MORTALITY FROM CARDIOVASCULAR DISEASES IN THE POPULATION OF KAZAKHSTAN EXPOSED TO RADIATION
This paper reports an analysis of theSemipalatinsk historical cohort exposed to radioactive fallout from nuclear testing inthe vicinity of the Semipalatinsk nuclear test site, Kazakhstan. The cohort study, which includes 19,545 persons of exposed and comparison villages in theSemipalatinsk region, had been set up in the 1960s and comprises 582,656 personyearsof follow-up between 1960 and 1999. Radiation dose estimates in thiscohort range from 0 to 630 mGy (whole body external). Overall, the exposedpopulation showed a high mortality from cardiovascular disease. A dose-response relationship that was foundwhen analyzing the entire cohort could completely be explained by differencesbetween the baseline rates in exposed and unexposed groups. When taking thisdifference into account no statistically significant dose-response relationship for allcardiovascular disease was found.
B. Grosche1, D. Lackland2, C. Land3, S. Simon4, K. Apsalikov5, L. Pivina6
1 Federal Office for Radiation Protection, Germany;
2 Medical University of South Carolina, USA;
3 National Institutes of Health, USA;
5 Scientific Research Institute for Radiation Medicine and Ecology, Kazakhstan;
6 Semey State Medical University, Kazakhstan
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