DESCRIPTION OF A CLINICAL CASE OF GENERALIZED LYMPHADENOPATHY OF UNKNOWN ETIOLOGY
Lymph nodes are small glands needed to filter fluid from the lymphatic system. Lymphadenopathy is a palpable enlargement of a lymph node with a diameter of more than 1 cm. Etiology includes infectious and autoimmune diseases, malignant neoplasms, lymphoproliferative disorders, and taking certain medications. Lymphadenopathy can be generalized and localized.
Often, patients are unaware of enlarged lymph nodes and lymphadenopathy is detected by a doctor during an objective examination. Generalized lymphadenopathy, with lesions 2 or more groups of lymph nodes may indicate an underlying cancer or systemic disease.
The article presents a case of generalized lymphadenopathy of unknown etiology, which was accompanied by polyserositis and other clinical manifestations indicating the presence of an underlying oncological or systemic disease.
Farida Y. Rustamova1, https://orcid.org/0000-0002-5259-6171
Raikhan U. Mukhambetova2,
Shakhnaz I. Iminova1, https://orcid.org/0009-0008-5047-4155
Aisha Y. Baimolda1, https://orcid.org/0009-0007-2026-1389
Nargiz A. Abdykhalyk1, https://orcid.org/0009-0007-0871-3792
Shyngys Y. Skakbayev1, https://orcid.org/0009-0008-6916-6777
1. Ali M., Elhatw A., Hegazy M., Albeyoumi H., Sakr N., Deyab A.M., Soliman A.Y., Said E., Samir Elbehwashy A., Nassar M., Alfishawy M. The Evaluation of Lymphadenopathy in a Resource-Limited Setting. Cureus. 2022 Oct 24. 14(10):e30623. doi: 10.7759/cureus.30623. PMID: 36426328. PMCID: PMC9681672.
2. Costagliola G., Consolini R. Lymphadenopathy at the crossroad between immunodeficiency and autoinflammation: An intriguing challenge. Clin Exp Immunol. 2021 Sep. 205(3):288-305. doi: 10.1111/cei.13620. Epub 2021 Jun 20. PMID: 34008169. PMCID: PMC8374228.
3. Ferrer R. Lymphadenopathy: differential diagnosis and evaluation. Am Fam Physician. 1998 Oct 15. 58(6):1313-20. PMID: 9803196.
4. Gaddey H.L., Riegel A.M. Unexplained Lymphadenopathy: Evaluation and Differential Diagnosis. Am Fam Physician. 2016 Dec 1. 94(11):896-903. PMID: 27929264.
5. Mohseni S., Shojaiefard A., Khorgami Z., Alinejad S., Ghorbani A., Ghafouri A. Peripheral lymphadenopathy: approach and diagnostic tools. Iran J Med Sci. 2014 Mar. 39(2 Suppl):158-70. PMID: 24753638. PMCID: PMC3993046.
6. Richner S., Laifer G. Peripheral lymphadenopathy in immunocompetent adults. Swiss Med Wkly. 2010 Feb 20. 140(7-8):98-104. doi: 10.4414/smw.2010.12892. PMID: 20069473.
7. Heidi L.. Unexplained Lymphadenopathy: Evaluation and Differential Diagnosis Am Fam Physician. 2016;94(11):896-903
8. Савина Т.А. Лимфаденопатии различной этиологии в клинике туберкулеза периферических лимфатических узлов. Дисс.докт.мед.наук. Москва, 1997; с. 450.
Number of Views: 191
Bibliography link
Rustamova F.Y., Mukhambetova R.U., Iminova Sh.I., Baimolda A.Y., Abdykhalyk N.A., Skakbayev Sh.Y. Description of a clinical case of generalized lymphadenopathy of unknown etiology // Nauka i Zdravookhranenie [Science & Healthcare]. 2024. Vol.26 (5), pp. 230-235. doi 10.34689/SH.2024.26.5.027Related publications:
VIRAL HEPATITIS IN KAZAKHSTAN: REGIONAL EPIDEMIOLOGICAL OVERVIEW
PREDICTORS OF ANTIVIRAL THERAPY INEFFECTIVENESS IN CHRONIC HEPATITIS C: A MATCHED CASE-CONTROL STUDY IN ALMATY, A MAJOR METROPOLIS OF KAZAKHSTAN
МЕДИКО – СОЦИАЛЬНЫЕ ОСОБЕННОСТИ ПРИВЕРЖЕННОСТИ К ЛЕЧЕНИЮ БОЛЬНЫХ С ХРОНИЧЕСКИМ ПАНКРЕАТИТОМ
PATHOGENETIC ASSESSMENT OF CLINICAL AND INSTRUMENTAL PARAMETERS OF THE LUNGS IN PATIENTS WITH DIABETES MELLITUS
THE FREQUENCY AND EFFICACY ASSESSMENT OF RADIOIODINE THERAPY FOR DISTANT METASTASES OF THYROID CANCER