IN-STENT THROMBOSIS AND RESTENOSIS OF THE CORONARY ARTERIES IN PATIENTS WITH CORONARY HEART DISEASE AFTER CORONAVIRUS INFECTION
Introduction. Coronavirus infection (CVI) has made a significant contribution to the course of cardiovascular diseases in the population of almost all countries of the world. The peculiarities of this course during the COVID-19 pandemic were delayed medical care for patients with acute coronary syndrome and myocardial infarction due to insufficient resources for external care, hospital beds, shortage of ambulance crews, and means for resuscitative measures
The aim is to analyze the characteristics of in-stent thrombosis and restenosis of the coronary arteries in patients with coronary heart disease who suffered coronavirus infection.
Materials and methods. The study included 490 individuals who underwent repeated myocardial revascularization due to thrombosis of a previously implanted coronary artery stent or its restenosis. The main study group consisted of 181 patients who had a documented coronavirus infection. The control group included 309 patients of both sexes with revascularized coronary heart disease who had no history of coronavirus infection. The age of the patients is 34-87 years. The results obtained were analyzed using a specially created Register, which included all patients who underwent myocardial revascularization between March 2020 and 2023 after CVI
Results. People with acute coronary syndrome due to or after a coronavirus infection are significantly more likely to develop myocardial infarction compared to people who have not had an infection; among them, adverse outcomes in the form of death or transfer to other medical institutions due to the severity of the condition are statistically significantly more common. Among people in the main group, sub-acute thrombosis inside the stent was significantly more common.
Conclusion. It is necessary to carefully study the role of CVI in the development of coronary artery thrombosis in order to be prepared to provide timely and most effective medical care to patients.
Gulnara B. Batenova1, https://orcid.org/0000-0003-3198-1860
Lyudmila M. Pivina1, https://orcid.org/0000-0002-8035-4866
Yersin Т. Sabitov2, https://orcid.org/0000-0003-0937-5813
Evgeny I. Dedov3, https://orcid.org/0000-0002-9118-3708
Diana G. Ygiyeva1, https://orcid.org/0000-0001-8391-8842
Ulzhan S. Jamedinova1, https://orcid.org/0000-0003-1671-289X
Galiya А. Аlibayeva2, https://orcid.org/0000-0002-1503-4663
Zhansaya Т. Aukenova1, https://orcid.org/0009-0001-3591-8175
Assylzhan М. Messova1, https://orcid.org/0000-0001-5373-0523
Maksim R. Pivin1, https://orcid.org/ 0000-0001-7206-8029
Zhanar М. Urazalina1, https://orcid.org/0000-0002-4494-6565
Saltanat М. Adilgozhina1, https://orcid.org/0000-0002-8408-7363
Alida Sh. Kaskabayeva1, https://orcid.org/0000-0002-5184-214X
Zhanna Ye. Musdubayeva1, https://orcid.org/0000-0002-9058-1878
1 Semey Medical University, Semey, Republic of Kazakhstan;
2 Emergency Hospital, Semey, Republic of Kazakhstan;
3 Russian National Research Medical University named after. N.I. Pirogov, Moscow, Russian Federation.
1. Alekyan B.G., Boytsov S.A., Ganyukov V.I., Manoshkina E.M. Impact of the COVID-19 Pandemic on Myocardial Revascularization in Patients with Acute Coronary Syndrome in the Russian Federation // Rational Pharmacotherapy in Cardiology 2022. V. 18(4). P. 411-419.
2. American College of Surgeons. COVID‐19: Guidance for Triage of Non‐Emergent Surgical Procedures: Elective Surgery Acuity Scale (ESAS). 2020. 227p.
3. Angelillis M., De Carlo M., Christou A., Marconi M., Mocellin D.M., Caravelli P., De Caterina R., Petronio A.S. A case report of multisite arterial thrombosis in a patient with coronavirus disease 2019 (COVID-19) // Eur Heart J Case Rep. 2020. V. 5(1). P. 339.
4. Antuña P., Rivero F., Del Val D., Cuesta J., Alfonso F. Late Coronary Stent Thrombosis in a Patient With Coronavirus Disease 2019 // JAMA Cardiol. 2020. V. 5(10). P. 1195-1198.
5. Ayan M., Kovelamudi S., Al-Hawwas M. Subacute stent thrombosis in a patient with COVID-19 pneumonia // Proc (Bayl Univ Med Cent). 2020. V. 34(1). P. 175-177.
6. Beun R., Kusadasi N., Sikma M., Westerink J., Huisman A. Thromboembolic events and apparent heparin resistance in patients infected with SARS-CoV-2 // Int J Lab Hematol. 2020. V. 42. P. 19-20.
7. Choudhary R., Kaushik A., Sharma J.B. COVID-19 pandemic and stent thrombosis in a post percutaneous coronary intervention patient-a case report highlighting the selection of P2Y12 inhibitor // Cardiovasc Diagn Ther. 2020.
8. Choudry F.A., Hamshere S.M., Rathod K.S. High thrombus burden in patients with COVID-19 presenting with ST-elevation myocardial infarction // J Am Coll Cardiol 2020. V. 6. P. 1168-76.
9. COVIDSurg Collaborative, GlobalSurg Collaborative. Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study // Anaesthesia. 2021. V. 76. P. 748–758.
10. Elkholy K.O., Khizar A., Khan A., Hakobyan N., Sahni S. Subacute Stent Thrombosis in a Patient With COVID-19 Despite Adherence to Antiplatelets // Cureus. 2021. V. 13(2).
11. Galeazzi G.L., Loffi M., Di Tano G. Severe COVID-19 pneumonia and very late stent thrombosis: a trigger or innocent bystander? // Korean Circ J. 2020. V. 50. P. 632–3.
12. Gallo G., Calvez V., Savoia C. Hypertension and COVID-19: Current Evidence and Perspectives // High Blood Press Cardiovasc Prev. 2022. V. 29(2). P. 115-123.
13. Gori T., Polimeni A., Indolfi C., Räber L., Adriaenssens T., Münzel T. Predictors of stent thrombosis and their implications for clinical practice // Nat Rev Cardiol. 2019. V. 16(4). P. 243-256.
14. Hannan E.L., Wu Y., Cozzens K., Friedrich M., Tamis-Holland J., Jacobs A.K. et all. Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction Before and During COVID in New York // Am J Cardiol. 2021. V. 1.P. 25-34.
15. Karic A., Haxhibeqiri-Karabdic I., Kabil E., Grabovica S., Straus S., Busevac E., Krajinovic A., Banjanovic B., Djedovic M., Granov N. Left Ventricular Free Wall Rupture After Acute Myocardial Reinfarction Due to In-Stent Thrombosis in COVID-19 Patient // Acta Inform Med. 2022. V. 30(1). P. 76-80.
16. Kiss P., Carcel C., Hockham C., Peters S. The impact of the COVID‐19 pandemic on the care and management of patients with acute cardiovascular disease: a systematic review // Eur Heart J Qual Care Clin Outcomes. 2021. V. 7(1). P. 18‐27.
17. Kunal S., Pathak V., Pathak K., Mishra M., Sharma S.M., Bhandari S. Very late stent thrombosis associated with COVID-19 infection: a case report and review of the literature // Monaldi Arch Chest Dis. 2021. V. 92(2).
18. Rahman T., Alayo Q.A., Chaudhary S.G., Moghadam R.C., German M.L., Ettinger N.A. STEMI associated with SARS-CoV-2 infection and the use of ECMO as a potential therapeutic approach in addition to the PCI // Oxf Med Case Reports. 2021. V. 2021(3). P. 148.
19. Semenova Y., Pivina L., Khismetova Z., Auyezova A., Nurbakyt A., Kauysheva A., Ospanova D., Kuziyeva G., Kushkarova A., Ivankov A., Glushkova N. Anticipating the Need for Healthcare Resources Following the Escalation of the COVID-19 Outbreak in the Republic of Kazakhstan // J Prev Med Public Health. 2020. V. 53(6). P. 387-396.
20. Yammine L., Frazier L. Comparison of demographic, psychosocial, and clinical characteristics among younger and older persons with acute coronary syndrome // J Am Assoc Nurse Pract. 2013. V. 25(2). P. 103-8.
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Batenova G.B., Pivina L.M., Sabitov Ye.Т., Dedov E.I., Ygiyeva D.G., Jamedinova U.S., Аlibayeva G.А., Aukenova Zh.Т., Messova A.М., Pivin M.R., Urazalina Zh.М., Adilgozhina S.М., Kaskabayeva A.Sh., Musdubayeva Zh.Ye. In-stent thrombosis and restenosis of the coronary arteries in patients with coronary heart disease after coronavirus infection // Nauka i Zdravookhranenie [Science & Healthcare]. 2024, (Vol.26) 1, pp. 118-124. doi 10.34689/SH.2024.26.1.015Related publications:
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