HORMONALLY ACTIVE FAT TISSUE IN PATIENTS WITH OSTHEOARTHRITIS AND OBESITY
Studed the content and role of adipose tissue adypokin`s – apelin in patients with osteoarthritis (OA) and when it is combined with obesity (32 out of all surveyed). Determined a significant increase in this indicator in patients with obesity and OA. A direct correlation between the level of apelin and body mass index (r=0,43), apelin and insulin resistance (r=0,46) and reverse – with long history on DOA (r=-0,61). Patients with OA and normal weight level was increased insignificantly apelin compared with the control. Defining the role of apelin in the body – carries the catabolism of cartilage – this indicator can be used for diagnostic purposes.
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Pasiyeshvili L. M., Tereshkin K. I. Hormonally active fat tissue in patients with ostheoarthritis and obesity. Nauka i Zdravoohranenie [Science & Healthcare]. 2015, 3, pp. 64-69.