Online ISSN: 3007-0244,
Print ISSN:  2410-4280
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UPTAKE BARRIERS TO THE TREATMENT OF PRECANCEROUS CERVICAL DISEASES
Background. The malignant cervical tumors are the second leading cause of female mortality in the Republic of Kazakhstan. Currently, there is a growth of untreated precancerous cervical diseases which have a potential to develop into cervical cancer. In this connection, the question arises what barriers exist to the treatment of precancerous cervical diseases.

Objective: To identify uptake barriers to the treatment of precancerous cervical diseases.

Materials and methods. A cross-sectional study with random sampling strategy. Sampling - 404 women of childbearing age, ...
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2017 year | Issue: 1 | Pages: 122-132

ACCESSIBILITY IN THE ASSESSMENT OF PEOPLE WITH DISABILITIES
Background: Social protection of disabled persons has a special place in the government system of social support. In order to prepare the ground for the ratification by Kazakhstan of the Convention on the Rights of Persons with Disabilities Plan was developed to ensure the rights and improve the quality of life of people with disabilities in the years 2012-2018, which will improve the system of social protection and improve the efficiency of social services.

The aim of the research is to study satisfaction of disabled due to rheumatic diseases (RD) quality health and socia...
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2017 year | Issue: 1 | Pages: 112-121

VIDEO ENDOSCOPE TECHNOLOGY WITH MINIMALLY INVASIVE SURGICAL TREATMENT OF PATIENTS WITH CORONARY HEART DISEASE: CASE SERIES REPORT
Coronary artery bypass surgery with using endoscopic technology is the most recent trend of surgical treatment of coronary heart disease.

The purpose of this work is to present the experience of the 8 video assistant cardiac surgery in a "Pavlodar Regional Cardiological Center" for the period from 2012 to 2016.

Materials and methods. Design - case series. All 8 patients underwent minimal-ivasive direct coronary artery bypass off pump, with endoscopic release of the left internal mammary artery (LIMA), and making anastomosis LIMA to left anterior desc...
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2017 year | Issue: 1 | Pages: 87-96

COMMENTS ON 2016 EUROPEAN GUIDELINES FOR THE MANAGEMENT OF ATRIAL FIBRILLATION: NEW ASPECTS FOR PHYSICIANS
Updated European guidelines for the management of atrial fibrillation were published on the 27 of August, 2016. This document is remarkable for new recommendations, especially about anticoagulation therapy. Key points of these guidelines and the possibility of their use in our country are described in the article.

Objective: to find out essential evidence-based key points of the 2016 guidelines and to investigate the possibility of their use in Kazakhstan.

Materials and methods: To achieve these goals major differences between 2016, 2012, 2010 guidelines were analyze...
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2017 year | Issue: 1 | Pages: 74-86

IMMUNOHISTOCHEMICAL ANALYSIS EXPRESSION TP73 IN ONCOCYTIC FOLLICULAR ADENOMA OF THE THYROID
Oncocytic follicular adenomas (FAs) of the thyroid are cells neoplasms of follicular origin that predominantly consist of large polygonal cells with eosinophilic and granular cytoplasm. According to some scientific studies, TP73 might play a сertain role in tumor genesis (oncogenesis). Moreover, due to the absence of p53, oncogenes may attract p73 to induce apoptosis in tumor cells. TP53 is a crucial tumor suppressor in preventing the cancerous transformation of cells. There was also a particular focus on the amplification of 1p36 chromosome in oncocytic FA, which contains a t...
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2017 year | Issue: 1 | Pages: 64-73