MICROSCOPIC PECULIARITIES OF DIFFERENT FORM OF GASTROESOPHAGEAL REFLUX DISEASE
DOI:
https://doi.org/10.34689/1n909j70Keywords:
esophagus , reflux , histology , metaplasiaAbstract
The work devoted for investigation of the prevalence and significance of microscopic changes in the esophageal mucosa
in gastroesophageal reflux disease (GERD) for the biopsy results. It was studied 223 patients with biopsy, which have been
diagnosed with GERD. Material was divided after comparing endoscopic and histological data into three subgroups: nonerosive GERD was referred 104 cases or 46.64%; the picture of erosive ulcerous form corresponded in 77 patients, or
34.53%; Barrett's esophagus was detected in 42 patients (18.8%). The following histological features were evaluated: degree
of hyperplasia of basal cells, epithelial papillae elongation, the level of infiltration with leukocyte lymphocytic elements, the
presence of erosive or ulcerative changes, the presence of metaplasia and dysplasia. Study of esophageal biopsies indicates cases of metaplasia (Barrett's esophagus) and esophageal dysplasia in GERD. All patients with GERD, a comprehensive diagnostic approach that combines not only endoscopic examination, but histological analysis of biopsy samples. Diagnostically most significant are the basal layer hyperplasia, infiltration of inflammatory cells for all forms of metaplasia and
dysplasia detection for Barrett's esophagus.
References
Гаргин В.В., Сакал В.В. Харьковский национальный медицинский университет, Украина, Институт терапии имени Л.Т. Малай НАМН Украины // Наука и Здравоохранение. 2014.№ 2. С.38-40 Gargin V.V., Sakal V.V. MICROSCOPIC PECULIARITIES OF DIFFERENT FORM OF GASTROESOPHAGEAL REFLUX DISEASE // Nauka i Zdravookhranenie. 2014.№ 2. С. 38-40 Гаргин В.В., Сакал В.В. Харьков ұлттық медициналық университеті, Украина, Л.Т. Малай атынд. терапия институты, Украина ҰМҒА // Ғылым және Денсаулық сақтау 2014.№ 2. С. 38-40 В.В., Сакал В.В. Харьковский национальный медицинский университет, Украина, Институт терапии имени Л.Т. Малай НАМН Украины // Наука и Здравоохранение. 2014.№ 2. С.38-40 Gargin V.V., Sakal V.V. MICROSCOPIC PECULIARITIES OF DIFFERENT FORM OF GASTROESOPHAGEAL REFLUX DISEASE // Nauka i Zdravookhranenie. 2014.№ 2. С. 38-40 Гаргин В.В., Сакал В.В. Харьков ұлттық медициналық университеті, Украина, Л.Т. Малай атынд. терапия институты, Украина ҰМҒА // Ғылым және Денсаулық сақтау 2014.№ 2. С. 38-40
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Copyright (c) 2026 В.В. Гаргин, В.В. Сакал (Автор)
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