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                            DOING AN INFORMATION STUDY IN MEDICINE: TIPS ABOUT STRATEGIES AND RECOURSES FOR LITERATURE REVIEW
                        
            
                
                
                    
            
            
        
                    
                
                The current paper presents a short review of the legislative frames of information study in medicine, also it was done review of essential resources as bibliographic databases as others. It is described different strategies of information search that depend on the goal of the review (the plan of information study and inclusion criteria). This paper is devoted to essentials while review process in the frame of medical scientific research and health technology assessment.                
                                    
                                
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                                                    2019 year                                                                            | Issue: 3                                                                            | Pages: 68-76                                            
                
                            DIAGNOSTIC SIGNIFICANCE OF THE HE-4 TUMOR MARKER IN THE STAGING OF OVARIAN CANCER
                        
            
                
                
            
                
                
                    
            
            
        
                    Ovarian cancer is not a rare pathology and accounts for 4–6 % of all malignant neoplasms in the female population. Diagnostics of ovarian cancer at an early stage is a key approach to improving the effectiveness of treatment for this pathology. The use of sensitive serological tumor-associated markers is considered an adequate approach for diagnosis, monitoring of treatment efficacy and preclinical detection of recurrence for tumors of a number of localizations, in particular ovarian cancer.
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                                                    2017 year                                                                            | Issue: 6                                                                            | Pages: 28-42                                            
                
                            COX REGRESSION IN HEALTH SCIENCES  USING SPSS SOFTWARE
                        
            
                
                
                    
            
            
        
                    
                
                In this paper presents theoretical bases of the Cox regression as one of the most popular multidimensional methods of survival analysis. This method of analysis in most cases is used to determine the independent influence of potential risk factors on the rate of occurrence of the event under study during the time period studied. The practical example describes the principles of Cox proportional hazard analysis and the basic principles of interpreting the information received with the SPSS application statistical software package.                
                                    
                                
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                                                    2017 year                                                                            | Issue: 6                                                                            | Pages: 5-27                                            
                
                            METHODOLOGICAL BASIS OF THE ORGANIZATION OF MEDICAL AND ENVIRONMENTAL RESEARCH TO ASSESS THE HEALTH STATUS OF  THE POPULATION LIVING IN ECOLOGICALLY UNFAVORABLE TERRITORIES OF KAZAKHSTAN
                        
            
                
                
                    
            
            
        
                    
                
                Background. Problem of population health status and life span is the strategic task in Kazakhstan. The present time in the most industrial territories of Kazakhstan there is situation related with increasing of technogenic and anthropogenic risk factors influence to environment and rising of ecological load for the population. East-Kazakhstan, Pavlodar, Karaganda and Aktobe regions are such ecologically unfavorable areas. 
Aim: description of the methodological and procedural framework for the implementation of the scientific program “Development of scientific and methodological bases fo... More
            Aim: description of the methodological and procedural framework for the implementation of the scientific program “Development of scientific and methodological bases fo... More
                                                    2017 year                                                                            | Issue: 5                                                                            | Pages: 29-41                                            
                
                            SURVIVAL ANALYSIS IN HEALTH SCIENCES USING SPSS SOFTWARE
                        
            
                
                
                    
            
            
        
    
            
    
                
                In this paper we present theoretical basis of the two methods of survival analysis for the prognosis of survival dependent on one or two independent variables during the time period with the use of SPSS software. We describe the main principles of Kaplan-Meier analysis and survival tables for one or several groups. Special emphasis is given to interpretation of the results and practical examples                
                                    
                                
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                                                    2017 year                                                                            | Issue: 5                                                                            | Pages: 5-28                                            
                