Science & Healthcare

Background: long-term exposure to ionizing radiation in small doses on the human body is manifested by violations of the adaptive response of regulatory systems to stress.

Aim: to perform a systematic search of valid scientific data in order to assess the disorders of nonspecific resistance in the human organism due to long-term exposure to radiation in small doses

Materials and methods. The search for scientific publications was carried out in the evidence-based medicine’s databases (PubMed, Cochrane Library, ResearchGate, Google Scholar) and in the electronic scientific libraries (CyberLeninka). A total of 312 literary sources were found, 46 articles were selected for further analysis.

Results: the relevant scientific papers found in electronic databases are characterized by the marked heterogeneity. Most of the published studies belong to the category of cross-sectional, we could also find a small amount of cohort studies and unsystematic literature reviews.

Conclusion: Literary sources in the studied field found in various databases allow us to define a certain pattern of development of effects of small doses of radiation to the regulatory systems of the human organism. Studies carried out in Kazakhstan require further development and continuation due to the fact that until now large populations continue to live in ecologically unfavorable territories.