RISK ASSESSMENT OF SOMATIC DISEASES IN THE COHORT OF URANIUM INDUSTRY WORKERS EXPOSED TO RADIATION IN SMALL DOSES. MESSAGE II
Purpose of the article are studying the risk of chronic somatic diseases among uranium industry workers exposed to occupational radiation exposure, depending on the length of work and total accumulated radiation dose.
Material and methods: Results of cohort retrospective study among persons exposed to long-term influence of negative man-made factors on frequency and risk of somatic diseases in uranium industry workers are presented. The study covers 356 people of the group A staff of the Stepnogorsk Mining and Chemical Combine (SMCC) and 507 workers who make up the monitoring group.
The study of results statistical analysis was carried out using IBM SPSS Statistics 20 and Microsoft Excel. The following criteria and methods of statistical study were used to analyze the study data: Pearson's chi-squared test and correlation analysis.
Results: The results revealed a high prevalence of chronic diseases of workers of the main group, as well as a relationship with the total accumulated dose and experience with sources of ionizing radiation. Excessive relative risks have been identified for diseases of the endocrine and nervous system, eye, ear, circulation, digestion and skin. Cardiovascular pathology represented by essential arterial hypertension and coronary heart disease, was the most characteristic of the uranium industry.
Conclusion: In the studied cohort of workers, the prevalence of diseases depended on the length of work in the enterprise and the dose of radiation for diseases of the circulatory system, digestion, eye and nervous system. Diseases of the circulatory system, nervous, endocrine system, ear, skin can be classified as professionally conditioned.
Polat K. Kazymbet 1, https://orcid.org/0000-0003-3091-1721
Polat K. Kazymbet 1, https://orcid.org/0000-0003-3091-1721
Dujcebai D. Dzhanabayev 1, https://orcid.org/000-0001-8051-6637
Elena A. Saifulina2, https://orcid.org/0000-0002-1791-0137
Yerlan T. Kashkinbayev 1, https://orcid.org/0000-0002-6095-459Х
Danara S. Ibrayeva 1, https://orcid.org/0000-0002-1640-1728
Sholpan K. Khussain 1, https://orcid.org/000-0001-7640-5686
1 Institute of Radiobiology and Radiation Protection nCJSC «Medical University of Astana»,
Nur-Sultan city, Republic of Kazakhstan;
2 Department of Pathological Physiology named after V.G. Korpacheva nCJSC «Medical University of Astana», Nur-Sultan city, Republic of Kazakhstan.
1. Бекенова Ф.К. Радиационные эффекты у рабочих ураноперерабатывающей промышленности: риски хронических заболеваний внутренних органов, особенности окислительного метаболизма, цитогенети-ческая нестабильность… дисс…док.мед.наук. Астана. 2010. 112с.
2. Ильичева В.Н. Сравнительная гистохимическая характеристика различных зон коры головного мозга крыс после облучения // Российский медико-биологический вестник имени академика И.П. Павлова - 2011. №4. С.8.
3. Казымбет П.К., Бахтин М.М., Кашкинбаев Е.Т., Джанабаев Д., Даутбаева Ж.C., Шарипов М.К. Радиационная обстановка на хвостохранилище Степногорского горно-химического комбината и прилегающих территориях. Сообщение I. // Медицинская радиология и радиационная безопасность. 2018. Том 63. № 1. С. 40–47
4. Казымбет П. Радиация и риск: соматические заболевания персонала уранодобывающих предприятий Том II. Под общей редакцией проф. П. Казымбет. Астана. 2015. 183 с.
5. Карпов А.Б., Семенова Ю.В., Литвиенко Т.М. и др. Сердечно-сосудистая система и ионизирующее излучение. Часть I / Острый инфаркт миокарда. // Под общ.ред. Р.М. Тахауова изд.Томского Университета. 2009. С.175-176
6. Куцевляк В.Ф., Лахтин Ю.В. Этиологическая доля влияния солей тяжелых металлов на относительный риск возникновения заболеваний пародонта // Вестник стоматологии 2010. № 3, С.32-34.
7. Моисеева М.Б. Показатели заболеваемости и смертности от цереброваскулярных заболеваний в когорте работников, подвергшихся профессиональному облучению // Медицинская радиология и радиационная безопасносность. 2018, Т.63. № 3. С.5-11.
8. Окладникова Н.Д. Клинические аспекты действия урана на организм человека // Вопросы радиационной безопасности ЮУрИБФ. 2003. С.26-32.
9. Bouet S., Samson E., Jovanovic I., Laurier D., Laurent O. First mortality analysis in the French cohort of uranium millers (F-Millers), period 1968-2013 // Int Arch Occup Environ Health. 2018 Jan;91(1): p.23-33.
10. Figgs L.W. Lung cancer mortality among uranium gaseous diffusion plant workers: a cohort study 1952-2004 // Int J Occup Environ Med. 2013 Jul;4(3): p.128-40.
11. Grellier J., Atkinson W., Bérard P. Risk of lung cancer mortality in nuclear workers from internal exposure to alpha particle-emitting // Radionuclides. Epidemiology. 2017 Sep;28(5): pр.675-684.
12. Kazymbet P.K., Seisebaev A.T. Problems of the complex assessment of radiobioеcological situation and public health in uranium-extraction region of Kazakhstan // Радиационная биология. Радиоэкология. 2002. Т. 42. №6. С. 750–753
13. Kreuzer M., Sobotzki C., Fenske N. Leukaemia mortality and low-dose ionising radiation in the WISMUT uranium miner cohort (1946-2013) // Occup Environ Med. 2017 Mar;74(4):252-258
14. Yiin J.H., Anderson J.L., Daniels R.D. Mortality in a combined cohort of uranium enrichment workers. Am J Ind Med. 2017 Jan;60(1):96-108.
References:
1. Bekenova F.K. Radiatsionnye effekty u rabochikh uranopererabatyvayushchei promyshlennosti: riski khronicheskikh zabolevanii vnutrennikh organov, osobennosti okislitel'nogo metabolizma, tsitogeneticheskaya nestabil'nost': (avtoref. dokt. diss.) [Radiation effects in workers of uranium processing industry: risks of chronic diseases of internal organs, peculiarities of oxidative metabolism, cytogenetic instability. Author’s Abstract of Doct. Diss.]. Astana, 2010. 112р. [in Russian]
2. Il'icheva V.N. Sravnitel'naya gistokhimicheskaya kharakteristika razlichnykh zon kory golovnogo mozga krys posle oblucheniya [Comparative histochemical characterization of different areas of rat cerebral cortex after irradiation]. Rossiiskii mediko-biologicheskii vestnik imeni akademika I.P. Pavlova [Russian medical and biological bulletin named after academician I.P. Pavlov] - 2011. - №4. - pp.8. [in Russian]
3. Kazymbet P.K., Bahtin M.M., Kashkinbaev E.T., Dzhanabaev D., Dautbaeva Zh.C., Sharipov M.K. Radiacionnaja obstanovka na hvostohranilishhe Stepnogorskogo gorno-khimicheskogo kombinata i prilegayushhikh territoriyakh. Soobshhenie I. [Radiation situation on the tailings dam of Stepnogorsk Mining and Chemical Plant and adjacent territories. Message I]. Meditsinskaya radiologiya i radiatsionnaya bezopasnost' [Medical radiology and radiation safety]. 2018. Tom 63. № 1. pp. 40–47 [in Russian]
4. Kazymbet P. Radiatsiya i risk: somaticheskie zabolevaniya personala uranodobyvayushchikh predpriyatii Tom II [Radiation and risk: somatic diseases of uranium mining personnel Vol. II]. Pod obshchei redaktsiei prof. P. Kazymbet. Astana 2015. 183 c. [in Russian]
5. Karpov A.B., Semenova Yu.V., Litvienko T.M. i dr. Serdechno-sosudistaya sistema i ioniziruyushchee izluchenie. Chast' I [Cardiovascular system and ionizing radiation. Part I] Ostryi infarkt miokarda. Pod obshch.red. R.M. Takhauova izd. Tomskogo Universiteta]. 2009. p.175-176 [in Russian]
6. Kutsevlyak V.F., Lakhtin Yu.V. Etiologicheskaya dolya vliyaniya solei tyazhelykh metallov na otnositel'nyi risk vozniknoveniya zabolevanii parodonta [Etiological share of the effect of heavy metal salts on the relative risk of periodontal diseases] Vestnik stomatologii [Bulletin of stomatology] 2010, № 3, pp.32-34. [in Russian]
7. Moiseeva M.B. Pokazateli zabolevaemosti i smertnosti ot tserebrovaskulyarnykh zabolevanii v kogorte rabotnikov, podvergshikhsya professional'nomu oblucheniyu [Incidence and mortality rates from cerebrovascular diseases in the cohort of workers exposed to occupational radiation] Meditsinskaya radiologiya i radiatsionnaja bezopasnosnost' [Medical radiology and radiation safety]. 2018, V.63. № 3.pp.5-11. [in Russian]
8. Okladnikova N.D. Klinicheskie aspekty deistviya urana na organizm cheloveka [Clinical aspects of the effect of uranium on the human body]. Voprosy radiatsionnoi bezopasnosti JuUrIBF [Issues of radiation safety of SUrInstBioph] 2003. pp.26-32. [in Russian]
9. Bouet S., Samson E., Jovanovic I., Laurier D., Laurent O. First mortality analysis in the French cohort of uranium millers (F-Millers), period 1968-2013. Int Arch Occup Environ Health. 2018 Jan;91(1): p.23-33.
10. Figgs L.W. Lung cancer mortality among uranium gaseous diffusion plant workers: a cohort study 1952-2004. Int J Occup Environ Med. 2013 Jul;4(3): pp.128-40.
11. Grellier J., Atkinson W., Bérard P. Risk of lung cancer mortality in nuclear workers from internal exposure to alpha particle-emitting. Radionuclides. Epidemiology. 2017 Sep;28(5): pp.675-684.
12. Kazymbet P.K., Seisebaev A.T. Problems of the complex assessment of radiobioеcological situation and public health in uranium-extraction region of Kazakhstan. Radiation biology. Radioecology. 2002. Т.42. №6. pp. 750–753.
13. Kreuzer M., Sobotzki C., Fenske N. Leukaemia mortality and low-dose ionising radiation in the WISMUT uranium miner cohort (1946-2013). Occup Environ Med. 2017. Mar;74(4):252-258.
14. Yiin J.H., Anderson J.L., Daniels R.D. Mortality in a combined cohort of uranium enrichment workers. Am J Ind Med. 2017 Jan;60(1):96-108
Количество просмотров: 648
Категория статей:
Оригинальные исследования
Библиографическая ссылка
Казымбет П.К., Джанабаев Д.Д., Сайфулина Е.A., Кашкинбаев Е.T., Ибраева Д.С., Хусаин Ш.К. Оценка риска соматических заболеваний в когорте работников урановой промышленности, подвергающихся радиационному воздействию в малых дозах. Сообщение II // Наука и Здравоохранение. 2019. 5 (Т.21). С. 81-87.
Похожие публикации:
МЕХАНИКАЛЫҚ САРҒАЮ ОПЕРАЦИЯСЫ КЕЗІНДЕ КОАГУЛОПАТИЯЛЫҚ ҚАН КЕТУДІҢ АЛДЫН АЛУ ӘДІСІ
ОПТИМИЗАЦИЯ РЕЗУЛЬТАТОВ АУТОДЕРМОПЛАСТИКИ ПРИ ЛЕЧЕНИИ ГРАНУЛИРУЮЩИХ ГНОЙНЫХ РАН
BASICS OF REHABILITATION OF CHILDREN AFTER OPERATIONS ON THE COLON AND ANORECTAL AREA
HEALTH INDICATORS OF FIRST-YEAR-OF-LIFE CHILDREN IN THE REPUBLIC OF KAZAKHSTAN FOR 2013-2022
ОЦЕНКА УДОВЛЕТВОРЕННОСТИ ТРУДОВОЙ ДЕЯТЕЛЬНОСТЬЮ ВРАЧЕЙ АНЕСТЕЗИОЛОГОВ-РЕАНИМАТОЛОГОВ ГОРОДА АСТАНА