THE ROLE OF GENE AND STRUCTURAL MUTATIONS IN THE PROGRESS OF RADIATION-INDUCED MUTAGENESIS
As realized by mechanisms of carcinogenesis was achieved sufficient progress and compiled huge material that is re-flected in selected articles. On a par proto-oncogenes are low-level, their protein products in healthy cellules are participate in regulation of apoptosis processes, proliferation, cell cooperation, regulation of signaling inside the cellule. Radiation ef-fects causing the mutations one of gene allele is factor into neoplastic cellule transformation that cause chromosomal rear-rangements and proto-oncogenes amplification. Such mutations studying is represents solitary interest for radiation biology and medicine and enlarging our knowledge in the field of mutagenesis.
M. Madiyeva, D. Balgobekova, A. Abylgazinova
Semey State Medical University
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