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DETECTION OF MUTATIONS IN RPOB GENE RESPONSIBLE FOR RIFAMPICIN-RESISTANCE AMONG CLINICAL ISOLATES OF M. TUBERCULOSIS FROM DIFFERENT REGIONS OF KAZAKHSTAN
Spectrum of mutations in rpoB gene that cause resistance to one of the main antituberculosis drugs – rifampicin in clinical isolates of M. tuberculosis distributed in 3 regions (Almaty, Kostanay, Kyzylorda) of Kazakhstan was estimated in this study. High frequency of mutation at codon Ser531 of rpoB gene (79,2%) responsible for drug resistance to rifampicin was determined among M. tuberculosis population circulating in the mentioned regions.
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2014 year | Issue: 4 | Pages: 26-27
RISK FACTORS FOR CERVICAL CANCER IN SEMEY REGION
Background: The aim of investigation was to study the main risk factors for cervical cancer in Semey region.
Method: case-control study.
Conclusions. Risk factor for cervical cancer in Semey region for women with uncompleted and secondary school educa-tion is higher than for women with high school education. Also the main risk factors for cervical cancer in study region were the time of starting of menstrual periods, abortion, erosion of cervix, and kind of contraception.
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Method: case-control study.
Conclusions. Risk factor for cervical cancer in Semey region for women with uncompleted and secondary school educa-tion is higher than for women with high school education. Also the main risk factors for cervical cancer in study region were the time of starting of menstrual periods, abortion, erosion of cervix, and kind of contraception.
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2014 year | Issue: 4 | Pages: 23-25
ANALYSIS OF TRENDS IN THE INCIDENCE OF HOSPITALIZED ACUTE MYOCARDIAL INFARCTION IN SEMEY REGION
This study attempted to investigate the incidence of hospitalized acute myocardial infarction (AMI) in Semey region. Using the №14 “Report on contingent of patients discharged from hospital” and №30 “Report of medical organization” data, we investigated trends in the incidence of AMI during 2008 to 2012. In conclusion, the incidence and lethality rates of hospitalized AMI had decreased, and the average rates of decline were Т= – 5.43% and Т= – 3.15%, respectively.
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2014 year | Issue: 4 | Pages: 17-23
INDICATORS OF DAILY MONITORING OF THE BLOOD PRESSURE IN CHILDREN WITH ARTERIAL HYPERTENSION BORN FROM IRRADIATED PARENTS
Daily monitoring of blood pressure (DMBP) was conducted on 48 children with arterial hypertension (AH) and without AH. On the basis of DMBP the groups of children with a stable and labile AH options were selected. According to the studies’ results, it is observed that the absolute majority of children (62.9% of boys and 61.4% of girls) without AH has nighttime blood pressure reduction from 10 to 20%, whereas among patients with AH predominant number of patients has minor nighttime blood pressure reduction; moreover, nighttime increase of blood pressure is ob...
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2014 year | Issue: 4 | Pages: 13-16
SEVERE EXACERBATION OF ASTHMA. DIAGNOSIS, TREATMENT
The exacerbation of bronchial asthma (BA) - is a progressive increase in episodes of coughing, shortness of breath, the appearance of wheezing, breathlessness, feeling short of breath, or various combinations of these symptoms [7,11].
Treatment of acute asthma depends on the patient, experience of medical personnel, on the most effective treatment for each individual patient, the availability of drugs and the availability of equipment for emergency care [15,22].
Mainstay of treatment for acute asthma are multiple appointment of fast inhaled b2-agonist or a combination of ... More
Treatment of acute asthma depends on the patient, experience of medical personnel, on the most effective treatment for each individual patient, the availability of drugs and the availability of equipment for emergency care [15,22].
Mainstay of treatment for acute asthma are multiple appointment of fast inhaled b2-agonist or a combination of ... More
2014 year | Issue: 4 | Pages: 9-12