Online ISSN: 3007-0244,
Print ISSN:  2410-4280
MICROBIOLOGICAL INDICATORS OF OUTPATIENTS’ UNCOMPLICATED URINARY TRACT INFECTION
Introduction: Urinary tract infections are among the most common infections diagnosed in both outpatient and hospitalized patients, but the study of the bacterial structure and resistance of pathogens is not so widely studied at the outpatient stage. We aimed to study microbiologic landscape and antibiotic susceptibility of strains isolated from outpatient’s urine samples. Materials and methods: A prospective microbiological study of bacterial landscape and antibiotic susceptibility of strains isolated from 202 outpatients’ urine samples based on Microbiology Laboratory of National Scientific Medical Research Center during September 2019 to October 2020. Identification of isolates were performed by Vitek-2 automated system. Statistical processing of the obtained data was carried out using Microsoft Excel, the average value, the error of the mean were determined, dynamic changes were determined by the method of linear regression. Differences in mean values were considered statistically significant at p<0.05 Results: During study period, 158 clinical samples were included, 75 strains were isolated; of them and the most frequently isolated microorganisms was E.coli - 76%. Antibiotic susceptibility of E.coli strains was to ampicillin – 43.8%, to III generation cephalosporins – 66.6%, to quinolones – 68.4% and to aminoglycosides – 77.1%. The highest sensitivity is observed to nitrofurantoin 94.7% and co-trimoxazole 89.4%. Conclusion: Based on our results the most frequently pathogens of outpatients’ uncomplicated urinary tract infection was E.coli with high level of susceptibility to nitrofurantoin 94.7% and co-trimoxazole 89.4%.
Nelya M. Bissenova1, http://orcid.org/0000-0001-8722-0398 Elmira А. Tuleubyeva1, Yekaterina V. Trofimchuk1, Aigerim S. Yergаliyevа1, http://orcid.org/0000-0003-2111-9888 Dmitryi A. Kim2, Erkebulan M. Ermaganbetov1 1 National Scientific Medical Research Center, Nur-Sultan c., Republic of Kazakhstan; 2 Municipal Policlinic №7, Nur-Sultan c., Republic of Kazakhstan.
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Bissenova N.M., Tuleubyeva E.А., Trofimchuk Ye.V., Yergаliyevа A.S., Kim D.A., Ermaganbetov E.M. Microbiological indicators of outpatients’ uncomplicated urinary tract infection // Nauka i Zdravookhranenie [Science & Healthcare]. 2022, (Vol.24) 1, pp. 47-53. doi 10.34689/SH.2022.21.1.006

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