Online ISSN: 3007-0244,
Print ISSN:  2410-4280
THE CLINICAL PICTURE OF COVID-19 IN ADULT PATIENTS OF THE TURKESTAN REGION, DEPENDING ON COMORBID DISEASES
Currently, the new coronavirus infection and its consequences, despite significant progress in vaccination and treatment, does not lose relevance. The purpose of the study: To conduct a comparative analysis of symptoms depending on the presence of comorbid diseases in patients with COVID-19 hospitalized in infectious hospitals of the Turkestan region. Research methods: A retrospective observational study was conducted, during which we analyzed the data of patients with COVID-19 hospitalized in infectious diseases hospitals of the Turkestan region in 2020-2021. The data of 958 patients with COVID-19 were randomly selected from the information system, information about the clinical symptoms of COVID-19 and comorbidities were extracted from medical records. The collected data were entered into the trial version of the SPSS program (SPSS 20 Inc, Chicago, IL, USA), p < 0,05 was considered as significance threshold. Results: In the studied sample of patients with COVID-19, the most common comorbidities were diseases of the respiratory system - 45.6%, in second place were cardiovascular diseases - 36.2%. The most frequent symptoms upon admission were cough - 68.8%, fever - 56.7%, and shortness of breath - 47.4%. Less frequent symptoms were diarrhea -3%, dizziness - 29%, vomiting - 12.5%, myalgia - 19.1%. The data obtained by us indicate that in COVID-19 patients with comorbid diseases of the cardiovascular system, respiratory organs, nervous system and diabetes mellitus, such clinical symptoms as cough over 80.0%, diarrhea over 7.0%, dizziness above 41.0%, myalgia – above 27.0%, shortness of breath above 64.0 % and fever over 71.0 % were statistically significantly more common. Conclusions: In the older age group, clinical symptoms were significantly more common. In general, in the presence of comorbid pathology, almost all the symptoms were observed much more often, which indicates a more severe clinical course COVID-19 in this category of patients.
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Category of articles: COVID-19 - Topical Subject

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Sadykova K.Zh., Nuskabayeva G.O., Madenbay K.M., Kulakhmetova Kh.B., Aidarbekova D.N., Azizhodzhayeva D.Sh., Kemelbekov K.S., Mussina А.А. The clinical picture of COVID-19 in adult patients of the Turkestan region, depending on comorbid diseases // Nauka i Zdravookhranenie [Science & Healthcare]. 2023, (Vol.25) 5, pp. 17-26. doi 10.34689/SH.2023.25.5.002

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