THE IMPACT OF ANTIEPILEPTIC DRUGS ON COGNITIVE FUNCTIONS IN EPILEPSY. LITERATURE REVIEW
Background: Epilepsy affects more than 70 million people worldwide. Antiepileptic drugs (AEDs) represent the basis of treatment; however, 30-40% of patients develop drug resistance. In addition, cognitive impairments are frequently observed in the context of polytherapy.
Objective: To analyze the literature on the effects of antiepileptic drugs on cognitive functions assessed using EpiTrack tool in patients with epilepsy.
Materials and methods: A literature search was performed in PubMed, Scopus, and Google Scholar databases. Eligible studies included full-text publications in English and Russian over the past 15 years that investigated the effect of antiepileptic drugs on cognitive functions.
Results: A total of 1,066 records were identified in the PubMed, Scopus, and Google Scholar databases. After screening, 5 full-text articles met the inclusion criteria and were analyzed.
Conclusions: The review highlights that the cognitive impact of AEDs depends on both the quantity and the pharmacological profile of the drugs used.
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Bekenova N., Kassiyeva B., Aitkaliyev A., Suleimenova A., Vochshenkova T., Dossov M., Zhumabayeva G. The Impact of Antiepileptic Drugs on Cognitive Functions in Epilepsy. Literature review // Nauka i Zdravookhranenie [Science & Healthcare]. 2025. Vol.27 (5), pp. 244-250. doi 10.34689/SH.2025.27.5.028Related publications:
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