KIDNEY CANCER IN EAST KAZAKHSTAN REGION: COMPONENT ANALYSIS OF INCIDENCE (2010-2019)
Introduction. In the world, about 430 thousand new cases of kidney cancer (KC) are diagnosed every year. KC is one of the most important types of cancer, partly because it continues to impose a significant economic burden on the health care system. The study of the incidence of KC has great scientific and practical significance in terms of identifying risk factors, monitoring and evaluating preventive measures and developing new methods of diagnosis and treatment.
The aim of the study is to evaluate the incidence of KC in East Kazakhstan region using component analysis.
Material and research methods. In a retrospective study of the data of the Ministry of Health of the Republic of Kazakhstan on new cases of KC in the East Kazakhstan region, obtained from Form No.7, descriptive and analytical methods of epidemiology were used. To analyze the dynamics of incidence based on the number of cases from 2010 to 2019, a component analysis was used.
Results. During the study period (2010-2019), 1,279 new cases of KC were registered in the East Kazakhstan region. The average annual incidence of KC in East Kazakhstan region was 9.2±0.4 (95%CI=8.4-10.1) per 100,000 population. The overall increase in incidence in the male population was +5.740/0000, and in the female population +3.210/0000. The incidence of KC in both sexes is increasing. The overall increase was +4.420/0000 and depended on changes in the age structure of the population (∑ΔA=+1.110/0000), the risk of getting sick (∑ΔR=+3.130/0000) and the cumulative effect of the age structure and the risk of getting sick (∑ΔAR=+0.180/0000). According to the calculations of the component analysis, 118 patients were expected in 2019. Instead, the number of patients increased to 163. Thus, KC is characterized by an increase in cases, mainly due to a change in the risk of getting sick (+42.0% of the total increase by +56.7%).
Conclusions. Our study shows that the increase in the number of patients is associated with risk factors, with changes in the age structure of the population of the region, which are associated with a change in the age type of the population towards regressive. Improved health policy and awareness of disease prevention can play an important role in reducing the burden of cancer.
Nurbek S. Igissin1,2,3, https://orcid.org/0000-0002-2517-6315
Sergey S. Dyakov4,2,5, https://orcid.org/0000-0001-7566-7094
Zhansaya B. Telmanova2, https://orcid.org/0000-0002-2364-6520
Indira O. Kudaibergenova5,3, https://orcid.org/0000-0003-3007-8127
Zaituna G. Khamidullina6, https://orcid.org/0000-0002-5324-8486
Akzhunis M. Jexenova6, https://orcid.org/0000-0001-9771-0882
Zhanerke R. Azhetova6,2, https://orcid.org/0000-0002-8266-1720
Serikbay T. Orozbaev6,2, https://orcid.org/0000-0003-3895-0426
Gulnur S. Igissinova7,2, https://orcid.org/0000-0001-6881-2257
Zarina A. Bilyalova2,3, https://orcid.org/0000-0002-0066-235X
Saken K. Kozhakhmetov6, https://orcid.org/0000-0002-0075-0376
1 Research Institute of Life and Health Sciences, Higher School of Medicine, Kokshetau University named after Sh. Ualikhanov, Kokshetau, Kazakhstan;
2 Central Asian Institute for Medical Research, Astana, the Republic of Kazakhstan;
3 Asian Pacific Organization for Cancer Prevention, Bishkek, the Kyrgyz Republic;
4 National Scientific Center of Traumatology and Orthopedics named after Academician Batpenov N.D. of the Ministry of Health of the Republic of Kazakhstan, Astana, the Republic of Kazakhstan;
5 Akhunbaev Kyrgyz State Medical Academy, Bishkek, the Kyrgyz Republic;
6 NCJSC «Astana Medical University», Astana, the Republic of Kazakhstan;
7 NCJSC «Asfendiyarov Kazakh National Medical University», Almaty, the Republic of Kazakhstan.
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Igissin N.S., Dyakov S.S., Telmanova Zh.B., Kudaibergenova I.O., Khamidullina Z.G., Jexenova A.M., Azhetova Zh.R., Orozbaev S.T., Igissinova G.S., Bilyalova Z.A., Kozhakhmetov S.K. Kidney cancer in East Kazakhstan region: component analysis of incidence (2010-2019) // Nauka i Zdravookhranenie [Science & Healthcare]. 2023, (Vol.25) 6, pp. 22-29. doi 10.34689/SH.2023.25.6.003Related publications:
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