Online ISSN: 3007-0244,
Print ISSN:  2410-4280
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MODELING OF TYPE 2 DIABETES MELLITUS IS A NECESSARY FOUNDATION FOR STUDY OF MEDICINAL PRODUCTS WITH ANTIDIABETIC POTENCY
Taking into account the worldwide increasing number of patients with type 2 diabetes mellitus, the actual problem of modern pharmacology continues to be the development of antidiabetic drugs with high therapeutic activity and having a better risk-benefit profile. In this connection diabetes modeling is very important, it allows reliably detect the presence of a particular pharmacological activity or new components in the mechanism of drugs action. Models of diabetes can be obtained from various species of animals spontaneously, induced by chemical diabetogenic substances, dietary or surgical p...
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2014 year | Issue: 4 | Pages: 4-8

SURGICAL RESTORATION OF CRUCIATE LIGAMENTS OF THE KNEE JOINT. HISTORICAL REPORT. (LITERATURE REVIEW)
The authors analyzed historical data on the operative restoration of cruciate ligaments of the knee joint. This is one of the actual problem of modern traumatology very difficult in surgical equivalent and still it isn't solved.
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2014 year | Issue: 3 | Pages: 15-17

TREATMENTS FRACTURES OF DISTAL METAEPIPHYSIS OF RADIAL BONE AT ADVANCED AGE. (LITERATURE REVIEW)
The authors analyzed data on the actual problems about fractures of distal metaepiphysis of radial bone at advanced age, epidemiology, diagnosis, analysis of ambulatory and surgical treatment. Also was performed medico-social side of this question.
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2014 year | Issue: 3 | Pages: 12-14

MOLECULAR GENETIC BASIS OF DIAGNOSIS AND CORONARY HEART DISEASE. (Literature review)
In the Republic of Kazakhstan circulatory system diseases represent one of the most actual health care problems and had been one of the leading places in the structure of mortality [1, 3]. On the basis of the development of multifactorial diseases, including cardiovascular disease (CVD) are genetic disorders like hereditary acquired, conditional on individual predisposition to disease and acquired by the individual as a result of the influence of external environmental factors. Most of these genetic disorders is represented by point mutations (mononukleoid polymorphisms) or une...
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2014 year | Issue: 3 | Pages: 4-11

РЕАБИЛИТАЦИЯ ПАЦИЕНТОВ С ХРОНИЧЕСКИМИ ЗАБОЛЕВАНИЯМИ ПЕЧЕНИ И МОНИТОРИНГ ЕЕ ЭФФЕКТИВНОСТИ В ЗОНЕ ПОВЫШЕННОГО РАДИАЦИОННОГО РИСКА В ВОСТОЧНО-КАЗАХСТАНСКОМ РЕГИОНЕ
Изучены особенности течения и патогенетические механизмы хронических заболеваний печени в экологически неблагоприятном регионе Восточного Казахстана, прилегающих к бывшему испытательному ядерному полигону. Определена структура патологии печени в регионе. Отмечены возможности неинвазивной оценки степени фиброзообразования посредством использования дискриминантной счетной шкалы в сопоставлении с показателями печеночной гемодинамики. Оценена эффективность реабилитации больных с патологией печени в регионе повы-шенного радиационного риска с мониторингом динамики индекса фиброза, определяющей сниже...
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2014 year | Issue: 2 | Pages: 13-15