BREAST CANCER EPIDEMIOLOGY IN KAZAKHSTAN FOR THE PERIOD 2012-2021
Background: Breast cancer (BC) is the most frequent cancer diagnosed in women worldwide, including Kazakhstan. Over the last decade, many factors influenced changes in the epidemiological indicators of BC in in Kazakhstan. This study aimed to explore the epidemiological data of BC from 2012 to 2021 in Kazakhstan.
Materials and methods: Official statistics on BC were studied for the period 2012-2021 (“Report on patients with malignant diseases”, statistical data of the Committee on Statistics of the Ministry of National Economy of the Republic of Kazakhstan). Prevalence, incidence and mortality rates, average growth incidence and mortality rates, the proportion of BC cases detected in the early stage (I) were analyzed retrospectively.
Results: The crude incidence rate (CIR) and age-standardized incidence rate (ASIR) of BC were 48.2 and 44.4 per 100,000 female population respectively. The crude mortality rate (CMR) from BC was 13.9 (95% CI 12.7-15.1) in study period, the age-standardized mortality rate (ASMR) from 2017 to 2021 was 11.2 (95% CI 10.1-12.3).
The highest incidence and mortality rates of BC per 100,000 population were in Pavlodar region (39.2±1.8 and 10.7±0.9). The lowest rates of incidence and mortality of BC were amounted in Turkestan region (11.0±1.1 and 3.5±0.06). The mortality incidence coefficient was 0.28 average and varied by region from 0.21 (Karaganda region) to 0.41 (Zhambyl region). From 2017 to 2021 the proportion of patients diagnosed with BC in stage I was 28.8% and in stage II 55.7%.
Conclusion: The epidemiological situation of BC in Kazakhstan showed a tendency for improvement, with a decrease in the mortality rate and a rise in the incidence rate. During the study period, the identification of patients with stage II breast cancer prevailed. Substantial variability of epidemiological data among the regions of Kazakhstan indicates the necessity of a detailed study of risk factors of BC and the effectiveness of mammographic screening in the regions in order to take impactful healthcare measures.
Gauhar A. Dunenova1, Zhanna A. Kalmataeva1, Dilyara R. Kaidarova2,
Oksana V. Shatkovskaya 2, Alma Zh. Zhylkaidarova2, Elena A. Marchenko3,
Azhar A. Dyussupova4, Raida I. Faizova4, Nataliya E. Glushkova1
1 Al-Farabi Kazakh National University, Faculty of Medicine and Healthcare, Almaty, Republic of Kazakhstan;
2 Kazakh Research Institute of Oncology and Radiology, Almaty, Republic of Kazakhstan;
3 Invivo, Medical Laboratory, A Limited Liability Partnership, Almaty, Republic of Kazakhstan;
4 NJSC «Semey Medical University», Department of General Medical Practice, Semey, Republic of Kazakhstan
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Dunenova G.A., Kalmataeva Zh.A., Kaidarova D.R., Shatkovskaya O.V., Zhylkaidarova A.Zh., Marchenko E.A., Dyussupova A.A., Faizova R.I., Glushkova N.E. Breast cancer epidemiology in Kazakhstan for the period 2012-2021 // Nauka i Zdravookhranenie [Science & Healthcare]. 2023, (Vol.25) 2, pp. 128-137. doi 10.34689/SH.2023.25.2.018Related publications:
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