COMORBIDITY IN OSTEOARTHRITIS
Introduction. Comorbid pathology, which accompanies most chronic non-communicable diseases, not only negatively affects the treatment of patients, but also significantly worsens their quality of life. Osteoarthritis (OA) is an age-related disease characterized by high comorbidity.
Aim: to identify the most common comorbid conditions in patients with OA.
Materials and methods: Study Design: The study is prospective, controlled. The study period is from September 01 to December 01, 2022. in the KGP on the REM "City Polyclinic" No. 5. 60 patients with a reliable diagnosis of OA were examined, including 12 men (20%), 48 women (80%), mean age (63.37±10.1 years), mean duration of illness (6.89±7.45). All patients signed an informed consent prior to the start of the study. Statistical processing of the obtained data was carried out using the Statistica-6 program, where p<0.05 was considered significant.
Results. Mostly dominated by women 86.7%, over 50 years old. Out of 60 patients with OA, gonarthrosis was detected in 44 (73.3%), coxarthrosis in 4 (6.7%), generalized form - in 12 (20%), with the prevalence of patients with X-ray stage II. All 60 patients with OA had concomitant diseases, of which 92.2% had two or more comorbid pathologies. The leading place in the structure of comorbidity was occupied by pathology of the cardiovascular system in 31 (51.7%) patients, including arterial hypertension (AH) in 18 (58%) patients, coronary heart disease (CHD) in 13 (42%) patients, with this was dominated by angina pectoris II functional class. The mean systolic pressure at baseline and over time was 123.39±17.02 mm Hg. Art., indicators of diastolic pressure initially and in dynamics were within 82.62±5.05. In second place is endocrine pathology in 16 (26.7%) patients. Six (10%) patients had osteoporosis (OP) and received bisphosphonates.
Conclusions. Almost all OA patients have a comorbid pathology, while in 92.2% of cases patients have two or more concomitant diseases. The most common comorbidities are diseases of the cardiovascular system (51.7%, including hypertension in 58% of patients), diseases of the endocrine system in 16 patients (26.7%), of which obesity in 8 (50%), Type 2 diabetes in 5 (31.3%), hypothyroidism in 3 (18.7%), respectively, and OP in 10% of patients.
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Nogaeva M.G., Khabizhanova V.B., Tazhiyeva A.Е., Goremykina M.V., Issayeva S.M., Dilmanova D.S. Comorbidity in osteoarthritis // Nauka i Zdravookhranenie [Science & Healthcare]. 2024. Vol.26 (6), pp. 106-115. doi 10.34689/SH.2024.26.6.013Related publications:
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COMORBIDITY IN OSTEOARTHRITIS