ANALYSIS OF RELATIONSHIPS / DEPENDENCIES OF GENERAL CONDITION DURING ADMISSION AND OUTCOMES OF DISEASE IN PATIENTS WITH BRAIN TUMORS
Introduction. Brain tumors, despite advances in the diagnosis and treatment of tumors in general, are an urgent problem due to low patient survival and high disability.
Purpose of the study. The purpose of this study: to study the relationship / dependence of the outcome of surgical treatment of neurooncological patients on the characteristics of the clinical manifestations of the disease and some organizational aspects.
Methods. The study is an observational, descriptive and analytical, conducted in 2017-2018. 636 medical records of an inpatient (in Semey and in Ust-Kamenogorsk) for the period 2012-2017 were studied using the method of continuous observation.
The dependence of the general somatic status and outcome of the disease on the characteristics of the clinical manifestations of the disease and some organizational aspects was studied based on the materials of forms 003 / y (inpatient medical record) of the University Hospital of the State Medical University of Semey and Ust-Kamenogorsk city hospital №1.
Communication / dependency assessment was performed using correlation analysis (Spearman's rank correlation coefficient).
Results. The results indicate the relationship / dependence of the state upon admission of neuro-oncological patients and the outcome of the disease on age and social status, place of residence, presence of neurological deficit and tumor localization, type of hospitalization, who referred the patient and after what time from the onset of the disease the patient was hospitalized, complications of the operation and being in intensive care.
Findings. The condition of admission of neuro-oncological patients and the outcome of the disease depend on the personal data of the patients, tumor characteristics, neurological deficit and organizational aspects of medical care.
Zhandos T. Uap, https://orcid.org/0000-0003-2572-8201
Tolkyn A. Bulegenov,
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5. Barnholtz-Sloan J.S., et al. Epidemiology of Brain Tumors. Neurol Clin. 2018. №36(3). R.395-419.
6. Baldin E., et al. Incidence of neuroepithelial primary brain tumors among adult population of Emilia-Romagna Region, Italy. Neurol Sci. 2017. №38(2). R.255-262.
7. Donoho D.A., et al. Predictors of 30- and 90-day readmission following craniotomy for malignant brain tumors: analysis of nationwide data. J Neurooncol. 2018. №136(1). R.87-94.
8. Darlix A. et al. Epidemiology for primary brain tumors: a nationwide population-based study. J Neurooncol. 2017. №131(3). R.525-546.
9. de Robles P., et al. The worldwide incidence and prevalence of primary brain tumors: a systematic review and meta-analysis. Neuro Oncol. 2015. №17(6). R.776-83.
10. Fox BD., et al. Epidemiology of metastatic brain tumors. Neurosurg Clin N Am. 2011. №22(1). R.1-6.
11. Hjern A., Disability in adult survivors of childhood cancer: a Swedish national cohort study. J Clin Oncol. 2007. №20;25(33). R.5262-6.
12. Johnson KJ., et al. Brain tumor epidemiology in the era of precision medicine: The 2017 Brain Tumor Epidemiology Consortium meeting report. Clin Neuropathol. 2017. №36(6). R.255-263.
13. Leece R., et al. Global incidence of malignant brain and other central nervous system tumors by histology, 2003-2007. Neuro Oncol. 2017. №19;19(11). R.1553-1564.
14. Lin YJ., et al. Trends in the incidence of primary malignant brain tumors in Taiwan and correlation with comorbidities: A population-based study, Clin Neurol Neurosurg. 2017. №159. R.72-82.
15. Madhavan R., et al. Pediatric brain tumors: An analysis of 5 years of data from a tertiary cancer care center, India, Indian J Cancer. 2016. №53(4). R.562-565.
16. Piñeros M., et al. Descriptive epidemiology of brain and central nervous system cancers in Central and South America. Cancer Epidemiol. 2016. №44. R.141-149.
17. Philips A., Brain Tumours: Rise in Glioblastoma Multiforme Incidence in England 1995-2015 Suggests an Adverse Environmental or Lifestyle Factor. J Environ Public Health. 2018. №24.
18. Shirazi N., et al. Profile of Primary Pediatric Brain and Spinal Cord Tumors from North India. Indian J Med Paediatr Oncol. 2017. №38(1). R.10-14.
19. Vatner RE., et al. Endocrine Deficiency as a Function of Radiation Dose to the Hypothalamus and Pituitary in Pediatric and Young Adult Patients With Brain Tumors. J Clin Oncol. 2018. №17.
20. Zhang AS., et al. Complete prevalence of malignant primary brain tumors registry data in the United States compared with other common cancers, 2010. Neuro Oncol. 2017. №1;19(5). R.726-735.
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Uap Zh.T., Bulegenov T.A. Analysis of relationships / dependencies of general condition during admission and outcomes of disease in patients with brain tumors // Nauka i Zdravookhranenie [Science & Healthcare]. 2019, (Vol.21) 3, pp. 92-98.Related publications:
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