PARANEOPLASTIC BULLOUS DERMATOSES

Abstract

The author analyzes the clinical data and paraclinical characteristics of patients with paraneoplastic bullous dermatoses.
Clinical features of Duhring`s paraneodermatoses were detected, consisting in dissemination of the process with involvement
of facial skin and with essential itching. Paraclinical characteristics are as follows: neither eosinophils, nor acantholyc cells
are detectable in the vesicular contents, Jadasson`s test is negative, histomorphologic examination shows intraepidermal
localization of the vesicle. In paraneopemphigus involvement of the mucosae alone was recorded, and the painful syndrome
whose severity did not correlate with the depth of the pathologic foci; corticosteroid therapy has proved ineffective. The author recommends thorough examinations of patients with bullous dermatoses if they present with the aforesaid clinical and
paraclinical characteristics.