Online ISSN: 3007-0244,
Print ISSN:  2410-4280
Relevance: Chorioncarcinoma is a rare malignant trophoblastic tumor that has an aggressive course, progresses rapidly and metastases early, unfortunately, it is diagnosed late. Chorioncarcinoma is often an accidental finding, limited to the placenta, with no signs of spreading to the mother or child's body, but sometimes it is diagnosed late and in the presence of multiple metastases. Aim. is to familiarize with the features of the morphological diagnosis of chorioncarcinoma. Methods: The article describes a clinical case of a patient with chorioncarcinoma of the uterus. The data of a pathomorphological study are presented. Results: This clinical case demonstrates that when a proliferating trophoblast without chorial villi is detected 2-3 months later or later after childbirth or abortion, it is necessary to take into account the possibility of a malignant tumor of the trophoblast, which requires caution during histological examination of surgical biopsy material. Conclusion: Although the frequency of postpartum choriocarcinoma is extremely low, for early diagnosis of postpartum choriocarcinoma and improvement of prognosis, a thorough postpartum histological examination of the placenta and monitoring of the level of beta-human chorionic gonadotropin in the blood of pregnant women and high-risk women is necessary.
Maida M. Tussupbekova1, Leila M. Stabayeva1, Gulnazira N. Imanbayeva1, Raikhan Zh. Nygyzbayeva1, Sabina S. Abieva1, NCJSC «Karaganda Medical University», Department of Pathology, Karaganda c., the Republic of Kazakhstan.
1. Кондриков Н.И., Баринова И.В. Патология матки: руководство для врачей. – 2-е изд. – М.: Практическая медицина, 2019. – 352 с. (Дата обращения: 12.02.2023) 2. Солопова А.Г., Макацария А.Д., Солопова А.Е., Егорова Е.С., Москвичёва В.С. Гестационная трофобластическая болезнь: факторы риска, современные методы диагностики и лечения // Акушерство, гинекология и репродукция. 2018. №2. С. 48-54. 3. Lok C., Frijstein M., van Trommel N. Clinical presentation and diagnosis of Gestational Trophoblastic Disease // Best Pract Res Clin Obstet Gynaecol. 2021 Jul. -74.-P. 42-52. doi: 10.1016/j.bpobgyn.2020.12.001. Epub 2020 Dec 21. PMID: 33422446. 4. Mangla M., Singla D., Kaur H., Sharma S. Unusual clinical presentations of choriocarcinoma: A systematic review of case reports // Taiwan J Obstet Gynecol. 2017. 56(1). P.1-8. doi: 10.1016/j.tjog.2015.05.011. PMID: 28254207. References: 1. Kondrikov N.I., Barinova I.V. Patologiya matki: rukovodstvo dlya vrachei. 2-e izd. M.: Prakticheskaya meditsina [Pathology of the uterus: a guide for doctors. M.: Practical Medicine], 2019. 352 p. (accessed: 12.02.2023) 2. Solopova A.G., Makatsariya A.D., Solopova A.E., Egorova E.S., Moskvicheva V.S. Gestatsionnaya trofoblasticheskaya bolezn': faktory riska, sovremennye metody diagnostiki i lecheniya [Gestational trophoblastic disease: risk factors, modern methods of diagnosis and treatment]. Akusherstvo, ginekologiya i reproduktsiya [Obstetrics, gynecology and reproduction]. 2018. №2. pp. 48-54. (accessed: 12.02.2023)
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Category of articles: Clinical case

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Tussupbekova M.M., Stabayeva L.M., Imanbayeva G.N., Nygyzbayeva R.Zh., Abieva S.S. Morphological substantiation of a trophoblastic tumor // Nauka i Zdravookhranenie [Science & Healthcare]. 2023, (Vol.25) 4, pp. 282-286. doi 10.34689/SH.2023.25.4.035

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