CURRENT STATE OF THE PROBLEM OF RESTENOSIS OF THE CORONARY ARTERIES AFTER ENDOVASCULAR STENTING: REVIEW OF LITERATURE
Introduction: Today percutaneous coronary interventions (PCI) occupy a leading position among invasive methods for treating coronary heart disease (CHD). Despite the constant development of PCI technology, the incidence of restenosis remains at a fairly high level of 15-57%. In this case, as a rule, the substrate of occlusion is not atherosclerosis, but fibrosis, which causes the difficulty of repeated recanalization and a lower percentage of technical success in restoring blood flow. Timely diagnosis with the aim of early detection of restenosis and its correction seems to be an extremely urgent problem for practical health care, which causes scientific and practical interest in this issue and serves as the basis for the present study.
Purpose: to study the current state of the problem of coronary artery restenosis after endovascular stenting according to literature data.
Search strategy: search and analysis of scientific publications in the databases and web resources, such as MEDLINE, Google Scholar, Cyberleninka, Springer Link and eLIBRARY electronic library. The searching period was from 2012 to 2020. Inclusion criteria: reports on randomized and cohort studies conducted on large populations, meta-analyzes and systematic reviews, diagnostic and treatment protocols, articles in English and Russian. Exclusion criteria: personal messages, newspaper publications, abstracts, articles with fuzzy conclusions, as well as articles with paid access. A total of 153 publications were analyzed, 66 of which are included in this review.
Results: To date, many scientific papers have been published aimed at studying the problem of restenosis of coronary arteries. However, in general, the problem of restenosis of coronary arteries remains unresolved, most of the works in this direction are devoted to the choice of the method of revascularization, there is no clear "hierarchy" of risk factors for the development of restenosis after endovascular stenting.
Conclusions: Further scientific developments in this direction will be of particular relevance and will make it possible not only to assess the degree of influence of individual risk factors and their combinations on the development of coronary artery restenosis, but also to develop recommendations for selecting patients with a high risk of restenosis for timely determination of indications for repeated coronarography and revascularization.
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Zemlyanskaya N.S., Derbissalina G.A., Aripov M.A., Zemlyanskiy V.V. Current state of the problem of restenosis of the coronary arteries after endovascular stenting: review of literature // Nauka i Zdravookhranenie [Science & Healthcare]. 2020, (Vol.22) 4, pp. 32-48. doi:10.34689/SH.2020.22.4.004Related publications:
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