DIAGNOSTIC CRITERIA AND TREATMENT OPTIONS FOR ULCERATIVE COLITIS. LITERATURE REVIEW
Relevance. Chronic inflammatory bowel diseases - Ulcerative colitis are among the most severe diseases of the digestive system, and many authors emphasize the prevalence of chronic inflammatory bowel disease among young people of working age, the manifestation of pathology from 30 to 50% of all cases in adolescents; severe progressive course, systemic manifestations, leading to persistent disability and the formation of resistance to treatment at 3-6 years [1-5].
Aim: Review of the current literature on optimizing the diagnosis of ulcerative colitis and the effectiveness of biological therapy.
Research strategy: The search and analysis of the material for writing articles were carried out on the information bases and web sites PubMed, Scopus, Medline, Web of Science, SpringerLink, Medicine, cyberleninka.ru. The depth of the search included data from the last 10 years. Out of more than 90 literary sources, 66 were selected as analytical material for this article. Inclusion criteria: publications in Kazakh, Russian and English, full-text epidemiological and clinical studies conference proceedings. Exclusion criteria: recurring publications.
Results: According to the results of the literature review, there are no reliable epidemiological data on inflammatory diseases of the intestinal mucosa. The authors note the low efficiency of traditional pathogenetic therapy and the high efficiency of genetically engineered biological therapy.
Conclusions: Application and continuation of programmed genetic engineering biological therapy for chronic inflammatory bowel diseases from 3 to 6 months, ultimately leading to the induction of remission and improving the quality of life of patients with chronic inflammatory bowel diseases.
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Kalimoldina G.K., Zhumadilova Z.K., Kaskabayeva A.Sh., Muzdubaeva Zh.Ye., Raisova K.K. Diagnostic criteria and treatment options for ulcerative colitis. Literature review // Nauka i Zdravookhranenie [Science & Healthcare]. 2021, (Vol.23) 2, pp. 66-80. doi:10.34689/SH.2021.23.2.007Related publications:
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