Clinical and epidemiological characteristics of metastatic breast cancer in the north-eastern region of Kazakhstan
Actuality: Breast cancer (BC) is one of the most common diseases in the world among women. BC and its metastasis is a heterogeneous group of tumors that differ in morphology, clinical course, and sensitivity to the treatment, which is a serious clinical problem in oncology, thereby causing interest in this problem.
The aim of the study is to investigate the prevalence and clinical and morphological features of metastatic BC.
Materials and Methods: Design is retrospective study including 570 case histories. A retrospective analysis of data metastatic BC for the 2004-2013 years according to the Regional Oncology Center of Semey and the Regional Oncology Center in Pavlodar .Statistical analysis was carried out in the SPSS20.0 program.
Results: Mean age was 55.1 years. Ethnicity: Russians = 319 (56.0%), Kazakhs = 71 (30.0%), others = 80 (14.0%). Side of lesions: right -300 (52.6%), left- 264 (46.3%), both-6 (1.1%). Localization: upper outer quadrant (n = 289; 50.7%), upper inner quadrant (n = 86; 15.1%), center (n = 62; 10.9%), remaining 7%. Molecular type: lum A - 76 (30%), TN - 79 (31.2%), lum B negative 42 (16.6%), lum B positive - 20 (7.9%) and HER2 + - 36 (14.2%). Histological form: invasive ductal, (57.7%), invasive lobular (n = 58; 10.2%) type, the "other" type (n = 161; 28.2%) and the other less than 2%. Stage III - 43,2%, II stage - 40,8%, IV stage - 14.2% and I - 1,8%.
Conclusions: Conclusions: The clinical and epidemiological characteristics of metastatic breast cancer in the North-East region of Kazakhstan has no geographical features, it is inherent in a global trend of breast cancer traits. However, the fact that among patients with metastatic breast cancer Kazakhs younger than the patient's Russian nationality requires further in-depth study.
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Абильтаева А.А., Адылханов Т.А., Мысаев А.О. Клинико-эпидемиологическая характеристика метастатического рака молочной железы в Северо-Восточном регионе Казахстана / / Наука и Здравоохранение. 2016. №4. С. 74-83. Abiltaeva A.A., Adylhanov T.A., Myssayev A.O. Clinical and epidemiological characteristics of metastatic breast cancer in the North-Eastern region of Kazakhstan. Nauka i Zdravookhranenie [Science & Healthcare]. 2016, 4, pp. 74-83. Абильтаева А.А., Адылханов Т.А., Мысаев А.О. Солтүстік- Шығыс Қазақстан өңірі бойынша сүт безінің метастатикалық обырының клиникалық және эпидемиологиялық сипаттамасы / / Ғылым және Денсаулық сақтау. 2016. №4. Б. 74-83.Related publications:
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