VARIANT OF ADULT-ONSET STILL’SDISCASE: CASE REPORT
Currently, Still's disease in adults is a rare disease of unknown etiology that does not have specific clinical symptoms, with different pathogenetic mechanisms for the development of the pathological process in different age groups, which creates a variety of clinical options for the course of this disease; as a result, drug methods still remain an incompletely solved problem. Therapy and prediction of the course of Still's disease in adults, no proven methods of primary prevention have been developed on a global scale.
Over the past 3 decades, modern scientific medical literature has described sporadic cases of these diseases, indicating various empirically selected drugs that had a positive effect, stopping the disease or achieving remission.
The study of various pathogenetic and clinical aspects of Still's disease in adults is necessary for doctors of many specialties, since to date a large amount of clinical material has accumulated, indicating a very slow, but still increasing prevalence of this disease throughout the world.
The presented article describes a clinical case of Still's disease in adults, in which, along with typical criteria, there were rare symptoms that highlight the peculiarity of this case history, and also describes the positive therapeutic effect of using interleukin-6 inhibitors as pathogenetic therapy.
Alida Sh. Kaskabayeva1, https://orcid.org/0000-0002-5184-214X
Gulzhakan K. Kapanova1, https://orcid.org/0000-0001-6574-6581
Ainur S. Botabaeva1, https://orcid.org/0000-0003-1391-8294
Anis K. Bekisheva2
1 NJSC "Semey Medical University", The department of internal medicine and rheumatology,
Semey c., Republic of Kazakhstan;
2 The University Hospital of the NJSC "Semey Medical University", Cardiorheumatological department,
Semey c., Republic of Kazakhstan;
1. Asherson R., Pascoe Z. Adult onset Still’s disease: response to Enbrel Ann Rheum Dis. 2002. 61:28:452-454.
2. Fautrel B., Zing E., Golmard J., et.al. Proposal for a New set of classification criteria for adult onset Still’s disease // Medicine, 2002. 81:194-200.
3. Hoshino T., Ohta A., Yang D., et al. Elevated serum interleirin-6, interferon – and tumor necrosis factor – a levels in patients with adult onset Still’s disease // J. Rheumatol., 1998. 25:396-398.
4. Koizumi R., Tsurada Y, et.al. Treatment of adult Still’s disease with dexemetazone, an alternative to prednisolone // Scand J. Rheumatol 2000. 29:396-398.
5. Mok C., Lan C., Wong R. Clinical characteristics? Treatment and outcome of adult onset Still’s disease in Southern Chinese // J. Rheumatol., 1998. 25:2345-2351.
6. Pouchot J., Sampalis J., Beadet F., et.al. Adult Still’s disease: Manifestations, disease courge, anl outcome in 62 patients // Medicine, 1991. 70:118-136/
7. Yamaguchi M., Ohta A., et.al. Preliminary critesia for classification of adult Still’s disease // J. Rheumatol., 1992. 19:424-430.
8. Yoroyama M., Suna A., Shinozawa T. et.al. A case of adult onset Still’s disease complica ted with adult respiratory disotress syndrome and disseminated intravascular coagulation // Jpn J. ClinImmunol., 1995. 18:207-214.
Number of Views: 72
Category of articles:
Clinical case
Bibliography link
Kaskabayeva A.Sh., Kapanova G.K., Botabaeva A.S., Bekisheva A.K. Variant of adult-onset Still’sdiscase: case report // Nauka i Zdravookhranenie [Science & Healthcare]. 2023, (Vol.25) 6, pp. 271-274. doi 10.34689/SH.2023.25.6.029Related publications:
RABIES - AN INFECTIOUS DISEASE WITH A FATAL OUTCOME (CLINICAL CASE)
ACTIVATION OF OPPOSITE PROCESSES – OSTEOPOROSIS AND OSTEOGENESIS IN ANKYLOSING SPONDYLITIS USING THE CLINICAL CASES
GRANULOMATOUS POLYANGITIS (WEGENER’S GRANULOMATOSIS) IN THE PRACTICE OF A RHEUMATOGIST
VARIANT OF ADULT-ONSET STILL’SDISCASE: CASE REPORT
A CASE OF DÜHRING'S DERMATITIS HERPETIFORMIS ASSOCIATED WITH SARS - COV - 2