LOW KLOTHO LEVELS AND HIGH PLATELET REACTIVITY AS PREDICTORS OF ADVERSE OUTCOMES IN MYOCARDIAL INFARCTION: A CASE-BASED INSIGHT. CLINICAL CASE
We describe a case of ST-elevation myocardial infarction in a 74-year-old patient with peripheral artery disease. Despite dual antiplatelet therapy with high-dose clopidogrel, stent thrombosis and recurrent infarction occurred, requiring escalation to ticagrelor. Additionally, a low level of Klotho protein was detected, associated with increased risk of complications. This case highlights the importance of platelet function testing and emerging biomarkers for individualized therapy.
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Zhunuspekova A.S.,Akkaliyev M.N., Ashirov B.A., Mansurova J.A., Tokbulatova M.О., Kapakova M.A., Toktarova Zh.Zh., Nurgalieva D.T. Low klotho levels and high platelet reactivity as predictors of adverse outcomes in myocardial infarction: a case-based insight Clinical case // Nauka i Zdravookhranenie [Science & Healthcare]. 2025. Vol.27 (5), pp. 267-273. doi 10.34689/SH.2025.27.5.031Related publications:
LOW KLOTHO LEVELS AND HIGH PLATELET REACTIVITY AS PREDICTORS OF ADVERSE OUTCOMES IN MYOCARDIAL INFARCTION: A CASE-BASED INSIGHT. CLINICAL CASE
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