ACTUAL PROBLEMS OF THE USE MODERN INTRAMEDULLARY TELESCOPIC RODS USED IN THE SURGICAL TREATMENT OF OSTEOGENESIS IMPERFECTA IN CHILDREN. REVIEW.
Topicality. Children with osteogenesis imperfecta suffer from bone fragility, increased joint mobility and a number of different soft tissue defects. Treatment includes surgical and medical treatment of skeletal abnormalities and treatment of other complications. More innovative approaches based on gene and cell therapy and changes in signaling pathways are under study. Various systems of telescopic intramedullary rods have been developed, each of which has its own characteristics and technical difficulties. Bisphosphonates remain the basis of treatment for these patients. Orthopedic surgical treatment using intramedullary fixation for the treatment of deformity of long bones and prevention of future fractures is dynamically developing in many countries, including ours. Unfortunately, intramedullary fixation of long tubular bones in children with osteogenesis imperfecta has also demonstrated a high incidence of complications and repeated operations. Surgery of patients with OI is a difficult task. Orthopedic surgeons should strive to minimize complications and the frequency of revisions when using telescopic intramedullary rods. Thus, the following arrangements should try to eliminate these complications and the quality of life of a child with osteogenesis imperfecta and the parents who care for them.
Objective. Analysis of the problems of the use of modern intramedullary telescopic devices used in the surgical treatment of osteogenesis imperfecta in children according to modern literature.
Search strategy. The study examined full-text publications in English and Russian, which are devoted to surgical treatment of children with IO in foreign countries. In the process of literature search, the following search engines were used:Pubmed, Web of science, Cyberleninka, Google Scholar by keywords. Publications from 2014 to 2022 were studied and analyzed, the articles were mostly foreign and in English.120 publications have been identified on this topic. Of these, 83 publications corresponded to the purpose of our study.Inclusion criteria: Publications of the level of evidence A, B: meta-analyses, systematic reviews, cohort and crosssectional studies. Exclusion criteria: summary reports, newspaper articles and personal messages
Results and conclusions. Surgical treatment of children with osteogenesis imperfecta directed at correcting the deformation of long bones and preventing future fractures with the help of telescopic intramedullary rods is dynamically developing in the world. However, given the complications that arise after the installation of devices, future telescopic intramedullary implants should be based on improving the quality of life of children with OI and preventing possible complications.
Altyngul Khassenkyzy1,
Bolatbek A. Dossanov1, https://orcid.org/0000-0001-9816-7404
Asem K. Dossanova1, https://orcid.org/0000-0002-6391-4083
1 NCJSC“ Astana Medical university”, Department of Pediatric Surgery,
Astana, Republic of Kazakhstan.
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Khassenkyzy A., Dossanov B.A., Dossanova A.K. Actual problems of the use modern intramedullary telescopic rods used in the surgical treatment of osteogenesis imperfecta in children. Review // Nauka i Zdravookhranenie [Science & Healthcare]. 2023, (Vol.25) 5, pp. 199-208. DOI 10.34689/SH.2023.25.5.026Related publications:
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ACTUAL PROBLEMS OF THE USE MODERN INTRAMEDULLARY TELESCOPIC RODS USED IN THE SURGICAL TREATMENT OF OSTEOGENESIS IMPERFECTA IN CHILDREN. REVIEW.