OSTEODENSITOMETRY PARAMETERS ADOLESCENTS AGED 12-18 YEARS IN AKTOBE
Introduction. Conducted in the last decade, epidemiological studies have convincingly demonstrated that the OP problem originates in childhood in adult patients. It is known, that the formation of bones occurs in the early years of life, their mass (mineral density) reaches a maximum by 18-20 years. Violation of the processes of bone formation in a child under the influence of so-called pre-morbid conditions or chronic diseases leads to the formation of a decrease in bone strength already in childhood and, as a consequence, an increased risk of osteoporosis and bone fractures in the future. Lack of accumulation of peak bone mass is a major risk factor for OP, as formed by the consideration of age bone substance consumed afterwards. In this regard, the study of the features of the formation of bone mass in children is an actual direction of modern medicine.
Purpose of research: Determine the influence of sex, age, body weight and growth on the osteodensitometric parameters of the heel bone of healthy children aged 12-18 years.
Materials and Methods: The design of the study is a cross-sectional one-stage, descriptive study.In order to study the state of bone mineral density (BMD) in healthy children osteodensitometry of the heel bone was performed on the ultrasonic densitometer (SONOST-3000, South Korea). The study examined 396 adolescent students. There are given anthropometric and densitometric indicators of study participants. In the course of the study, densitometric examination of bone tissue was performed in 396 teenage schoolchildren. There are given anthropometric and densitometric indicators of the study participants. All statistical analysis was carried out using the software Statistica 10. Student's criterion was used for an independent sample of qualitative parameters and for determining statistical differences in individual sex groups. With the help of a simple linear regression analysis was determined the relationship in individual sex groups. A p value of ˂0.05 was taken as significant.
Conclusions: According to anthropometric indicators boys were differ, girls’ densitometric indicators (percentages of bone mineral density (Z-score %) and slowing broadband ultrasonic waves (BUA)) are characterized by relatively high.
BUA indicators in age dynamics from 12 to 18 years stable increased in boys, while in girls decreased. In the course of regression analysis by gender, the relationship between body mass index and BUA (R2=0,3; R2=0,26; р<0,005). In accordance with the obtained results, in the early stages of puberty, it requires further in-depth study, but the girls are confirmed with a low BMD.
Ainur Amanzholkyzy, htpp://orcid.org/0000-0002-1980-9032
Roza E. Nurgalieva, htpp://orcid.org/0000-0002-9713-8262
Zhumabek B. Dosymov, htpp://orcid.org/0000-0003-3237-2207
Farida K. Balmaganbetova, htpp://orcid.org/0000-0001-9821-6528
Maiganym Zh. Almakhanova, htpp://orcid.org/0000-0002-0794-4165
West Kazakhstan Marat Ospanov State Medical University,
Department of Normal Physiology, Aktobe, Republic of Kazakhstan
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