QUANTITATIVE AND QUALITATIVE CHEMICAL ANALYSIS OF SMOKELESS TOBACCO NASVAY
Introduction. Nasvay is one of the smokeless tobacco, which is very popular in Central Asia. Sublingual use of which reinforces the effect of the toxic ingredients, primarily on the heart, blood vessels, the nervous system, and then accelerates addictive.
The purpose of the study. To conduct a quantitative and qualitative chemical compositional analysis of a smoke-free tobacco nasvay, one kind of a smokeless tobacco and to compare it with GOTHIATEK standard.
Materials and methods. The study of the chemical composition nasvay one of the types of smokeless tobacco was held at the Laboratory Research & Development, Chemical Analysis, Swedish Match Scandinavia Division SE-118 85 Stockholm Sweden. Nasvay had been bought on the market of Karaganda. Multiple and batch method of analysis of pesticides in tobacco and tobacco products has been conducted. Theoretical probability of the occurrence of substances concentration in the compared specimen with GOTHIATEK standard has been researched through z-test. Critical level of distinction has been revealed on the level no less than (<) 0,05. The calculation has been conducted in SAS software.
Results. In the study we found no pesticide residues. Bacterial inoculation showed us the high dissemination of bacteria in two batches of nasvay that indicates a lack of sterile (clean) conditions during manufacture, transport and storage nasvay. In tobacco nasvay we found a large number of nitrite ions in comparison with indicators of the standard GOTHIATEK. Level of Tobacco-specific N-nitrosamines (TSNA) was either just above or consistent with GOTHIATEK, like Swedish snus, which indicators are within the normal standard GOTHIATEK. In the study of different samples of impurities nasvai, we found the same elements, such as benzo (a) pyrene, chromium, nickel, cadmium, lead and arsenic. This suggests that they were made in one way. But due to the fact that the amount of these elements between samples differs dramatically from one another, this means that the production of nasvai occurred with handicraft methods and ingredients for its production were added without accurate accounting. The number of chromium, nickel, cadmium, lead and arsenic are overstated of standard GOTHIATEK.
Conclusions. Nasvay is dangerous to human; according to literature data the revealed by us components have toxic or carcinogenic activity.
Meiram U. Raganin1, http://orcid.org/0000-0001-8271-3060
Ulf Zätterström2,
Johan Lindholm3
1 Dental Clinic "SPS", Astana, Kazakhstan;
2 Clinic Aleris AB, Stockholm, Sweden;
3 Laboratory Research & Development, Chemical Analysis,
Swedish Match Scandinavia Division SE-118 85, Stockholm, Sweden.
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