеваний гениталий у пациенток, перенесших специальное лечение // Онкологический журнал, 2010. 4.4(16). С.18–238.
3. Балмаганбетова Ф.К., Нургалиева Р.Е., Тухватшин Р.Р., Жексенова А.Н., Калдыбаева А.Т., Аманжолқызы А., Булекова З.С. Современные аспекты эпидемиологии рака молочной железы: обзор литературы // West Kazakhstan Medical Journal. 2020. №62(2). P.125–133
4. Безнощенко Г.Б., Кравченко Е.Н., Кропмаер К.П., Макаркина Л.Г., Гуртавлева К.С. Современные патогенетические аспекты доброкачественных дисплазий молочных желез // Мать и дитя в Кузбассе. 2018. №72. С.93–96.
5. Бейсебаев Е.Н. Оценка роли социальных детерминантов в скрининговых исследованиях и 5-летней выживаемости женщин с заболеванием рака молочной железы: дис. … док.философии (PhD): 6D110200. – Алматы: КазНМУ им. С.Д. Асфендиярова, 2015. – 89 с
6. Заридзе Д.Г., Максимович Д.М. Профилактика злокачественных новообразований. //V-Петербургский Международный онкологический форум. Сборник. – 2017. №4 (2). DOI.org/10.17650/2313805X-2017-4-2-8-25
7. Магзумов Ж.М., Масадыков А.С., Сиязбекова З.С., Шалгумбаева Г.М. Эпидемиология рака гортани в Казахстане в 2008–2017 годах // Наука и Здравоохранение. 2019. № 2 (Т.21). С. 91-97
8. Нурманова А., Султанова З.И., Аннаоразов Ы.А. Факторы и их роль в заболеваемости, смертности, выживаемости при раке молочной железы // Вестник КазНМУ. 2019. №1. С.112-114
9. Bray F., McCarron P., Parkin D.M. The changing global patterns of female breast cancer incidence and mortality // Breast Cancer Res. 2004. Vol.6. Р. 229-239.
10. Brinton L.A., Gaudet M.M., Gierach G.L., Thun M., Linet M.S., Cerhan J.R., Haiman C.A., Schottenfeld D. Cancer Epidemiology and Prevention. 4th ed. Oxford University Press. 2018. Р. 861-888
11. Hazel I. Standardization Methods. Wiley StatsRef: Statistics Reference Online, 2014. P.1-17 https://doi.org/10.1002/9781118445112.stat06116 (14 April 2014)
12. Joko-Fru W.Y., Jedy-Agba E., Korir A., et al. The evolving epidemic of breast cancer in sub-Saharan Africa: results from the African Cancer Registry Network // Int J Cancer. 2020. Vol. 147. p. 2131-2141.
13. Lei Fan, Paul E. Goss, Kathrin Strasser-Weippl. Current Status and Future Projections of Breast Cancer in Asia // Breast Care. 2015. Vol. 10. - P.372–378 DOI: 10.1159/000441818
14. Sung H., Ferlay J., Siege R.L., Laversanne M., Soerjomataram I., Jemal A., Bray F., Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries // CA CANCER J CLIN 2021. Vol. 1 (41). p.11
15. Youn H.J., Han W. A Review of the Epidemiology of Breast Cancer in Asia: Focus on Risk Factors // Asian Pac J Cancer Prev, 2020. 21 (4), 867-880 DOI:10.31557/APJCP.2020.21.4.867
References:
1. Abitova A.Zh., Bekmuhambetov E.Zh., Nazarbaeva R.K., Baspaқova A.M., Ajmagambetova M.A., Zheksenova A.N.. Aktobe oblysy boiynsha sүt bezі katerlі іsіgіnіn epidemiologiyasy [Epidemiology of breast cancer in Aktobe region]. Batys Kazakstan meditsina zhurnaly [West Kazakhstan medical journal]2018. 59(3):4–88 [in Kazak]
2. Antonenkova N.N., Kur'jan L.M., Jakimovich G.V., Skalyzhenko A.P. Jepidemiologicheskie osobennosti raka molochnoj zhelezy u zhenshhin reproduktivnogo vozrasta i puti sovershenstvovanija diagnostiki fonovyh i predrakovyh zabolevanij genitalij u pacientok, perenesshih special'noe lechenie [Epidemiological features of breast cancer at women of reproductive age and ways to improving of diagnosis of backround of precancerous diseases of the genitals in patients who have undergone for special treatment]. Onkologicheskii zhurnal [Oncology journal]. 2010;4.4(16):18–238 [in Russian]
3. Balmaganbetova FK, Nurgalieva RE, Tuhvatshin RR, Zheksenova AN, Kaldybaeva AT, Amanzholқyzy A, Bulekova ZS. Sovremennye aspekty jepidemiologii raka molochnoj zhelezy: obzor literatury [Modern aspects of the epidemiology of breast cancer: literature revieu]. West Kazakhstan Medical Journal [West Kazakhstan medical journal]. 2020. №;62(2). P.125–133 [in Russian]
4. Beznoshhenko G.B., Kravchenko E.N., Kropmaer K.P., Makarkina L.G., Gurtavleva K.S. Sovremennye patogeneticheskie aspekty dobrokachestvennyh displazij molochnyh zhelez [Modern pathogenetic aspects of benign dysplasia of mammary glands]. Mat' i ditja v Kuzbasse [Mother and child of Kuzbasse]. 2018. №72. pp.93–96[in Russian]
5. Bejsebaev E.N. Ocenka roli social'nyh determinantov v skriningovyh issledovanijah i 5-letnej vyzhivaemosti zhenshhin s zabolevaniem raka molochnoj zhelezy: dis. … dok.filosofii (PhD): 6D110200 [Evaluation of the role of social determinants in screening studies and 5-years survival of women with breast cancer]. – Almaty: KazNMU im. S.D. Asfendijarova, 2015. – 89 p [in Russian]
6. Zaridze D.G., Maksimovich D.M. Profilaktika zlokachestvennyh novoobrazovanij [Prevention of cancer]. V-Peterburgskii Mezhdunarodnyi onkologicheskii forum. Sbornik [V – Petersburg International Cancer Forum]. 2017. №4 (2). DOI.org/10.17650/2313805X-2017-4-2-8-25 [in Russian]
7. Magzumov Zh.M., Masadykov A.S., Sijazbekova Z.S., Shalgumbaeva G.M. Jepidemiologija raka gortani v Kazahstane v 2008–2017 godah [Epidemiology of laryngeal cancer in Kazakhstan for 2008-2017]. Nauka i Zdravookhranenie [Scince & healthcare]. 2019. № 2 (T.21). - pp. 91-97 [in Russian]
8. Nurmanova A., Sultanova Z.I., Annaorazov Y.A. Faktory i ih rol' v zabolevaemosti, smertnosti, vyzhivaemosti pri rake molochnoj zhelezy [Factors and their role in mormility, mortality and survival in breast cancer]. Vestnik KazNMU [Bulletin of KazNMU]. 2019. №1. pp.112-114[in Russian]
9. Bray F., McCarron P., Parkin D.M. The changing global patterns of female breast cancer incidence and mortality. Breast Cancer Res. 2004. Vol.6. Р. 229-239.
10. Brinton L.A., Gaudet M.M., Gierach G.L., Thun M., Linet M.S., Cerhan J.R., Haiman C.A., Schottenfeld D. Cancer Epidemiology and Prevention. 4th ed. Oxford University Press. 2018. Р. 861-888
11. Hazel I. Standardization Methods. Wiley StatsRef: Statistics Reference Online, 2014. P.1-17 https://doi.org/10.1002/9781118445112.stat06116 (14 April 2014)
12. Joko-Fru W.Y., Jedy-Agba E., Korir A., et al. The evolving epidemic of breast cancer in sub-Saharan Africa: results from the African Cancer Registry Network. Int J Cancer. 2020. Vol. 147. p. 2131-2141.
13. Lei Fan, Paul E. Goss, Kathrin Strasser-Weippl. Current Status and Future Projections of Breast Cancer in Asia. Breast Care. 2015. Vol. 10. - P.372–378 DOI: 10.1159/000441818
14. Sung H., Ferlay J., Siege R.L., Laversanne M., Soerjomataram I., Jemal A., Bray F., Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA CANCER J CLIN 2021. Vol. 1 (41). p.11
15. Youn H.J., Han W. A Review of the Epidemiology of Breast Cancer in Asia: Focus on Risk Factors. Asian Pac J Cancer Prev, 2020. 21 (4), 867-880 DOI:10.31557/APJCP.2020.21.4.867
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Bibliography link
Chertischeva I.L., Li V.Ye., Bekezhan A.B., Masadykov A.S., Shalgumbayeva G.M., Sajdualiev D.N. Morbidity and mortality rate of breast cancer in Kazakhstan, 2015-2019 // Nauka i Zdravookhranenie [Science & Healthcare]. 2021, (Vol.23) 2, pp. 148-154. doi 10.34689/SH.2021.23.2.016Related publications:
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