MEDICAL-STATISTICAL ANALYSIS OF ACUTE CEREBROVASCULAR DISEASES: STUDY IN KARAGANDA REGION, REPUBLIC OF KAZAKHSTAN
Relevance: at the moment, there is relatively little data on the clinical and epidemiological features of the course of acute cerebrovascular diseases in Kazakhstan, especially in the Karaganda region. Aim: to identify the features of the morbidity and mortality rates among patients who underwent certain types of acute cerebrovascular diseases. Materials and methods: We conducted a descriptive epidemiological study to assess acute brain catastrophes in the Karaganda region, Kazakhstan. The data is taken from the register of diseases in the Karaganda region, for patients hospitalized from January 1, 2019 to December 31, 2019 with diagnoses corresponding to the ICD codes I60-I64. Statistical analysis of the data was conducted using the trial version of the STATISTICA 13.3 EN program. Following descriptive statistics were performed: absolute number (n), relative number (%), 95% confidence interval (Wilson's method), standard deviation (SD), mean value (ME), upper and lower quartiles (Q25-Q75). After checking the data for normal distribution, nonparametric tests were used: comparison of two independent groups - Mann-Whitney U-test, and also three or more independent groups - Kruskal-Wallis H-test. Significance level p <0.05. Morbidity and mortality rates were calculated using standard formulas per 100,000 population. Results: The total number of hospitalizations per 100,000 population with hemorrhagic stroke is 47.8, with ischemic stroke is 203.5. With subarachnoid hemorrhage, the highest frequency of hospitalizations in the age group of 51-60 years, with intracerebral hemorrhage - 61-70 years, with ischemic stroke - in people over 70 years. The hospital and 30-day mortality rate after discharge from the hospital for all types of stroke was 49.9 cases per 100,000 population. 32.9% of patients with subarachnoid hemorrhage, 30.07% with intracerebral hemorrhage, and 12.7% of patients with ischemic stroke died in the hospital. Conclusions: The distribution of stroke subtypes and mortality in the Karaganda region corresponds to global trends. There were no significant differences in the incidence of stroke subtypes by gender. There were no age differences between men and women when hospitalized with ICD I60, I62, I64 diagnoses (p > 0.05), but there were differences in ICD I61, I63 diagnoses, as well as between all cases of stroke (p < 0.05). But the indicators of hospital mortality from acute cerebrovascular diseases in the Karaganda region are 3.2 times higher than the data for Kazakhstan. The death rate from stroke at home within 1 month after discharge in our region is 1.4 times higher than in the republic. Revealed gender differences in the level of mortality, with a predominance in women. The results of the study can be used in the strategy of prevention and treatment of acute cerebrovascular diseases in Kazakhstan.
Nurtas I. Tursynov ¹, https://orcid.org/0000-0003-1939-7506 Shynar S. Muratbekova ¹, https://orcid.org/0000-0002-4657-4021 Marina A. Grigolashvili ¹, https://orcid.org/0000-0001-6722-1762 ¹ NJSC "Medical University of Karaganda", Karaganda, Republic of Kazakhstan
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Турсынов Н.И., Муратбекова Ш.С., Григолашвили М.А. Медико-статистический анализ острых цереброваскулярных заболеваний: исследование по Карагандинской области, Республика Казахстан // Наука и Здравоохранение. 2021. 4(Т.23). С. 147-154. doi 10.34689/SH.2021.23.4.016

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