GEOGRAPHICAL VARIABILITY OF CORPUS UTERI CANCER INCIDENCE IN KAZAKHSTAN
Introduction: Kazakhstan belongs to the countries with a high incidence and mortality from corpus uteri cancer (CUC). According to the level of morbidity, standardized by age, it is among the 10 most common types of malignant neoplasms. And in the structure of morbidity among women, CUC occupies the 5th place (6.3%).
Aim: To study the epidemiological features of the incidence of uterine body cancer and its spatial and temporal assessment in Kazakhstan.
Materials and methods. A retrospective study was conducted for the period 2009-2018. Descriptive and analytical methods of epidemiology were used. Crude, age-standardized, equalized incidence rates and approximations were calculated. The cartogram compilation method based on the determination of the standard deviation (σ) from the mean value (x) was applied.
Results. During the study period, 10,522 new cases of CUC were registered. The average annual age-standardized incidence rate was 11.1±0.2 cases per 100,000 female population (T=+0.6%; R2=0.083). When compiling cartograms, incidence rates were determined on the basis of standardized indicators: low – up to 8.9, average – from 8.9 to 12.6, high – above 12.6 per 100,000 female population. The results of the spatial analysis showed regions with a higher incidence of CUC per 100,000 female population: Pavlodar, Kostanay, Karaganda, Almaty, Northern Kazakhstan and Astana.
Conclusions. In recent years, the incidence of CUC in Kazakhstan has been growing. High incidence rates were found in the northern regions of the country, and the trend of increasing incidence was more pronounced in the western and eastern regions.
Zhansaya B. Telmanova1-3, https://orcid.org/0000-0002-2364-6520
Aida Zh. Baybusunova1-3, https://orcid.org/0000-0002-4460-0476
Gulnur S. Igissinova4,1, https://orcid.org/0000-0001-6881-2257
Zarina A. Bilyalova1, https://orcid.org/0000-0002-0066-235X
Zhanar Zh. Kozhakhmetova1,2, https://orcid.org/0000-0002-7255-0955
Zhanerke R. Azhetova1,2, https://orcid.org/0000-0002-8266-1720
Serikbay T. Orozbaev2, https://orcid.org/0000-0003-3895-0426
Kuanish T. Kulayev5, https://orcid.org/0000-0002-3886-7238
Yerlan K. Kuandykov5, https://orcid.org/0000-0002-7966-1471
Nurbek S. Igissin1-3, https://orcid.org/0000-0002-2517-6315
1 Central Asian Institute for Medical Research, Astana, the Republic of Kazakhstan;
2 Astana Medical University, Astana, the Republic of Kazakhstan;
3 Eurasian Institute for Cancer Research, Bishkek, the Kyrgyz Republic;
4 Asfendiyarov Kazakh National Medical University, Almaty, the Republic of Kazakhstan;
5 Khoja Akhmet Yassawi International Kazakh-Turkish University, Shymkent, the Republic of Kazakhstan.
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Telmanova Zh.B., Baybusunova A.Zh., Igissinova G.S., Bilyalova Z.A., Kozhakhmetova Zh.Zh., Azhetova Zh.R., Orozbaev S.T., Kulayev K.T., Kuandykov Y.K., Igissin N.S. Geographical variability of corpus uteri cancer incidence in Kazakhstan // Nauka i Zdravookhranenie [Science & Healthcare]. 2023, (Vol.25) 1, pp. 115-122. doi 10.34689/SH.2023.25.1.015Related publications:
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