THE ROLE OF GENE AND STRUCTURAL MUTATIONS IN THE PROGRESS OF RADIATION-INDUCED MUTAGENESIS

Abstract

As realized by mechanisms of carcinogenesis was achieved sufficient progress and compiled huge material that is reflected in selected articles. On a par proto-oncogenes are low-level, their protein products in healthy cellules are participate
in regulation of apoptosis processes, proliferation, cell cooperation, regulation of signaling inside the cellule. Radiation effects
causing the mutations one of gene allele is factor into neoplastic cellule transformation that cause chromosomal rearrangements and proto-oncogenes amplification. Such mutations studying is represents solitary interest for radiation biology and
medicine and enlarging our knowledge in the field of mutagenesis.