THE INDICATOR OF THE VACCINATION STATUS AND THE INCIDENCE OF MEASLES IN THE REPUBLIC OF KAZAKHSTAN
Measles is a highly contagious (95-96%) viral, potentially eliminated disease, since the reservoir is exclusively human. To date, safe, effective vaccines have been developed and are widely used, as well as sensitive and specific diagnostic tests. It should be noted that in many countries, the measles vaccine is included in the immunization program of the population and is freely available.
The purpose of the study: To study the incidence of measles in children aged 0 to 14 years in the Republic of Kazakhstan, as well as their vaccination status.
Materials and methods: The retrospective epidemiological analysis of the incidence of measles and the vaccination status of children aged 0 to 14 years was carried out for the period from November 1, 2018 to December 30, 2019, according to the data of the Public Health Protection Committee of the Republic of Kazakhstan and the data of the Sanitary and Epidemiological Control Committee of the Ministry of Health of the Republic of Kazakhstan.
The statistical analysis was carried out in the programs R statistics (V. 4) under the following conditions: quantitative data with an abnormal distribution: nonparametric Kruskal-Wallis criterion for independent groups.
Results and conclusions: The analysis of the incidence of measles among the population showed an increase in the incidence of measles, which amounted to 13,873 cases, of which 73% (n=10189) were children under 14 years of age. The vast majority of outbreaks of this disease are associated with limited coverage of the population in vaccination programs. This study revealed a low vaccination coverage of children under 1 year of 50.2% (n=4098), from 1 year to 14 years of 49.8% (n=4072), which is associated with various reasons (not reaching age, medical withdrawal, refusal of parents from vaccination). To date, it has been proven that the most reliable means of preventing measles is vaccination of the population. The world experience in eliminating measles among the population recommends universal immunization of children and vaccination of all susceptible people with measles vaccine.
Aigerim A. Zhuzzhasarova 1,2, https://orcid.org/0000-0001-6556-4489
Dinagul A. Baesheva 1,2, https://orcid.org/0000-0001-6843-9712
Bayan R. Turdalina 1,2, https://orcid.org/0000-0001-5672-7370
Aliya Zh. Seidullaeva 1,2, https://orcid.org/0000-0002-0073-4405
Alyona V. Altynbekova 1,2, https://orcid.org/0000-0002-4407-4525
Aylkyn Mynzhanova 1,2, https://orcid.org/0000-0002-3015-4153
Almagul R. Kushugulova 3, https://orcid.org/0000-0001-9479-0899
1 NCS "Medical University Astana", Nur-Sultan, Republic of Kazakhstan;
2 Multidisciplinary City Children's Hospital №3, Nur-Sultan, Republic of Kazakhstan;
3 National Laboratory Astana, Nazarbayev University, Nur-Sultan, Republic of Kazakhstan.
1. Мазанкова Л.Н., Нестерина Л.Ф., Горбунов С.Г. Корь у детей. Российски вестник перинатологии и педиатрии, 3, 2012. 49-55.
2. Abeev A., Zhylkibayev A., Kamalova D., Kusheva N., Nusupbaeva G., Tleumbetova N., Smagul M., Beissenova S., Aubakirova S., Kassenova Z., Demessinova B., Amanbayev A., Ramankulov Y., Shevtsov A. Epidemiological Outbreaks of Measles Virus in Kazakhstan during 2015 // Japanese journal of infectious diseases, 2018. 71(5), 354–359. doi.org/10.7883/yoken.JJID.2017.565
3. Angelo K.M., Gastañaduy P.A., Walker A.T., Patel M., Reef S., Lee C.V., Nemhauser J. Spread of Measles in Europe and Implications for US Travelers // Pediatrics, 2019. 144(1), e20190414. doi.org/10.1542/peds.2019-0414
4. Centers for Disease Control and Prevention. Measles cases and outbreaks. Measles cases in 2019. Available at: https://www.cdc.gov/measles/cases-outbreaks.html. Available: 03.05.2019.
5. Dascalu S. Measles Epidemics in Romania: Lessons for Public Health and Future Policy. Frontiers in public health, 2019. 7, 98. doi.org/10.3389/fpubh.2019.00098
6. De Serres G., Boulianne N., Defay F., Brousseau N., Benoît M., Lacoursière S., Guillemette F., Soto J., Ouakki M., Ward B.J., Skowronski D.M. Higher risk of measles when the first dose of a 2-dose schedule of measles vaccine is given at 12-14 months versus 15 months of age // Clinical infectious diseases: an official publication of the Infectious Diseases Society of America, (2012). 55(3), 394–402. doi.org/10.1093/cid/cis439
7. European Centre for Disease Prevention and Control. Measles outbreaks still ongoing in 2018 and deaths reported from four countries. 2018. https://www.ecdc.europa.eu/en/news-events/measles-outbreaks-still-ongoing-2018-and-fatalities-reported-four-countries. Avalable: 09.11.2019.
8. Griffin D.E. Measles Vaccine // Viral immunology, (2018). 31(2), 86–95. doi.org/10.1089/vim.2017.0143
9. Hull B., Hendry A., Dey A., Beard F., Brotherton J., McIntyre P. Annual Immunisation Coverage Report 2016 // Communicable diseases intelligence, 2019.43, 10.33321/cdi.2019.43.44. doi.org/10.33321/cdi.2019.43.44
10. Kondova I.T., Milenkovic Z., Marinkovic S.P., Bosevska G., Kuzmanovska G., Kondov G., Alabakovska S., Muller C.P., Hübschen J.M. Measles outbreak in Macedonia: epidemiological, clinical and laboratory findings and identification of susceptible cohorts. PloS one, 2013. 8(9), e74754. doi.org/10.1371/journal.pone.0074754
11. Kumar D., Sabella C. Measles: Back again. Cleveland Clinic journal of medicine, 2016.83(5), 340–344. doi.org/10.3949/ccjm.83a.15039
12. Leung A.K., Hon K.L., Leong K.F., Sergi C.M. Measles: a disease often forgotten but not gone // Hong Kong medical journal = Xianggang yi xue za zhi, 2018.24(5), 512–520. doi.org/10.12809/hkmj187470
13. Martins C., Garly M.L., Bale C., Rodrigues A., Benn C.S., Whittle H., Aaby P. Measles antibody levels after vaccination with Edmonston-Zagreb and Schwarz measles vaccine at 9 months or at 9 and 18 months of age: a serological study within a randomised trial of different measles vaccines // Vaccine, 2013.31(48), 5766–5771. doi.org/10.1016/j.vaccine.2013.08.044
14. Measles vaccines: WHO position paper. Releve epidemiologique hebdomadaire, 2009. 84(35), 349–360.
15. Mina M.J. Measles, immune suppression and vaccination: direct and indirect nonspecific vaccine benefits // The Journal of infection, 2017. 74 Suppl 1, S10–S17. doi.org/10.1016/S0163-4453(17)30185-8
16. Moss W.J. Measles // Lancet (London, England), 2017. 390(10111), 2490–2502. doi.org/10.1016/S0140-6736(17)31463-0
17. Ristić M., Milošević V., Medić S., Djekić Malbaša J., Rajčević S., Boban J., Petrović V. Sero-epidemiological study in prediction of the risk groups for measles outbreaks in Vojvodina, Serbia. PloS one. 2019, 14(5), e0216219. doi.org/10.1371/journal.pone.0216219
18. Roberts L. Is measles next? // Science (New York, N.Y.), 2015. 348(6238), 958–963. doi.org/10.1126/science.348.6238.958
19. Storr C., Sanftenberg L., Schelling J., Heininger U., Schneider A. Measles Status-Barriers to Vaccination and Strategies for Overcoming Them // Deutsches Arzteblatt international, 2018. 15(43), 723–730. doi.org/10.3238/arztebl.2018.0723
20. Tomljenovic M., Lakic M., Vilibic-Cavlek T., Kurecic Filipovic S., Visekruna Vucina V., Babic-Erceg A., Ljubic M., Pem Novosel I., Ilic M., Tabain I., Ivancic-Jelecki J., Hansen L., Kaic B. Measles outbreak in Dubrovnik-Neretva County, Croatia, May to June 2018 // Euro surveillance: bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2020. 25(7), 1900434. doi.org/10.2807/1560-7917.ES.2020.25.7.1900434
21. Turner R., PLOS Medicine Editors Measles vaccination: A matter of confidence and commitment // PLoS medicine, 2019. 16(3), e1002770. https://doi.org/10.1371/journal.pmed.1002770 Available: 14.02.2021.
22. Uzicanin A., Zimmerman L. Field effectiveness of live attenuated measles-containing vaccines: a review of published literature // The Journal of infectious diseases, 2011. 204 Suppl 1, S133–S148. doi.org/10.1093/infdis/jir102
23. Palamara M.A. et al. Measles outbreak from February to August 2017 in Messina, Italy. Journal of preventive medicine and hygiene. vol. 59,1 E8-E13. 30 Mar. 2018, doi:10.15167/2421-4248/jpmh2018.59.1.853World Health Organization. Measles cases hit record high in the European Region. 2018.
24. WHO. Pan American Health Organization: The Americas region is declared measles free. Available 24.08.2018.
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Zhuzzhasarova A.A., Baesheva D.A., Turdalina B.R., Seidullaeva A.Zh., Altynbekova A.V., Mynzhanova A., Kushugulova A.R. The indicator of the vaccination status and the incidence of measles in the Republic of Kazakhstan // Nauka i Zdravookhranenie [Science & Healthcare]. 2021, (Vol.23) 4, pp. 155-162. doi 10.34689/SH.2021.23.4.017Related publications:
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