Science & Healthcare

In this paper we present basic principles of planning and carrying out case-control studies in health sciences as well as analyzing the data collected in these studies. We present practical examples of sample size and effect measures calculation for matched and unmatched case-control studies using online calculators and Epi Info software. Examples of studies using case-control design from international peer-reviewed literature are also presented. This article provides general introduction to case-control studies and does not substitute specialized literature in clinical epidemiology.