Online ISSN: 3007-0244,
Print ISSN:  2410-4280
PROGNOSTIC VALUE OF RENAL DYSFUNCTION IN PATIENTS WITH ISCHEMIC HEART DISEASE AFTER MYOCARDIAL REVASCULARIZATION
The Aim. Study about disturbance of renal dysfunction (RD) and its prognostic significance in patients with ischemic heart disease (IHD) who have undergone myocardial revascularization. Materials and methods. 675 patients from cardiology department were analyzed by retrospective analysis of history of the disease, in which there was a transfer of percutaneous coronary intervention (PCI) and / or coronary artery bypass surgery. The prevalence of risk factors, features of coronary blood flow, structural and functional changes of the heart were studied. Statistical processing was performed by SPSS 20.0: descriptive statistics, Mann-Whitney U-test for independent samples, Chi-square, single-factor and multifactorial logistic regression. Differences between the compared variables were considered significant at p<0.05. Results. PD was detectedin 163 (24,1%) patients, their age was significantly older (p<0,001). The main factors of cardiovascular risk were: arterial hypertension (AH), diabetes mellitus (DM), myocardial infarction (MI) and acute violation of cerebral circulation (AVCC). In 14,2% of cases death was detected from all causes, in the group with PD, significantly more than without (21,5% vs. 11,9%, p=0,002). As a result of a multifactor regression analysis, factors affecting the adverse course of the disease were established: age (p<0,001), creatinine level (p=0,026), EF LV (p<0,001). Conclusion. Renal dysfunction is one of the main independent predictors of adverse outcome in ischemic heart diseasein patients after myocardial revascularization.
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