THE MODERN ASPECTS OF SURGICAL TREATMENT OF DIFFUSE TOXIC GOITER. REVIEW.
Introduction. Diffuse toxic goiter (DTG) is one of the most common diseases of the endocrine system. The frequency of new cases of DTG ranges from 30 (0.03%) to 200 (0.2%) per 100 thousand population per year. is not a rare disease, despite the half-century history of studying this nosology, some questions regarding the epidemiology, clinic, diagnosis and treatment tactics remain unanswered.
Aim. To conduct a literature review on the optimization of epidemiology, clinic, diagnosis and tactics of surgical treatment of diffuse toxic goiter.
Search strategy. In the course of studying this pathology, a search was carried out for the current literature of the PubMed database (MEDLINE) and the scientific electronic library «CyberLeninka» (CYBERLENINKA) and eLIBRARY.RU with a search depth of 10 years (2011–2021). In some cases, there are links to earlier publications of historical value. The literature search included publications in Russian and English. A total of 411 sources were found, of which 52 were selected that meet the inclusion criteria and exclude newspaper publications, case reports, abstracts, and duplication or repetition of information.
Results. In recent years, there has been an increase in the number of patients with thyroid pathology (thyroid gland), and in particular, diffuse toxic goiter (DTZ). In economically developed countries, according to statistics, almost 1-2% of the population suffer from DTP. The disease can occur at any age, but the peak incidence is mainly in the working age 20-40 years. As the materials of the literature review show, despite the measures taken in the world to prevent toxic malnutrition in endemic regions for iodine deficiency and thyroid diseases, the frequency of these pathologies of the body remains above average. Therefore, due to the fact that ways to improve the results of surgical treatment of diffuse-toxic goiter are of certain scientific and practical interest, a review of the literature reflecting modern aspects of surgical treatment of diffuse-toxic goiter has been conducted. For a long time, surgical treatment has been limited, and now in many foreign countries, the method of treatment with radioiode is becoming more common. Patients with this pathology do not have a clear combined comprehensive approach to treatment.
Yerasyl A. Mukash1, https://orcid.org/0000-0002-3337-7643
Meyrbek Zh. Aimagambetov1, https://orcid.org/0000-0003-4699-8200
Altai A. Dyussupov 2, https://orcid.org/ 0000-0003-0875-1020
Nazarbek B. Omarov1, http://orcid.org/0000-0002-6201-8263
Tolkyn А. Bulegenov1 , http://orcid.org/0000-0001-6145-9649
Medet A. Auyenov1, https://orcid.org/0000-0002-1809-9091
Samatbek T. Abdrakhmanov1, https://orcid.org/0000-0002-4270-3498
Andrey N. Zharikov 3, https://orcid.org/0000-0003-4292-4781
Rinat K. Taiburov4, https://orcid.org/0000-0002-1404-0949
1 Department of Hospital and Pediatric Surgery, NСJSC «Semey Medical University»,
Semey, Republic of Kazakhstan;
2 Chairman of the Board – Rector, NСJSC «Semey Medical University», Semey, Republic of Kazakhstan;
3 Altai State Medical University of the Ministry of Health of Russia, Barnaul, Russia;
4 University Hospital NСJSC «Semey Medical University», Semey, Republic of Kazakhstan.
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Mukash Ye.A., Aimagambetov M.Zh., Dyussupov A.A., Omarov N.B., Bulegenov T.A., Auyenov M.A., Abdrakhmanov S.T., Zharikov A.N., Taiburov R.K. The modern aspects of surgical treatment of diffuse toxic goiter. Review // Nauka i Zdravookhranenie [Science & Healthcare]. 2022, (Vol.24) 3, pp. 182-193. doi 10.34689/SH.2022.24.3.021Related publications:
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