Science & Healthcare

Introduction: effective prevention of chronic kidney disease is possible on the basis of early detection of risk factors for its development, elaboration of measures for their stratification, and searching for optimal diagnostic markers.

Aim: determination of risk factors prevalence for progression of chronic kidney disease in patients with chronic glomerulonephritis.

Materials and methods. The design of the study is a cross-sectional sociological study.116 patients undergoing treatment in nephrological department of the Hospital of nephrology, internal and occupational diseases named after EM Tareev, First Moscow State Medical University named after I.M. Sechenov participated in the study of risk factors during 2014.

The criteria for inclusion in the study were diagnosed chronic glomerulonephritis, age 18-70 years. Exclusion criteria: other kidney diseases, age younger than 18 and older than 70 years.

The diagnosis of chronic glomerulonephritis was based on anamnesis of the disease, clinical (renal and extrarenall symptoms), laboratory indicators (urinary syndrome, nitrogen excretion and filtration function of the kidneys, general and biochemical blood tests), as well as results of instrumental studies (ultrasound, including echocardiography).

By analogy with the WHO-recommended STEPS method for determining risk factors for chronic non-infection diseases the study also included series of stages: interviews, anthropometric measurements and biochemical blood counts, the work was complemented by questions about specific risk factors for CKD and a large pool of objective clinical information needed for implementation the next task on risk stratification. It is possible within the framework of a survey of a patient undergoing hospital treatment.

The database was accumulated in the MS Excel program for Windows, statistical processing of the data in the study was carried out using IBM SPSS 21.0, SAS 6.0. Methods for analyzing the results: descriptive analysis.

Results: in the study group it were detected a high proportion of smokers (22.4%; 95% CI: 15.97%, 31.44%), low adherence to regular physical activity (43.1%; 95% CI: 34.97%, 53, 13%), insufficient awareness of the optimal values of blood pressure (23.9%; 95% CI: 15.8%, 36.24%) and the importance of a salt-free diet (57.8%; 95% CI: 49.43%, 67.5% %), as well as low adherence to regular surveys (56.9%; 95% CI: 48.56%, 66.65%).

Conclusion: Analyses of results of interviewing demonstrates existing potential for the implementation of preventive programs aimed at realization of modification the patient's lifestyle and forming a healthy lifestyle in patients with chronic kidney disease.