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EVALUATION OF ORAL LOCAL IMMUNITY IN PATIENTS WITH MANDIBULARFRACTURES WITHOUT ANTIBIOTICS IN THE MEDICATION

Authors

  • G.P. Ruzin Автор
  • A.I. Chyryk Автор
  • S.V. Kalinichenko Автор

DOI:

https://doi.org/10.34689/dpp40v45

Keywords:

mandibular fractures , immunity , immunoglobulins , lysozyme

Abstract

It was studied the levels of secretory immunoglobulin A and lysozyme in saliva of patients with mandibular fractures, depending on the availability of antimicrobials in the scheme of medical treatment. It was determined the inverse relationship
between the day of hospitalisation and local immunity in saliva. After treatment, it was determined that, the level of sIgA in
saliva of the patients treated with antibiotics was 1.4 times lower compared with patients treated with no antibiotics, and 2.1
times lower compared with those of healthy controls. The level of lysozyme was 1.6 times lower and 2.07 times lower respectively. This study opens the question of the desirability of mandatory antibiotic prophylaxis in patients with mandibular
fractures without any disturbances of their compensatory reactions.

Author Biographies

  • G.P. Ruzin

    Харьковский национальный медицинский университет, Украина

  • A.I. Chyryk

    Харьковский национальный медицинский университет, Украина

  • S.V. Kalinichenko

    Государственное учреждение «Институт микробиологии и иммунологии им. И.И. Мечникова
    Национальной академии медицинских наук Украины», Украина

References

ХАРАКТЕРИСТИКА ИММУНОЛОГИЧЕСКИХ ПОКАЗАТЕЛЕЙ СЛЮНЫ ПРИ ЛЕЧЕНИИ БОЛЬНЫХ С ПЕРЕЛОМАМИ НИЖНЕЙ ЧЕЛЮСТИ БЕЗ ПРИМЕНЕНИЯ АНТИБИОТИКОВ

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Published

2026-02-17

Issue

Section

Статьи

How to Cite

EVALUATION OF ORAL LOCAL IMMUNITY IN PATIENTS WITH MANDIBULARFRACTURES WITHOUT ANTIBIOTICS IN THE MEDICATION. (2026). Рецензируемый медицинский научно-практический журнал «Наука и здравоохранение», 15(6), 51-54. https://doi.org/10.34689/dpp40v45

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