FACTORS, ASSOCIATED WITH ONE YEAR SURVIVAL AFTER STROKE IN KAZAKHSTAN: A COHORT STUDY
Introduction. Many unresolved question exist about the predictors of stroke outcome. The evidence on the determinants of stroke survival in Kazakhstan is very scarce, despite the high prevalence of the problem.
The aim: To study factors associated with one -year stroke survival in a population of Semey, Kazakhstan.
Methods. All cases of stroke were included in a cohort in Semey from 01.01.2014 to 31.12.15 (N = 937).Survival of patients with stroke was assessed using Kaplan-Mayer curves and log-rank tests. Independent associations of the studied factors with survival were studied using multivariable Cox proportional hazard analysis. Crude and adjusted hazard ratios (RR) were calculated with 95% confidence intervals (CI).
Results. Annual 12-years survival was 67.7% (95% CI: 64,6-70,6) in the study population. Age over 70 years (RR= 1,87; 95% CI: 1,09-3,20),Russian ethnicity (RR=1,69;95% CI 1,31-2,17), hemorrhagic and subarachnoid hemorrhage (RR=3,06;95% CI 2,32-4,05) and (RR=3,72;95% CI 1,97-7,01) respectively, history of myocardial infarction (RR=1,41;95% CI 1,03-1,94),а high NIHSS score with 12-months survival.
Conclusions: Factors influencing survival of patients after stroke in Kazakhstan were identified. Our results may be used for the development of therapeutic and rehabilitation measures to improve long-term survival after stroke
Asel K. Akimzhanova 1, http://orcid.org/0000-0003-3248-575
Andrej M. Grjibovski 2-5, http://orcid.org/0000-0002-5464-0498
Talgat N. Khaibullin 1, http://orcid.org/0000-0003-1886-0538
Olga P. Patrusheva 6,
Kuat D. Akimzhanov1, http://orcid.org/0000-0002-8608-0771
1 Semey State Medical University, Semey, Kazakhstan;
2 Norwegian Institute of Public Health, Oslo, Norway;
3 Northern State Medical University, Arkhangelsk, Russia;
4 International Kazakh-Turkish University, Turkestan, Kazakhstan;
5 North-Eastern Federal University, Yakutsk, Russia;
6 Arkhangelsk Regional Hospital, Arkhangelsk, Russia
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13. Cabral N.L., Muller M., Franco S.C., Longo A., Moro C., Nagel V. et al. Three-year survival and recurrence after first-ever stroke: the Joinville stroke registry. BMC Neurology. 2015, 15, pp. 1-7.
14. Goff D.C., Lloyd-Jones D.M., Bennett G., et al. 2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2014, 63, pp. 2935–2959.
15. Correia M., Magalhães R., Rui Silva M., et al. Stroke Types in Rural and Urban Northern Portugal: Incidence and 7-Year Survival in a Community-Based Study. Cerebrovasc Dis. 2013, 3, pp. 137–149.
16. Feigin V.L., Forouzanfar M.H., Krishnamurthi R.Global and regional burden of stroke during 1990-2010: findings from the Global Burden of Disease Study 2010. Lancet. 2014. 18. (383), pp. 245-54.
17. Flegal K. M., Kit B.K., Orpana H. Graubard B.I. Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis. JAMA. 2013, 309, рр. 71–82.
18. Gustavo S.; Hill M.D.; O’Donnell M.; et al. Variables associated with 7-day, 30-day, and 1-year fatality after ischemic stroke. Stroke. 2008, pp. 2319-2323.
19. Huhley R.R., Hirakashha Y., Hussain M.A., et al. Age- and Seh-Specific Burden of Cardiovascular Disease Attributable to 5 Major and Modifiable Risk Factors in 10 Asian Countries of the Shhestern Pacific Region. Circ J. 2015, 79 (8), pp. 1662-74.
20. Kulesh S.D.; Kastsinevich T.M., Kliatskova L.A., et al. Long-Term outcome after stroke in Belarus. The Grodno stroke study. Stroke. 2011, 28 (7), pp. 3274-3276.
21. Palm F., Urbanek. S., Rose S., et al. Stroke incidence and survival in Ludshhigshafen am Rhim, Germany: the Ludshhigshafen stroke study. Stroke.2010, 41, pp. 1865-1870.
22. Sanja Medic, Beslac-Bumbasirevic L, Kisic-Tepavcevic D., Pekmezovicc T. Short-Term and Long-Term Stroke Survival: The Belgrade Prognostic Study. J Clin Neurol. 2013, 9, pp. 14-20.
23. Sun Y., Lee S.H., Heng B.H., Chin V.S. 5-year survival and rehospitalization due to stroke recurrence among patients with hemorrhagic or ischemic strokes in Singapore. BMC Neurol. 2013, 13, pp. 133-141.
24. Wilson P.W., D'Agostino R.B., Sullivan L., Parise H., Kannel W.B. Overweight and obesity as determinants of cardiovascular risk: the Framingham experience. Arch Intern Med. 2002, 9. 162, рр. 1867-72.
25. Walker R.W., Jusabani A., Aris E., Gray W.K., et al. Stroke risk factors in an incident population in urban and rural Tanzania: a prospective, community-based, case-control study. Lancet Glob Health. 2013, 1, pp. 282-288.
26. Wolf P.A., Abbott R. D. and Kannel W. B. Atrial fibrillation as an independent risk factor fоr stroke: the Framingham Study. Stroke. 1991, 22, pp. 983-988.
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Акимжанова А.К., Гржибовский A.М., Хайбуллин Т.Н., Патрушева О.П., Акимжанов К.Д. Факторы, влияющие на однолетнюю выживаемость пациентов после инсульта в Казахстане: когортное исследование / / Наука и Здравоохранение. 2016. №3. С. 46-57. Akimzhanova A.K., Grjibovski A.M., Khaibullin T.N., Patrusheva O.P., Akimzhanov K.D. Factors, associated with one year survival after stroke in Kazakhstan: a cohort study. Nauka i Zdravookhranenie [Science & Healthcare]. 2016, 3, pp. 46-57. Әкімжанова Ә.Қ., Гржибовский A.М., Хайбуллин Т.Н., Патрушева О.П., Әкімжанов Қ.Д. Қазақстанда инсультан кейінгі науқастардың біржылдық өмір сүруіне əсер ететін факторлар: когортты зерттеу / / Ғылым және Денсаулық сақтау. 2016. №3. Б. 46-57.Related publications:
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