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THE INFLUENCE OF PREGNANCY-ASSOCIATED PLASMA PROTEIN А (РАРР-А) ON INTRAUTERINE GROWTH RESTRICTION
Introduction: the search of methods enabling to predict fetal growth impairment is an important issue for modern obstetrics. Pregnancy-associated plasma protein А (РАРР-А) is considered to be one of the predictors of fetal chromosomal mutations. The associations between reduced РАРР-А levels in first pregnancy trimester and the development of intrauterine growth restriction (IUGR) is being extensively studied over the last years. The current normal range of РАРР-А in Kazakhstan is considered to be 0,5-2,05.
Aim: to study the associations between РАРР-А levels in first pre... More
Aim: to study the associations between РАРР-А levels in first pre... More
2017 year | Issue: 5 | Pages: 55-66
FACTORS INFLUENCING ON ADHERENCE TO ANTIHYPERTENSIVE THERAPY AT PATIENTS WITH ARTERIAL HYPERTENSION IN EAST KAZAKHSTAN
Aim of research – to analyse influence of social-economical, clinical and pharmaco-epidemiological factors to patients’s compliance on the treatment in population of East Kazakhstan.
Materials and methods: Study design – cross-sectional study. The study included 2346 patients with arterial hypertension aged 25 to 80 years, including 1281 men (54,6%) and 1065 women (45,4%). The average age is 55,2 ± 1,1 years.
Carried out estimation of compliance to medical therapy at patients with arterial hypertension. Depending on the degree of compliance, estimated patien... More
Materials and methods: Study design – cross-sectional study. The study included 2346 patients with arterial hypertension aged 25 to 80 years, including 1281 men (54,6%) and 1065 women (45,4%). The average age is 55,2 ± 1,1 years.
Carried out estimation of compliance to medical therapy at patients with arterial hypertension. Depending on the degree of compliance, estimated patien... More
2017 year | Issue: 5 | Pages: 42-54
A REVIEW OF METHODS FOR CREATING PERCENTILE GROWTH RATE CHARTS OF FUNDAL HEIGHT DURING PREGNANCY. REVIEW
Introduction: Pregnancy management using centile growth charts of the standing height of the uterus during pregnancy (gravidogram), reveals a group of women with potential fetal growth disorders. The sensitivity and diagnostic value of the method depends on the methods by which the graph was created. In methods, it is important to consider variables that affect the graph, statistical methods of processing.
The purpose of the study: the study of methods for developingchartsoffundalheight (FH).
Methods: a review of the publications in the Google Scolar, ... More
The purpose of the study: the study of methods for developingchartsoffundalheight (FH).
Methods: a review of the publications in the Google Scolar, ... More
2017 year | Issue: 4 | Pages: 81-93
COMPARATIVE ASSESSMENT OF QUALITY OF LIFE of PATIENTS IN TRADITIONAL AND HYPOFRACTIONATED REGIMENS OF RADIOTHERAPY OF BREAST CANCER
Background: At present, more and more researchers are paying attention to the fact that during the treatment of cancer patients it is necessary to assess the quality of their life. There are many new data on the evaluation of the quality of life in cancer multicenter studies, in which the quality of life is the main criterion for assessing the effectiveness of treatment. The study of the quality of life allows you to obtain additional information about many aspects of the patient's condition, both before and during the treatment.
The goal is to make a comparative assessment of... More
The goal is to make a comparative assessment of... More
2017 year | Issue: 4 | Pages: 71-80
SKIN TOXICITY AFTER HYPOFRACTIONATED RADIOTHERAPY IN THE COMPLEX TREATMENT PROGRAM OF BREAST CANCER
Background: Radiation therapy is a necessary component of breast cancer complex treatment program, that reducing the frequency of relapses and increasing the life expectancy of patients. Daily fractions use of 2 Gy to a total focal dose of 50 Gy is the traditional standard scheme for radiotherapy treatment. However, like any other treatment method, radiation therapy provides a variety of adverse effects on normal tissues in the irradiated field. Acute radiation reactions of the skin are one of the most frequent side effects of this type of treatment. A practical solution to the problem is deve...
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2017 year | Issue: 4 | Pages: 63-70