ASSOCIATION OF POLYMORPHISMS OF GENES OF IL1B (RS1143627), IL10 (RS1800896), IL17А (RS 2275913, RS8193036) WITH INFECTIOUS DISEASES INCLUDING ERYSIPELAS
The investigate of polymorphism of cytokine genes is an important in pathogenesis of many diseases and in identifying susceptibility to them. Knowledge of their role in the pathogenesis of many diseases, particularly infectious diseases are permits, on the one hand, to predict risk of disease or severity of its flow, on the other - to pick up individually specific therapy for a particular patient.
Despite the fact that to date, in the literature there are a significant number of studies that found an association between polymorphisms of cytokine genes and susceptibility to infectious diseases, the opinions of the authors about of markers of predisposition or resistance to infections, depending on the origin (viral or bacterial infection) are inconsistent.
The aim of this systematic review are analysis of publications on the association of polymorphisms of cytokine genes (rs1143627, rs1800896 rs8193036, rs 2275913) with infectious diseases, including erysipelas for identify the markers of susceptibility to infectious diseases.
Materials and methods. The study included full-text publications in English and Russian languages over the past 10 years, which was investigated genetic markers to infectious diseases on the basis of cytokine gene polymorphisms (rs1143627, rs8193036, rs 2275913, rs1800896).
Results. As a result, the search has been identified 786 sources in databases Pubmed, Scopus, e -Library. After the screening were selected and included in the study 18 full-text articles.
Conclusions. Polymorphism of IL10 gene (rs1800896) plays key role at chronic viral hepatitis C. Practicullar, GG genotype was associated with susceptibility to chronic viral hepatitis C. Allele T and TT genotype of polymorphism rs1143627 of IL1B gene are poor factors of susceptibility, development and current of infectious diseases, independent of genesis (viral or bacterial etiology).
Nazira B. Bekenova 1, http://orcid.org/0000-0002-3312-3299
Andrej M. Grjibovski 2-5, http://orcid.org/0000-0002-5464-0498
Lidiya A. Mukovozova 1, http://orcid.org/0000-0001-9732-3102
1 Semey State Medical University, Semey, Kazakhstan;
2 Norwegian Institute of Public Health, Oslo, Norway;
3 Northern State Medical University, Arkhangelsk, Russia;
4 International Kazakh-Turkish University, Turkestan, Kazakhstan;
5 North-Eastern Federal University, Yakutsk, Russia.
1. Бекенова Н.Б., Гржибовский А.М., Муковозова Л.А., Смаил Е. М., Токаева А.З., . Полиморфизм rs8193036 гена ИЛ-17А в казахской популяции и его связь с продукцией ИЛ-17А у больных рожей // Экология человека. 2016. №. 4. С.50-55.
2. Бекенова Н.Б., Гржибовский А.М., Муковозова Л.А., Аукенов Н.Е. Полиморфизм гена ИЛ10 в положении -1082G/A у больных рожей // Наука и здравоохранение. 2016. № 3. С. 34-45.
3. Бережная Н.М., Сепиашвили Р.И. Семейство интерлейкинов-17 // Аллергология и иммунология. 2010. №. 3. С.213-224.
4. Емельянова А.Н., Витковский Ю.А., Кижло Л.Б., Калинина Э.Н. Прогностическое значение генетического полиморфизма молекул Il-2 (Т330G), Il-10 (С819Т), Il-10 (G1082A) у больных рожей в Забайкальском крае // Дальневосточный журнал инфекцион-ной патологии. 2012. № 21. С. 159-163.
5. Емельянова А.Н., Витковский Ю.А. Генетический полиморфизм IL-10 и CRP у больных с циррозом печени вирусной этиологии // Сибирский медицинский журнал (Иркутск). 2013. Т. 119. №. 4. С.39-41.
6. Емельянова А.Н., Витковский Ю.А. Полиморфизм генов цитокинов ИЛ-2 (T330G), ИЛ10 (С819Т) и ИЛ-10 (G1082A) при хроническом вирусном гепатите С // Молекулярная медицина. 2013. №. 3. С. 46-48.
7. Ризванова Ф.Ф., Пикуза О.И., Файзуллина Р.А., Гайфуллина Р.Ф., Ризванов А.А., Кравцова О.А. Генетическая диагностика: полиморфизм генов цитокинов // Практическая медицина. 2010. №. 6. С.41-43.
8. Симбирцев А.С., Громова А.Ю. Функциональный полиморфизм генов регуляторных молекул воспаления // Цитокины и воспаление. 2005. №. 1. С.1-10.
9. Холматова К.К., Харькова О.А., Гржибовский А.М. Классификация научных исследований в здравоохранении // Экология человека. 2016. №. 1. С.57-64.
10. Холматова К. К., Горбатова М.А., Харькова О. А., Гржибовский А. М. Поперечные исследования: планирование, размер выборки, анализ данных // Экология человека. 2016. №. 2. С. 49-56.
11. Холматова К. К., Гржибовский А. М. Применение исследований «Случай-контроль» в медицине и общественном здравоохранении // Экология человека. 2016. №. 8. С.53-60.
12. Afzal M. S., Tahir S., Saiman A., Baig T.A., Shafi T., Zaidi N., Qadri I. Analysis of interleukin-10 gene polymorphisms and hepatitis C susceptibility in Pakistan // The Journal of Infection in Developing Countries. 2011. Vol.06. Р. 473-479.
13. Brooks D.G, Trifilo M., Edelmann K., Teyton L., Mc. Gavern D.B, Oldstone M.B. Interleukin-10 determines viral clearance or persistence in vivo // Nature medicine. 2006. Vol. 12(11). Р. 1301-1309.
14. da Silva N.M, Germano F.N, Vidalez –Braz B.M, Carmo Zanella Rd, dos Santos D.M, Lobato R, de Martinez A.M. Polymorphisms of IL-10 gene in patients infected with HCV under antiviral treatment in southern Brazil // Cytokine. 2015. Vol. 73(2). Р. 253-257.
15. Dong C. Regulation and pro‐inflammatory function of interleukin‐17 family cytokines // Immunological reviews. 2008. Vol.. 1. Р. 80-86.
16. Hu Y., Wu L., Li D., Zhao Q., Zhang W., Xu B. Association between cytokine gene polymorphisms and tuberculosis in a Chinese population in Shanghai: a case–control study // BMC immunology. 2015. Vol. 16(1). P. 1-10.
17. Haukim N., Bidwell J.L., Smith A.J., Keen L.J., Gallagher G., Kimberly R., Huizinga T., McDermott M.F., Oksenberg J., McNicholl J., Pociot F., Hardt C., DAlfonso S. Cytokine gene polymorphism in human disease: on-line databases, supplement 2 // Genes and immunity. 2002. Vol. 6. Р. 313-330.
18. Hayashi R., Tahara T., Shiroeda H., Saito T., Nakamura N., Tsutsumi M., Shibata T., Arisava T.. Influence of IL17A polymorphisms (rs2275913 and rs3748067) on the susceptibility to ulcerative colitis // Clinical and experimental medicine. 2013. Vol. 13(4). P. 239-244.
19. Ishida C., Ikebuchi Yu., Kinya O., Murawaki Y. Functional gene polymorphisms of interleukin-10 are associated with liver disease progression in Japanese patients with hepatitis C virus infection // Internal Medicine. 2011. Vol. 50 (7). P. 659-666.
20. Joshi L., Ponnana M., Sivangala R., Chelluri L.K., Nallari P., Penmetsa S., Valluri V., Gaddam S. Evaluation of TNF-α, IL-10 and IL-6 cytokine production and their correlation with genotype variants amongst tuberculosis patients and their household contacts // PloS one. 2015. Vol. 10(9). P.1-15.
21. Li N., Zhu Q., Li Zh., Han Q., Zhang G., Chen J., Xing F., Chen Y., Zeng X., Liu J. IL17A gene polymorphisms, serum IL‐17A and IgE levels, and hepatocellular carcinoma risk in patients with chronic hepatitis B virus infection // Molecular carcinogenesis. 2014. Vol. 6. P. 447-457.
22. Liu Y. et al. Genetic variants in IL1A and IL1B contribute to the susceptibility to 2009 pandemic H1N1 influenza A virus // BMC immunology. 2013. Vol. 1. Р. 1-10.
23. McGuire W., Hill A.V., Allsopp C.E., Greenwood B.M, Kwiatkowski D. Variation in the TNF-α promoter region associated with susceptibility to cerebral malaria // Nature. 1994. Vol. 371(6497). P. 508-511.
24. Meenakshi P., Ramya S., Shruthi T., Lavanya J., Mohammed H.H., Vijayalakshmi V., Sumanlatha G. Association of IL‐1β+ 3954 C/T and IL‐10‐1082 G/A Cytokine Gene Polymorphisms with Susceptibility to Tuberculosis // Scandinavian journal of immunology. 2013. Vol. 78(1). Р. 92-97.
25. Mira J.P, Cariou A., Grall F., Delclaux C., Losser M.R., Heshmati F., Cheval C., Monchi M., Teboul J.L., Riché F., Leleu G.,Arbibe L., Mignon A., Delpech M., Dhainaut J.F. Association of TNF2, a TNF-α promoter polymorphism, with septic shock susceptibility and mortality: a multicenter study // Jama. 1999. Vol. 282(6). Р. 561-568.
26. Mosaad Y.M. Soliman O.E., Tawhid Z. E., Sherif D.M. Interferon‐gamma+ 874 T/A and Interleukin‐10‐1082 A/G Single nucleotide Polymorphism in Egyptian Children with Tuberculosis // Scandinavian journal of immunology. 2010. Vol. 72(4). P. 358-364.
27. Nadel S., Newport M. J., Booy R., Levin M. Variation in the tumor necrosis factor-α gene promoter region may be associated with death from meningococcal disease // Journal of Infectious Diseases. 1996. Vol. 174(4). Р. 878-880.
28. Nakada T., Russell J., Boyd J., and Walley K. Association analysis of the interleukin 17A gene in Caucasian rheumatoid arthritis patients from Norway and New Zealand // Rheumatology. 2009. Vol. 48(4). P. 367-370.
29. Ocejo-Vinyals J., de Mateo E., Hoz M. The IL-17 G-152A single nucleotide polymorphism is associated with pulmonary tuberculosis in northern Spain // Cytokine. 2013. Vol.1. Р.58–61.
30. Pereira V.A. Sánchez-Arcila J.C., Teva A., Perce-da-Silva D.S., Vasconcelos M.P., Lima C.A., Aprígio C.J., Rodrigues-da-Silva R.N., Santos D.O., Banic D.M., Bonecini-Almeida M.G., Lima-Júnior J.C., Oliveira-Ferreira J. IL10A genotypic association with decreased IL-10 circulating levels in malaria infected individuals from endemic area of the Brazilian Amazon // Malaria journal. 2015. Vol. 28(14). Р. 1-12.
31. Rafiei A. et al. Polymorphism in the interleukin-17A promoter contributes to gastric cancer // World J Gastroenterol. 2013. Vol.34. Р. 5693-5699.
32. Ramos J.A., Silva R., Hoffman L., Ramos A.L., Cabello P.H., Ürményi T.P., Villella-Nogueira C.A., Lewis-Ximenez L., Rondinelli E. Association of IL-10, IL-4, and IL-28B gene polymorphisms with spontaneous clearance of hepatitis C virus in a population from Rio de Janeiro // BMC research notes. 2012. Vol. 5(1).P. 1-6.
33. Sepahi S., Pasdar A., Ahadi M., Gerayli S., Rostami S., Meshkat Z. Haplotype Analysis of Interleukin-10 Gene Promoter Polymorphisms in Chronic Hepatitis C Infection: A Case Control Study // Viral immunology. 2014. Vol. 27(8). Р. 398-403.
34. Sodsai P. Surakiatchanukul T., Kupatawintu P., Tangkitvanich P., Hirankarn N. Association of cytokine and cytokine receptor gene polymorphisms with the risk of chronic hepatitis B // Asian Pacific Journal of Allergy and Immunology. 2013. Vol. 31(4). Р. 277-285.
35. Stappers M., Thys Y., Oosting M., Plantinga T., Ioana M., Reimnitz P., Mouton J., Netea M., Joosten L.. Polymorphisms in cytokine genes IL6, TNF, IL10, IL17A and IFNG influence susceptibility to complicated skin and skin structure infections // European Journal of Clinical Microbiology & Infectious Diseases. 2014. Vol. 33(12). P 2267-2274.
36. Tarhuni A. et al. Impact of cytokine gene variants on the prediction and prognosis of hepatocellular carcinoma in patients with cirrhosis // Journal of hepatology. 2014. Vol. 2. Р. 342-350.
37. Tunçbilek S. Relationship between cytokine gene polymorphisms and chronic hepatitis B virus infection // World journal of gastroenterology: WJG. 2014. Vol. 20. Р. 6226-6235.
38. Wang J., Liu Y., Xie L., Li S., Qin X. Association of IL-17A and IL-17F gene polymorphisms with chronic hepatitis B and hepatitis B virus-related liver cirrhosis in a Chinese population: A case-control study // Clinics and research in hepatology and gastroenterology. 2016. Vol. 40 (3).P. 288-296.
39. Wang J., Liu Y., Xie L., Li S., Qin X. Interleukin-10 promoter polymorphisms in patients with hepatitis B virus infection or hepatocellular carcinomain Chinese Han ethnic population // Hepatobiliary Pancreat Dis Int. 2005. Vol. 1. Р. 60-64.
40. Wang J., Shyur S., Wang W., Liou Y., Lin C., Wu Y., Wu L. . The polymorphisms of interleukin 17A (IL17A) gene and its association with pediatric asthma in Taiwanese population // Allergy. 2009. Vol. 64(7). P. 1056-1060.
41. Yee L.J., Tang J., Herrera J., Kaslow R. A, van Leeuwen D.J. Tumor necrosis factor gene polymorphisms in patients with cirrhosis from chronic hepatitis C virus infection // Genes and immunity. 2000. Vol. 1(6). Р. 386-390.
42. Zhang G. et al. Allele-specific induction of IL-1β expression by C/EBPβ and PU. 1 contributes to increased tuberculosis susceptibility // PLoS Pathog. 2014. Vol.10. Р.1-15.
43. Zhang T.C., Pan F.M., Zhang L.Z., Gao Y.F., Zhang Z.H., Gao J., Ge R., Mei Y., Shen B. B., Duan Z.H., Li X. A meta-analysis of the relation of polymorphism at sites− 1082 and− 592 of the IL-10 gene promoter with susceptibility and clearance to persistent hepatitis B virus infection in the Chinese population // Infection. 2011. Vol. 39(1). Р. 21-27.
References:
1. Bekenova N.B., Grjibovski A.M., Mukovozova L.A., Smail E.M., Tokaeva A.Z. Polimorfizm rs8193036 gena IL-17A v kazakhskoi populyatsii i ego svyaz' s produktsiei IL-17A u bol'nykh rozhei [rs8193036 polymorphism of IL-17A gene in a Kazakh population and its association with plasma IL-17A among erysipelas patients]. Ekologiya cheloveka [Human Ecology]. 2016. No. 4. PP.50-55. [in Russian]
2. Bekenova N.B., Grjibovski A.M., Mukovozova L.A., Aukenov N.E. Polimorfizm gena IL10 v polozhenii -1082G/A u bol'nykh rozhey [Polymorphism of IL10 gene at -1082G/A position in patients with erysipelas] Nauka i zdravookhranenie [Science & Healthcare]. 2016. No 3. PP. 34-45. [in Russian]
3. Berezhnaya N.M., Sepiashvili R.I. Semeystvo interleykinov-17 [Interlukin 17 family] Allergologiya i immunologiya [Allergology and immunology] 2010. No 3. PP.213-224.
4. Emel'yanova A.N., Vitkovskii Yu.A., Kizhlo L.B., Kalinina E.N. Prognosticheskoe znachenie geneticheskogo polimorfizma molekul Il-2 (T330G), Il-10 (S819T), Il-10 (G1082A) u bol'nykh rozhei v Zabaikal'skom krae [Prognostic significance of genetic polymorphism of IL-2 (T330G), IL-10 (C819T), IL-10 (G1082A) in patients with erysipelas in Transbaikal region] Dal'nevostochnyi zhurnal infektsionnoi patologii. 2012. No 21. PP. 159-163. [in Russian]
5. Emel'yanova A.N., Vitkovskiy Yu.A. Geneticheskiy polimorfizm IL-10 i CRP u bol'nykh s tsirrozom pecheni virusnoy etiologii [Polymorphism of genes IL-10 and CRP in patients with cirrosis of viral etiology] Sibirskiy meditsinskiy zhurnal (Irkutsk). 2013. No.119. pp.39-41 [in Russian]
6. Emel'yanova A.N., Vitkovskii Yu.A. Polimorfizm genov tsitokinov IL-2 (T330G), IL10 (S819T) i IL-10 (G1082A) pri khronicheskom virusnom gepatite S [Polymorphism of genes of cytokines of IL-2 (T330G), IL-10 (C819T) and IL10 (G1082A) in chronic virus hepatitis C] Molekulyarnaya meditsina. [Molekular medicine] 2013. No. 3. PP. 46-48. [in Russian]
7. Rizvanova F. F. i dr. Geneticheskaya diagnostika: polimorfizm genov tsitokinov [Genetic diagnosis: polymorphism of cytokine genes]. Prakticheskaya meditsina [Practical medicine] 2010. No. 6. PP.41-43.
8. Simbirtsev A.S., Gromova A.Yu. Funktsional'nyy polimorfizm genov regulyatornykh molekul vospaleniya [Functional gene polymorphisms of the molecules regulating inflammation] Tsitokiny i vospalenie. [Cytokines and inflammation] 2005. No 1. PP. 3-10. [in Russian]
9. Kholmatova K.K., Khar'kova O.A., Grzhibovskiy A. M. Klassifikatsiya nauchnykh issledovaniy v zdravookhranenii [Tipes of reaserch in health sciences]. Ekologiya cheloveka [Human Ecology]. 2016. № 1. pp.57-64.
10. Kholmatova K.K., Gorbatova M.A., Khar'kova O.A., Grzhibovskiy A.M. Poperechnye issledovaniya: planirovanie, razmer vyborki, analiz dannykh [Cross-sectional studies: planning, sample size, data analysis]. Ekologiya cheloveka [Human Ecology]. 2016. No 2. pp. 49-56.
11. Kholmatova K. K., Grzhibovskiy A. M. Primenenie issledovaniy «Sluchay-kontrol'» v meditsine i obshchestvennom zdravookhranenii. [Case-control studies in medicine and public health]. Ekologiya cheloveka. [Human Ecology]. 2016. No. 8. pp.53-60.
12. Afzal M.S., Tahir S., Saiman A., Baig T.A., Shafi T., Zaidi N., Qadri I. Analysis of interleukin-10 gene polymorphisms and hepatitis C susceptibility in Pakistan. The Journal of Infection in Developing Countries. 2011. Vol.06. pp. 473-479.
13. Brooks D.G, Trifilo M., Edelmann K., Teyton L.Mc., Gavern D.B., Oldstone M.B. Interleukin-10 determines viral clearance or persistence in vivo. Nature medicine. 2006, 12(11). pp. 1301-1309.
14. da Silva N. M, Germano F.N, Vidalez –Braz B.M, Carmo Zanella Rd, dos Santos D.M, Lobato R, de Martinez A.M. Polymorphisms of IL-10 gene in patients infected with HCV under antiviral treatment in southern Brazil. Cytokine. 2015, 73(2). pp. 253-257.
15. Dong C. Regulation and pro‐inflammatory function of interleukin‐17 family cytokines. Immunological reviews. 2008. Vol. 1. pp. 80-86.
16. Hu Y., Wu L., Li D., Zhao Q., Zhang W., Xu B. Association between cytokine gene polymorphisms and tuberculosis in a Chinese population in Shanghai: a case–control study. BMC immunology. 2015. Vol. 16(1). pp. 1-10.
17. Haukim N., Bidwell J.L., Smith A.J., Keen L.J., Gallagher G., Kimberly R., Huizinga T., McDermott M.F., Oksenberg J., McNicholl J., Pociot F., Hardt C., DAlfonso S. Cytokine gene polymorphism in human disease: on-line databases, supplement 2. Genes and immunity. 2002. Vol. 6. pp. 313-330.
18. Hayashi R., Tahara T., Shiroeda H., Saito T., Nakamura N., Tsutsumi M., Shibata T., Arisava T. Influence of IL17A polymorphisms (rs2275913 and rs3748067) on the susceptibility to ulcerative colitis. Clinical and experimental medicine. 2013, 13(4). pp. 239-244.
19. Ishida C., Ikebuchi Yu., Kinya O., Murawaki Y. Functional gene polymorphisms of interleukin-10 are associated with liver disease progression in Japanese patients with hepatitis C virus infection. Internal Medicine. 2011. Vol. 50 (7). pp. 659-666.
20. Joshi L., Ponnana M., Sivangala R., Chelluri L.K., Nallari P., Penmetsa S., Valluri V., Gaddam S. Evaluation of TNF-α, IL-10 and IL-6 cytokine production and their correlation with genotype variants amongst tuberculosis patients and their household contacts. PloS one. 2015. Vol. 10(9). pp.1-15.
21. Li N., Zhu Q., Li Zh., Han Q., Zhang G., Chen J., Xing F., Chen Y., Zeng X., Liu J. IL17A gene polymorphisms, serum IL‐17A and IgE levels, and hepatocellular carcinoma risk in patients with chronic hepatitis B virus infection. Molecular carcinogenesis. 2014. Vol. 6. pp. 447-457.
22. Liu Y. et al. Genetic variants in IL1A and IL1B contribute to the susceptibility to 2009 pandemic H1N1 influenza A virus. BMC immunology. 2013. Vol. 1. pp. 1-10.
23. McGuire W., Hill A.V., Allsopp C.E., Greenwood B.M, Kwiatkowski D. Variation in the TNF-α promoter region associated with susceptibility to cerebral malaria. Nature. 1994, 371(6497). pp. 508-511.
24. Meenakshi P., Ramya S., Shruthi T., Lavanya J., Mohammed H.H., Vijayalakshmi V., Sumanlatha G. Association of IL‐1β+ 3954 C/T and IL‐10‐1082 G/A Cytokine Gene Polymorphisms with Susceptibility to Tuberculosis. Scandinavian journal of immunology. 2013, 78(1). pp. 92-97.
25. Mira J.P., Cariou A., Grall F., Delclaux C., Losser M.R., Heshmati F., Cheval C., Monchi M., Teboul J.L., Riché F., Leleu G., Arbibe L., Mignon A., Delpech M., Dhainaut J.F. Association of TNF2, a TNF-α promoter polymorphism, with septic shock susceptibility and mortality: a multicenter study. Jama. 1999, 282(6). pp. 561-568.
26. Mosaad Y.M., Soliman O.E., Tawhid Z. E., Sherif D.M. Interferon‐gamma+ 874 T/A and Interleukin‐10‐1082 A/G Single nucleotide Polymorphism in Egyptian Children with Tuberculosis. Scandinavian journal of immunology. 2010, 72(4). pp. 358-364.
27. Nadel S., Newport M.J., Booy R., Levin M. Variation in the tumor necrosis factor-α gene promoter region may be associated with death from meningococcal disease. Journal of Infectious Diseases. 1996, 174(4). pp. 878-880.
28. Nakada T., Russell J., Boyd J.,and Walley K. Association analysis of the interleukin 17A gene in Caucasian rheumatoid arthritis patients from Norway and New Zealand. Rheumatology. 2009, 48(4). pp. 367-370.
29. Ocejo-Vinyals J., de Mateo E., Hoz M. The IL-17 G-152A single nucleotide polymorphism is associated with pulmonary tuberculosis in northern Spain. Cytokine. 2013. Vol.1. pp.58–61.
30. Pereira V.A., Sánchez-Arcila J.C., Teva A., Perce-da-Silva D.S., Vasconcelos M.P., Lima C.A., Aprígio C.J., Rodrigues-da-Silva R.N., Santos D.O., Banic D.M., Bonecini-Almeida M.G., Lima-Júnior J.C., Oliveira-Ferreira J. IL10A genotypic association with decreased IL-10 circulating levels in malaria infected individuals from endemic area of the Brazilian Amazon. Malaria journal. 2015, 28(14). pp. 1-12.
31. Rafiei A. et al. Polymorphism in the interleukin-17A promoter contributes to gastric cancer. World J Gastroenterol. 2013. Vol.34. pp. 5693-5699.
32. Ramos J.A., Silva R., Hoffman L., Ramos A.L., Cabello P.H., Ürményi T.P., Villella-Nogueira C.A., Lewis-Ximenez L., Rondinelli E. Association of IL-10, IL-4, and IL-28B gene polymorphisms with spontaneous clearance of hepatitis C virus in a population from Rio de Janeiro. BMC research notes. 2012. Vol. 5(1).pp. 1-6.
33. Sepahi S., Pasdar A., Ahadi M., Gerayli S., Rostami S., Meshkat Z. Haplotype Analysis of Interleukin-10 Gene Promoter Polymorphisms in Chronic Hepatitis C Infection: A Case Control Study. Viral immunology. 2014, 27(8). pp. 398-403.
34. Sodsai P. Surakiatchanukul T., Kupatawintu P., Tangkitvanich P., Hirankarn N. Association of cytokine and cytokine receptor gene polymorphisms with the risk of chronic hepatitis B. Asian Pacific Journal of Allergy and Immunology. 2013, 31(4). pp. 277-285.
35. Stappers M., Thys Y., Oosting M., Plantinga T., Ioana M., Reimnitz P., Mouton J., Netea M., Joosten L. Polymorphisms in cytokine genes IL6, TNF, IL10, IL17A and IFNG influence susceptibility to complicated skin and skin structure infections. European Journal of Clinical Microbiology & Infectious Diseases. 2014, 33(12). pp 2267-2274.
36. Tarhuni A. et al. Impact of cytokine gene variants on the prediction and prognosis of hepatocellular carcinoma in patients with cirrhosis. Journal of hepatology. 2014. Vol. 2. pp. 342-350.
37. Tunçbilek S. Relationship between cytokine gene polymorphisms and chronic hepatitis B virus infection. World journal of gastroenterology: WJG. 2014. Vol. 20. pp. 6226-6235.
38. Wang J., Liu Y., Xie L., Li S., Qin X. Association of IL-17A and IL-17F gene polymorphisms with chronic hepatitis B and hepatitis B virus-related liver cirrhosis in a Chinese population: A case-control study. Clinics and research in hepatology and gastroenterology. 2016. Vol. 40 (3).pp. 288-296.
39. Wang J., Liu Y., Xie L., Li S., Qin X. Interleukin-10 promoter polymorphisms in patients with hepatitis B virus infection or hepatocellular carcinomain Chinese Han ethnic population. Hepatobiliary Pancreat Dis Int. 2005. Vol. 1. pp. 60-64.
40. Wang J., Shyur S., Wang W., Liou Y., Lin C., Wu Y., Wu L. The polymorphisms of interleukin 17A (IL17A) gene and its association with pediatric asthma in Taiwanese population. Allergy. 2009. Vol. 64(7). pp. 1056-1060.
41. Yee L.J., Tang J., Herrera J., Kaslow R. A., van Leeuwen D.J. Tumor necrosis factor gene polymorphisms in patients with cirrhosis from chronic hepatitis C virus infection. Genes and immunity. 2000, 1(6). pp. 386-390.
42. Zhang G. et al. Allele-specific induction of IL-1β expression by C/EBPβ and PU. 1 contributes to increased tuberculosis susceptibility. PLoS Pathog. 2014. Vol.10. pp.1-15.
43. Zhang T.C, Pan F.M., Zhang L. Z., Gao Y.F., Zhang Z.H., Gao J., Ge R., Mei Y., Shen B.B., Duan Z.H., Li X. A meta-analysis of the relation of polymorphism at sites− 1082 and− 592 of the IL-10 gene promoter with susceptibility and clearance to persistent hepatitis B virus infection in the Chinese population. Infection. 2011, 39(1). pp. 21-27.
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Бекенова Н.Б., Гржибовский А.М., Муковозова Л.А. Ассоциация полиморфизмов генов цитокинов ИЛ1В (rs1143627), ИЛ10 (rs1800896), ИЛ17А (rs 2275913, rs8193036) с инфекционными заболеваниями, в том числе и рожей / / Наука и Здравоохранение. 2016. №4. С. 104-118. Bekenova N.B., Grjibovski A.M., Mukovozova L.A. Association of polymorphisms of genes of IL1B(rs1143627), IL10 (rs1800896), IL17А (rs 2275913, rs8193036) with infectious diseases including erysipelas. Nauka i Zdravookhranenie [Science & Healthcare]. 2016, 4, pp. 104-118. Бекенова Н.Б., Гржибовский А.М., Муковозова Л.А ИЛ1В (rs1143627), ИЛ10 (rs1800896), ИЛ17А (rs 2275913, rs8193036) гендер полиморфизмдерінің жұқпалы аурулармен, оның ішінде тілме ауруымен байланысы / / Ғылым және Денсаулық сақтау. 2016. №4. Б. 104-118.Related publications:
INTERRELATION OF INTRAABDOMINAL HYPERTENSION AND MARKERS OF GASTROINTESTINAL TRACT INJURY IN PATIENTS WITH MULTIORGAN DYSFUNCTION
DRUG-INDUCED LIVER INJURY AND GENDER DIFFERENCES
QUALITY OF LIFE IN PRIMARY BILIARY CHOLANGITIS AND ITS ASSESSMENT
DIAGNOSTIC AND THERAPEUTIC LAPAROSCOPY FOR ABDOMINAL INJURIES. REVIEW
METHODS FOR SCHOOL-AGE CHILDREN NUTRITIONAL STATUS ASSESSMENT: FOCUS ON ANTHROPOMETRIC PARAMETERS. A REVIEW.