Online ISSN: 3007-0244,
Print ISSN:  2410-4280
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ASSESSMENT OF TOXICITY OF NEOADJUVANT CHEMOTHERAPY FOR LOCALLY ADVANCED BREAST CANCER
Introduction. In the structure of malignancies in women breast cancer (BC) takes 1st place. In locally advanced breast cancer (LABC) treatment begins with neoadjuvant chemotherapy (CTX), the standard protocols are CMF, FAC, AC. In the trial, we used cytostatic Arglabin isolated from plants endemic to Central Kazakhstan - wormwood smooth, as monotherapy and as addition to AC-protocol.

The objective of the trial - to assess the toxicity of different protocols of neoadjuvant CTX of LABC.

Methods: 93 patients with LABC (T2N1-2M0, T3N0-2M0) ...
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2017 year | Issue: 1 | Pages: 52-63

CLINICAL EVALUATION OF THE EFFICIENCY OF ORTHOPEDIC TREATMENT OF PATIENTS WITH EDENTULOUS JAWS WITH COMPLETE REMOVABLE DENTURES USING C-SILICONE MATERIALS FOR FUNCTIONAL IMPRESSIONS
Introduction. Prosthetics of edentulous jaw is one of the most difficult sections of prosthetic dentistry for many years. The difficulty lies in the production of functionally effective complete dentures that are in direct proportion to their fixation on the jaws, stabilization during chewing and even distribution of pressure on the underlying tissues.

The aim of this research was to conduct a comparative clinical evaluation of the efficiency of the complete removable laminar dentures that were made with use of the new materials for functional impressions.

Methods. At...
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2017 year | Issue: 1 | Pages: 37-51

MANAGEMENT MODEL BY MEDICAL PERSONNEL’S MOTIVATION ON THE EXAMPLE OF THE REGIONAL ONCOLOGY CENTER OF SEMEY
Author(s):
The paper presents a model of motivational management by medical staff of Regional oncology center of Semey city, on the basis of which is situated the chair of oncology and radiology named after D.R. Mussinov, MD, professor. At the chair are trained on the residency program, magistracy, Ph doctoral program. Staff motivation is set out in the form of implementation of the Program development of oncological cancer care in 2012-2015 years, including the development of nuclear medicine. Creation of highly efficient and motivated teams, including in health care institutions, will increase labor pr...
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2015 year | Issue: 1 | Pages: 70-76

CONDITION OF COAGULATION HEMOSTASIS AMONG WOMEN, WHO ARE IN THE RISK GROUP BY POSTPARTUM HAEMORRHAGE DEPENDING ON CHILDBIRTHS PARITY
Background: Obstetric haemorrhage is the important issue of obstetrics and one of the major causes of maternal mortality and morbidity in the world. Multiparous women take up a large proportion among dead women. More than 2/3 of blood loss, including threatening the mother’s life, is associated with disorders of hemostasis.
The aim: to evaluate the coagulation system in women with risk factors for postpartum haemorrhage depending on childbirths parity.
Methods: 126 pregnant women were examined, i.e. 96 pregnant women of haemorrhage risk group and 30 pregnant women with physiologic ...
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2015 year | Issue: 1 | Pages: 60-69